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L.A. Jonker Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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C.A. Lebbink Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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M.C.J. Jongmans Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

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R.A.J. Nievelstein Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Pediatric Radiology and Nuclear Medicine, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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J.H.M. Merks Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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E.J.M. Nieveen van Dijkum Department of Surgery, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands

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T.P. Links Department of Endocrinology, University Medical Center Groningen, Groningen, The Netherlands

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N. Hoogerbrugge Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands

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A.S.P. van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands

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H.M. van Santen Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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weeks, one node was removed (surgical approach chosen over fine-needle aspiration cytology on surgeon’s preference) for pathological examination, which demonstrated a reactive lymph node without signs of malignancy. Despite this reassuring result, later

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000508872
Volume/Issue:
Volume 9: Issue 5
Open access
Mohamed Abdouh Cancer Research Program, McGill University Health Centre-Research Institute, Montreal, Québec, Canada

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Roger Tabah Department of Surgery and Department of Oncology, McGill University Health Centre, Montreal, Québec, Canada

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Vincenzo Arena Department of Obstetrics and Gynecology, Santo Bambino Hospital, Catania, Italy

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Manuel Arena Fondazione Istituto G. Giglio Cefalù, Pisciotto, Italy

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Zu-hua Gao Department of Pathology, McGill University Health Centre-Research Institute, Montreal, Québec, Canada

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Aurelio Lorico College of Medicine, Touro University Nevada, Henderson, Nevada, USA
Istituto Oncologico del Mediterraneo, Viagrande, Italy

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Goffredo Orazio Arena Fondazione Istituto G. Giglio Cefalù, Pisciotto, Italy
Istituto Oncologico del Mediterraneo, Viagrande, Italy
Department of Surgery, McGill University, St. Mary Hospital, Montreal, Québec, Canada

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difficulty in distinguishing benign from malignant tumors. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a means of coming to a definitive diagnosis

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000516421
Volume/Issue:
Volume 10: Issue 4
Free access
Emilio Fiore Department of Experimental and Clinical Medicine, Endocrinology Unit 1, University Hospital of Pisa, Pisa, Italy

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Francesco Latrofa Department of Experimental and Clinical Medicine, Endocrinology Unit 1, University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Experimental and Clinical Medicine, Endocrinology Unit 1, University Hospital of Pisa, Pisa, Italy

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submitted to fine-needle aspiration of thyroid nodules and to thyroid surgery [ 51 ]. We showed that the prevalence of TAb was similar in patients with benign nodules as compared to patients with malignant nodules at cytology (38.7 vs. 35.6%, respectively

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000371741
Volume/Issue:
Volume 4: Issue 1
Free access
Tommaso Piticchio Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi Nesima Hospital, University of Catania, Catania, Italy
Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland

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Gilles Russ Department of Thyroid and Endocrine Tumor Diseases, La Pitie-Salpetriere Hospital, 83 Bd de l’Hopital, Paris, France

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Maija Radzina Riga Stradins University, Radiology Research Laboratory, Riga, Latvia
University of Latvia, Faculty of Medicine, Riga, Latvia

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Francesco Frasca Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi Nesima Hospital, University of Catania, Catania, Italy

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Cosimo Durante Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

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Pierpaolo Trimboli Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland
Facoltà di Scienze Biomediche, Università della Svizzera Italiana (USI), Lugano, Switzerland

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risks; (3) assess TNs according to risk classes; and (4) select TNs for fine needle aspiration cytology (FNAC) ( 7 ). The advent of TIRADSs has resulted in a substantial increase in published papers, thereby strengthening the evidence in the field. In

Article Type:
Review Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0242
Volume/Issue:
Volume 13: Issue 2
Open access
Mohamed E. Ahmed Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Mohamed A. Mahgoub Khartoum Teaching Hospital, Khartoum, Sudan

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Mohamed G. Alnedar Khartoum Teaching Hospital, Khartoum, Sudan

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Seif I. Mahadi Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Maha Alzubeir Surgery, Faculty of Medicine, Khartoum, Sudan

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Lamyaa A.M. El Hassan University of Ahfad, Khartoum, Sudan

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ElWaleed M. Elamin Alzaeim Alazhari University, Khartoum, Sudan

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Ahmed Mohammed El Hassan University of Khartoum, Khartoum, Sudan

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, teratoma, thyroid disease, and lymphoma [ 8 , 11 ]. Retrosternal goiter with pressure symptoms needs surgical treatment [ 12 , 13 , 14 ]. Assessment of the mediastinal mass will need both CT-guided fine-needle aspiration cytology. However, in our case the

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000364822
Volume/Issue:
Volume 3: Issue 3
Free access
Shigenobu Nagataki Nagasaki University, Ito Hospital, and Radiation Effects Association, Tokyo, Japan

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on March 11, 2011) [ 3 , 4 ]. The participation rate was 81.7% (300,476 of 367,672 children), and 116 patients (39 males and 77 females) were identified as having malignant or suspected malignant thyroid nodules (by ultrasound examination and fine-needle

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000448890
Volume/Issue:
Volume 5: Issue 4
Free access
Andrew J Bauer Division of Endocrinology and Diabetes, The Children’s Hospital of Philadelphia, Department of Pediatrics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Jonathan D Wasserman Division of Endocrinology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada

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Steven G Waguespack Department of Endocrine Neoplasia and Hormonal Disorders and Department of Pediatrics-Patient Care, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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may be monitored versus those that should undergo fine-needle aspiration, (2) refine stratification of thyroid nodules with indeterminate cytology (incorporating the option for oncogene analysis in select cases based on accumulating knowledge of

Article Type:
Article Commentary
Collections:
Pediatric thyroid diseases
DOI:
https://doi.org/10.1530/ETJ-22-0180
Volume/Issue:
Volume 11: Issue 6
Open access
Guo-Qiang Zhang Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Chen-Tian Shen Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Hong-Jun Song Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Zhong-Ling Qiu Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Quan-Yong Luo Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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aspiration biopsy or surgery; and (4) lesions were detected by US and accompanied by elevated serum Tg during follow-up, and were finally confirmed by fine needle aspiration biopsy or surgery. Disease-free survival (DFS) was defined as the time from the date

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000505811
Volume/Issue:
Volume 9: Issue 3
Free access
Roberto Negro Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy

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Matteo Rucco United Technology Research Center, Trento, Italy

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Annalisa Creanza Division of Endocrinology and Metabolism, Mauriziano Hospital Umberto I, Turin, Italy

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Alberto Mormile Division of Endocrinology and Metabolism, Mauriziano Hospital Umberto I, Turin, Italy

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Paolo Piero Limone Division of Endocrinology and Metabolism, Mauriziano Hospital Umberto I, Turin, Italy

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Roberto Garberoglio Division of Endocrinology and Metabolism, Molinette Hospital, Turin, Italy

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Stefano Spiezia Endocrine Surgery, Ospedale del Mare, ASL NA1 Centro, Naples, Italy

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Salvatore Monti Endocrinology Unit, Azienda Ospedaliera Universitaria Sant’Andrea, Rome, Italy

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Christian Cugini Radiology Department, Villa Salus Hospital, Venice, Italy

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Ghassan El Dalati Radiology Department, Policlinico G.B. Rossi, Verona, Italy

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Maurilio Deandrea Division of Endocrinology and Metabolism, Mauriziano Hospital Umberto I, Turin, Italy

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patients with cytologically benign nodules subjected to RF at six Italian Institutions (benignity was confirmed by two repeated fine-needle aspirations, Class II of Bethesda reporting system). Data from 337 patients were obtained from a prospective study

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000504882
Volume/Issue:
Volume 9: Issue 4
Free access
Yanping Ma Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Tao Wu Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Zhicheng Yao General Surgery Department, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Bowen Zheng Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Lei Tan Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Ge Tong Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Yufan Lian Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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Jung Hwan Baek Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Jie Ren Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou City, China

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). Fig. 1. Flowchart of patient enrollment. RFA, radiofrequency ablation. Pretreatment Evaluation Before the procedure, the ultrasonography (US) findings, fine-needle aspiration findings, contrast-enhanced US (CEUS) findings, and

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000519625
Volume/Issue:
Volume 10: Issue 6
Open access