Helmi Khadra
Helmi Khadra
Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana, USA
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Ahmed Deniwar
Ahmed Deniwar
Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana, USA
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Khuzema Mohsin
Khuzema Mohsin
Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana, USA
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Dominique Monlezun
Dominique Monlezun
Tulane University School of Medicine, New Orleans, Louisiana, USA
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Emad Kandil
Emad Kandil
Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana, USA
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more aggressive phenotypes of PTC with more prevalent extrathyroidal extension (ETE) and LN metastasis [ 9 , 10 ]. Tumors with BRAFV600E mutation also show a higher risk of disease persistence and recurrence [ 9 , 11 , 12 ]. As a prognostic factor
Yuwei Liu
Yuwei Liu
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Shengcai Wang
Shengcai Wang
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Yanzhen Li
Yanzhen Li
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Xuexi Zhang
Xuexi Zhang
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Zhiyong Liu
Zhiyong Liu
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Qiaoyin Liu
Qiaoyin Liu
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Nian Sun
Nian Sun
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Jie Zhang
Jie Zhang
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Wentong Ge
Wentong Ge
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Yongli Guo
Yongli Guo
Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Yuanhu Liu
Yuanhu Liu
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Xiaolian Fang
Xiaolian Fang
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Tingting Ji
Tingting Ji
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Jun Tai
Jun Tai
Children’s Hospital Capital Institute of Pediatrics, Department of Otolaryngology, Head and Neck Surgery, Beijing, China
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Xin Ni
Xin Ni
Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health (NCCH), Beijing, China
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types of cancer, well-differentiated thyroid cancer is the only malignancy to include age as a part of the American Joint Committee on Cancer staging system, indicating that age at diagnosis has been identified as a major determinant of thyroid cancer
Luigino Dal Maso
Luigino Dal Maso
Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
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Daniela Pierannunzio
Daniela Pierannunzio
National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy
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Silvia Francisci
Silvia Francisci
National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy
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Angela De Paoli
Angela De Paoli
Epidemiological Department, Azienda Zero, Padova, Italy
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Federica Toffolutti
Federica Toffolutti
Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
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Salvatore Vaccarella
Salvatore Vaccarella
Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France
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Silvia Franceschi
Silvia Franceschi
Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
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Rossella Elisei
Rossella Elisei
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Ugo Fedeli
Ugo Fedeli
Epidemiological Department, Azienda Zero, Padova, Italy
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of the DEPTH Working Group
of the DEPTH Working Group
of the DEPTH Working Group
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radioactive iodine treatment for pediatric and young adulthood differentiated thyroid cancer and risk of second primary malignancies . Journal of Clinical Oncology 2022 40 1439 – 1449 . ( https://doi.org/10.1200/JCO.21.01841 )
Sang-Hyeon Ju
Sang-Hyeon Ju
Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea
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Yong Bae Ji
Yong Bae Ji
Department of Otolaryngology–Head and Neck Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea
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Minchul Song
Minchul Song
Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea
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Joung Youl Lim
Joung Youl Lim
Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea
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Da Beom Heo
Da Beom Heo
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
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Min-Gyu Kim
Min-Gyu Kim
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
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Jae Won Chang
Jae Won Chang
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Ho-Ryun Won
Ho-Ryun Won
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea
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Yea Eun Kang
Yea Eun Kang
Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea
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Eu Jeong Ku
Eu Jeong Ku
Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Republic of Korea
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Mijin Kim
Mijin Kim
Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea
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Eun Kyung Lee
Eun Kyung Lee
Department of Internal Medicine, Center for Thyroid Cancer, National Cancer Center, Goyang-si, Republic of Korea
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June Young Choi
June Young Choi
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea
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Hyeong Won Yu
Hyeong Won Yu
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea
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Young Joo Park
Young Joo Park
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
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Jun-Ho Choe
Jun-Ho Choe
Division of Endocrine Surgery, Department of Surgery, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea
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Bon Seok Koo
Bon Seok Koo
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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the MASTER study group †
the MASTER study group
the MASTER study group †
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Introduction Thyroid cancer, which is the most common endocrine malignancy, has been increasing globally ( 1 , 2 ). From 1990 to 2017, the annual age-standardized incidence rate (ASIR) of thyroid cancer worldwide increased from 2.11 to 3
Ilaria Muller
Ilaria Muller
Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom
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Carla Moran
Carla Moran
Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom
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Beatriz Lecumberri
Beatriz Lecumberri
Department of Endocrinology and Nutrition, La Paz University Hospital, IdiPAZ, Autonomous University of Madrid, Madrid, Spain
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Brigitte Decallonne
Brigitte Decallonne
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium
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Neil Robertson
Neil Robertson
Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom
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Joanne Jones
Joanne Jones
Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom
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Colin M. Dayan
Colin M. Dayan
Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom
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is observed in AIDS-associated cancers, but an increase is seen in other cancer types such as lung cancer and cervix carcinoma [ 66 , 67 ]. Overall, there is no evidence for an increased risk of thyroid malignancy after IRT. Due to the high
Henning Dralle
Henning Dralle
Department of General, Visceral and Vascular Surgery, University Hospital, Medical Faculty, University of Halle-Wittenberg, Halle/Saale, Germany
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, although this technology reliably permits prediction of recurrent laryngeal nerve function after the operation [ 48 ], and helps avoid bilateral vocal cord palsy by postponing completion of the other side in benign goiter and low-risk differentiated thyroid
Syed Ali Imran
Syed Ali Imran
Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada
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Karen Chu
Karen Chu
Department of Oncology, University of Alberta, Edmonton, Alberta, Canada
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Murali Rajaraman
Murali Rajaraman
Department of Radiation Oncology, Dalhousie University, Halifax, Nova Scotia, Canada
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Drew Rajaraman
Drew Rajaraman
Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada
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Sunita Ghosh
Sunita Ghosh
Department of Oncology, University of Alberta, Edmonton, Alberta, Canada
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Sarah De Brabandere
Sarah De Brabandere
Department of Diagnostic Imaging, Western University, London, Ontario, Canada
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Stephanie M. Kaiser
Stephanie M. Kaiser
Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada
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Stan Van Uum
Stan Van Uum
Department of Medicine, Western University, London, Ontario, Canada
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Introduction Well-differentiated thyroid cancer (TC) is the most common thyroid malignancy, comprising over 90% of all TC [ 1 ]. Furthermore, data from various countries including Canada [ 2 ], the USA [ 3 - 5 ], and European countries [ 6 - 8
Simon H.S. Pearce
Simon H.S. Pearce
Institute of Genetic Medicine, Newcastle University
Royal Victoria Infirmary, Newcastle upon Tyne, UK
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Royal Victoria Infirmary, Newcastle upon Tyne, UK
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Georg Brabant
Georg Brabant
Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany
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Leonidas H. Duntas
Leonidas H. Duntas
Endocrine Unit, Evgenidion Hospital, University of Athens, Athens, Greece
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Fabio Monzani
Fabio Monzani
Department of Clinical and Experimental Medicine, Università di Pisa, Pisa, Italy
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Robin P. Peeters
Robin P. Peeters
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Salman Razvi
Salman Razvi
Institute of Genetic Medicine, Newcastle University
Queen Elizabeth Hospital, Gateshead, UK
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Queen Elizabeth Hospital, Gateshead, UK
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Jean-Louis Wemeau
Jean-Louis Wemeau
Clinique Endocrinologique Marc Linquette, CHU, Lille, France
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within the normal range are associated with an increased risk of thyroid cancer [reviewed in [ 40 ], [ 41 ]]. This was first proposed in a cohort of 1,500 subjects by Boelaert et al. [ 42 ] when studying the frequency of malignancy in patients with
Marta Amaro da Silveira Duval
Marta Amaro da Silveira Duval
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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André Borsatto Zanella
André Borsatto Zanella
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Ana Patrícia Cristo
Ana Patrícia Cristo
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Carlo Sasso Faccin
Carlo Sasso Faccin
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Marcia Silva Graudenz
Marcia Silva Graudenz
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Ana Luiza Maia
Ana Luiza Maia
Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Introduction Differentiated thyroid cancer (DTC) is the most common endocrine cancer, accounting for approximately 90% of the thyroid gland malignancies [ 1 ]. DTC prevalence has risen in the last decades, mainly due to the papillary subtype
Shi Hui Junice Wong
Shi Hui Junice Wong
Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore
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the draining cervical lymph nodes. Given the paucity of data regarding this phenomenon, other more common concomitant pathologies giving rise to lymphadenitis (such as malignancies and infections) need to be excluded. The patient in this report had
