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Dong Gyu Na Department of Radiology, Human Medical Imaging and Intervention Center, Seoul, South Korea

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Hye Sook Min Departments of Pathology, Seoul, South Korea

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Hunkyung Lee Department of Pathology, Ewha Clinical Laboratory, Seoul, South Korea

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Jae-Kyung Won Departments of Pathology, Seoul, South Korea

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Hyo Bin Seo Department of Radiology, Seoul National University Hospital Kangnam Center, Seoul, South Korea

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Ji-Hoon Kim Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea

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pathology of a papillary thyroid carcinoma. a This CNB histology specimen shows tumor cells with an atypical papillary growth pattern (lower thick arrow), diagnosed as papillary thyroid carcinoma. The specimen also shows a normal gland (upper thick arrow

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Yuwei Liu Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Shengcai Wang Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Yanzhen Li Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Xuexi Zhang Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Zhiyong Liu Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Qiaoyin Liu Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Nian Sun Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Jie Zhang Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Wentong Ge Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Yongli Guo Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Yuanhu Liu Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Xiaolian Fang Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Tingting Ji Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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Jun Tai Children’s Hospital Capital Institute of Pediatrics, Department of Otolaryngology, Head and Neck Surgery, Beijing, China

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Xin Ni Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China

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, Iliadou PK , Mandanas S , Vasileiadis T , Mitsakis P , Tziomalos K , . Papillary thyroid carcinomas in patients under 21 years of age: clinical and histologic characteristics of tumors ≤10 mm . J Pediatr . 2015 ; 166 ( 2 ): 451 – 6 . 14

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Nicholas S. Andresen Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Buatti Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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Hamed H. Tewfik Iowa City Cancer Treatment Center, Iowa City, Iowa, USA

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Nitin A. Pagedar Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, USA

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Carryn M. Anderson Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Watkins Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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, Gorman CA, Maurer MS, McIver B, Mullan BP, Oberg AL, Powell CC, van Heerden JA, Goellner JR: Papillary thyroid carcinoma managed at the Mayo Clinic during six decades (1940–1999): temporal trends in initial therapy and long-term outcome in 2

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L. Leenhardt Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France

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M.F. Erdogan Department of Endocrinology and Metabolism, University of Ankara School of Medicine, İbni Sina Hastanesi, Ankara, Turkey

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L. Hegedus Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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S.J. Mandel Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., USA

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R. Paschke Department of Endocrinology, University of Leipzig, Leipzig, Germany

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T. Rago Endocrine Unit 1, Department of Internal Medicine, Ospedale Cisanello, University of Pisa, Pisa, Italy

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G. Russ Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France

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: Papillary and follicular thyroid carcinoma. N Engl J Med 1998;338:297-306. 10.1056/NEJM199801293380506 9445411 6 Frasoldati A, Pesenti M, Gallo M, Caroggio A, Salvo D, Valcavi R: Diagnosis of neck recurrences in patients with differentiated thyroid

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Maria Rossing Department of Endocrinology, Herlev University Hospital, Herlev
Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Birte Nygaard Department of Endocrinology, Herlev University Hospital, Herlev

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Finn Cilius Nielsen Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Finn Noe Bennedbæk Department of Endocrinology, Herlev University Hospital, Herlev

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Frates et al. [ 7 ] the accumulated predicted value of US characteristics and basic clinical features ranged between 3 and 48%. The papillary thyroid microcarcinoma (PTMC) is a papillary thyroid carcinoma with a size of ≤1 cm. The overall incidence of

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Henning Dralle Department of General, Visceral and Vascular Surgery, University Hospital, Medical Faculty, University of Halle-Wittenberg, Halle/Saale, Germany

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.1082 22351858 11 Kang SW, Lee SH, Park JH, Jeong JS, Park S, Lee CR, Jeong JJ, Nam KH, Chung WY, Park CS: A comparative study of the surgical outcome of robotic and conventional open modified radical neck dissection for papillary thyroid carcinoma with

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Luca Damiani Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy

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Sabrina Lupo Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Roberta Rossi Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Stefania Bruni Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Mirco Bartolomei Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy

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Stefano Panareo Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy

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Paola Franceschetti Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Paolo Carcoforo Department of Morphology, Section of Surgery, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy

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Giovanni Lanza Department of Medical Sciences, Pathology Unit, University of Ferrara, Ferrara, Italy

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Stefano Pelucchi Department of Biomedical and Surgical Specialization Sciences, University of Ferrara, Ferrara, Italy

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Ettore Degli Uberti Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Maria Chiara Zatelli Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Papillary Thyroid Carcinoma (PTC) incidence is ­increasing worldwide; despite excellent prognosis, 30% of patients may present persistent disease (PoD) or relapse [ 1 - 4 ]. The identification of novel prognostic markers is a matter of great

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Kaoru Kobayashi Kuma Hospital, Kobe, Japan

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Hisashi Ota Kuma Hospital, Kobe, Japan

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Mitsuyoshi Hirokawa Kuma Hospital, Kobe, Japan

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Tomonori Yabuta Kuma Hospital, Kobe, Japan

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Mitsuhiro Fukushima Kuma Hospital, Kobe, Japan

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Hiroo Masuoka Kuma Hospital, Kobe, Japan

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Takuya Higashiyama Kuma Hospital, Kobe, Japan

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Minoru Kihara Kuma Hospital, Kobe, Japan

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Yasuhiro Ito Kuma Hospital, Kobe, Japan

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Akihiro Miya Kuma Hospital, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Kobe, Japan

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Press, 2004, pp 67-72. 14 Quiros RM, Ding HG, Gattuso P, Prinz RA, Xu X: Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations. Cancer 2005;103:2261-2268. 15 Wiseman

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Luigino Dal Maso Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Daniela Pierannunzio National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy

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Silvia Francisci National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy

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Angela De Paoli Epidemiological Department, Azienda Zero, Padova, Italy

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Federica Toffolutti Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Salvatore Vaccarella Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France

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Silvia Franceschi Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Ugo Fedeli Epidemiological Department, Azienda Zero, Padova, Italy

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of the DEPTH Working Group
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tertiary centers, and subsequently at the population level from the California Cancer Registry ( 16 ). In updated analyses of the NCD, among patients with papillary thyroid carcinoma (PTC) submitted to TT, adoption of RAI decreased from 61% in 2004 to 44

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Antonis Polymeris Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Christina Kogia Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Dimitrios Ioannidis Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Dimitrios Lilis Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Maria Drakou Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Nicoletta Maounis Department of Cytology/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Loukas Kaklamanis Department of Pathology/Mediterraneo Hospital, Glyfada, Greece

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Sofia Tseleni-Balafouta First Department of Pathology/University of Athens, Medical School, Athens, Greece

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a CSF producing papillary thyroid carcinoma associated with neutrophilia also from our department [ 30 ]. Table 1. Review of the literature In conclusion, this is the first case of aggressive ATC in Greece associated with initially

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