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Sylvie Hiéronimus Department of Endocrinology, Diabetology and Reproductive Medicine, University Hospital of Nice

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Françoise Brucker-Davis Department of Endocrinology, Diabetology and Reproductive Medicine, University Hospital of Nice
Institut National de la Recherche Médicale, UMR U895, University Nice-Sophia-Antipolis, Nice, France

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showed that iodine deficiency was usually mild at the beginning; in the supplemented group in the third trimester, the median UIE reached 160 μg/l, suggesting iodine sufficiency. As in all studies, there is a wide range of values showing that some women

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Earn H. Gan Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom

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Anna L. Mitchell Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom

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Ruth Plummer Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom

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Simon Pearce Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom

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Petros Perros Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom

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clinical evidence of Graves orbitopathy. Biochemical tests showed a serum thyroid-stimulating hormone (TSH) which was fully suppressed with a raised free T3 of 13.0 pmol/L (reference range 3.5–6.5) and free T4 of 27.6 pmol/L (reference range 9

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Luca Persani Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Georg Brabant Experimental and Clinical Endocrinology Medical Clinic I – University of Lübeck, Lübeck, Germany

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Mehul Dattani Genetics and Genomic Medicine Programme, UCL GOS Institute of Child Health, London, United Kingdom

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Marco Bonomi Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Ulla Feldt-Rasmussen Department of Medical Endocrinology and Metabolism, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

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Eric Fliers Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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Annette Gruters Department for Pediatric Endocrinology and Diabetes, Charité University Medicine, Berlin, Germany
University Hospital Heidelberg, Heidelberg, Germany

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Dominique Maiter Department of Endocrinology and Nutrition, UCL Cliniques Saint-Luc, Brussels, Belgium

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Nadia Schoenmakers University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke’s Hospital and National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, United Kingdom

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A.S. Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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replacement is achieved, pediatric patients with CeH should undergo monitoring of FT4 according to the age-related reference ranges and should be monitored like patients with primary hypothyroidism. An annual monitoring of FT4 should be sufficient in adult CeH

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Ying Sun Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Di Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Lei Zhao Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China

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Xiaoguang Shi Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Yongze Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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reference limit (0.27–4.20 mIU/L). The normal reference ranges for thyroid function were, TSH, 0.27–4.2 mIU/L; fT4, 12.0–22.0 pmol/L; fT3, 3.1–6.8 pmol/L; TPOAb, <34.0 IU/mL; and TgAb, <115.0 IU/mL, as reported by the test kit manufacturers. The UIC was

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Catarina Silvestre Department of Endocrinology, Diabetes and Metabolism, Santa Maria Hospital, Lisbon, Portugal

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Joaquim Sampaio Matias Department of Laboratorial Medicine, Santa Maria Hospital, Lisbon, Portugal

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Helena Proença Department of Laboratorial Medicine, Santa Maria Hospital, Lisbon, Portugal

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Maria João Bugalho Department of Endocrinology, Diabetes and Metabolism, Santa Maria Hospital, Lisbon, Portugal

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(NTD) has been reported to range from 0.3 to 1.4% [ 2 , 4 , 5 ]. There is evidence that serum Ctn measurement in patients with thyroid nodules can result in earlier detection of MTC and/or “C” cell hyperplasia, prior to malignant transformation, in

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Axel Sahovaler Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada
Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada

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Marco Ferrari Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada
Unit of Otorhinolaryngology – Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy
Section of Otorhinolaryngology – Head and Neck Surgery, Department of Neurosciences, University of Padua, Padua, Italy

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Jonathan Athayde Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Adrian Mendez Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Kevin Fung Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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John Yoo Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Anthony C. Nichols Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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S. Danielle MacNeil Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Materials) organizing studies based on the tumor sizes. We proceeded to strictly extract from this table articles with 1–4 cm tumors, as it represents the size range where less clear recommendations exist to date, obtaining 4 studies [ 6 - 9 ]. The forest

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Dominik Spira Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Nikolaus Buchmann Department of Cardiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Marcus Dörr Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Marcello R P Markus Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Matthias Nauck German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany

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Sabine Schipf Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Joachim Spranger Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Ilja Demuth Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Charité – Universitätsmedizin Berlin, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany

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Elisabeth Steinhagen-Thiessen Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Henry Völzke German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Till Ittermann Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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with low thyroid function and prediabetes seem to be more likely to progress to type 2 diabetes compared to those with prediabetes and thyroid hormone levels in the reference range ( 6 ). The effects of subclinical hypo- or hyperthyroidism on glucose

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Patrick Aidan ENT Unit, American Hospital of Paris, Neuilly sur Seine, France

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Helen Pickburn ENT Unit, American Hospital of Paris, Neuilly sur Seine, France

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Hervé Monpeyssen Endocrinology Unit, American Hospital of Paris, Neuilly sur Seine, France

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Gilles Boccara Department of Anaesthesia and Intensive Care, American Hospital of Paris, Neuilly sur Seine, France

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range of motion via multiarticulated instruments [ 8 , 9 ]. The use of the da Vinci System in the gasless transaxillary approach to thyroid surgery has been proven to be effective in the management of thyroid cancer [ 10 , 11 , 12 , 13 , 14 , 15 ]. It

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Rui Guo Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Bowen Zheng Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Tao Wu Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Yufan Lian Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Tinghui Yin Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Yuting He Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Jingya Qin Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Zhicheng Yao Department of General Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Wen Xu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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Jie Ren Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China

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that the symptom scores ranged from 0 to 5. RFA procedure When we ablated multiple nodules, to avoid causing serious damage to the recurrent laryngeal nerves, all the dominant nodules in the ipsilateral thyroid lobe were ablated first, starting

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Genfeng Yu Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Siyang Liu Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Cheng Song Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Qintao Ma Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Xingying Chen Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Yuqi Jiang Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Hualin Duan Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Yajun He Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Dongmei Wang Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Heng Wan Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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Jie Shen Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China

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syndrome is defined as T3 levels below the lower limit of normal. However, we included in this study a population with FT3, FT4, and TSH, all within the reference range. Therefore, FT3/FT4 is superior to FT3 in a population with normal thyroid function

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