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total thyroidectomy and radioactive iodine ablation at the Thyroid Cancer Clinic of our Institute and to assess which of these most accurately predicted outcomes using clinical end points. The secondary objective was to compare the performance of the
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Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
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individuals with and without MetS as well as evaluating the incidence of TD and trend of thyroid hormones according to the MetS group, during a 10 year follow-up in an iodine sufficient population. Materials and Methods Study Design TTS is a
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Graves’ hyperthyroidism since 1988, for which he had been treated with methimazole for 8 years, and then with radioactive iodine (in 1996), with consequent hypothyroidism, for which he was on L-thyroxine 150 µg/day. He reported the appearance of bilateral
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with 30 mCi of iodine 131 and oral LT4. During the following 3 years he had an excellent response receiving oral LT4 150 μg/day (2.14 μg/kg/day). In November 2017, he was hospitalized for intestinal subocclusion and secondary malabsorptive syndrome
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hyperthyroidism is 1.2–1.6, 0.5–0.6 overt and 0.7–1.0% subclinical [ 1 , 5 ]. The most frequent causes are Graves’ disease (GD) and toxic nodular goiter. GD is the most prevalent cause of hyperthyroidism in iodine-replete geographical areas, with 20–30 annual
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radioactive iodine (RAI), US should be obtained a few months later in all patients as part of the investigation that defines the response to therapy [ 1 - 3 ]. After this first assessment, the American Thyroid Association (ATA) [ 2 ] and the European Thyroid
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Introduction Treatment with lenvatinib (LEN), a multitarget tyrosine kinase inhibitor (TKI), has shown great efficacy in patients with advanced radioactive iodine-refractory (RAI-R) thyroid cancer (TC), both in clinical trials and in a real
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vast majority of the thyroid nodule population but are not intended for pediatric cases. While TA is covered, in extenso, EA and radioactive iodine ablation procedures for thyroid nodules are only mentioned in passing. How the diagnosis of a benign
Institute of Pathology, University Hospital Halle (Saale), Halle (Saale), Germany
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were found in 12.6% of patients and RET gene fusions in 14.3% ( 13 ). The prevalence of fusions increases for metastatic/advanced patients’ WT of other aberrations. In radioactive iodine (RAI)-resistant metastatic thyroid cancers without BRAF
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Introduction Differentiated thyroid cancer (DTC) accounts for nearly 90% of all thyroid cancer cases ( 1 ). The standard initial treatment is surgery followed by radioactive iodine (RAI) or observation; however, approximately 5–15% of patients