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Yalin Iscan Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

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Ismail Cem Sormaz Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

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Fatih Tunca Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

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Yasemin Giles Senyurek Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

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ipsilateral prophylactic central neck dissection (CND) which included prelaryngeal, pretracheal, and ipsilateral paratracheal ­regions. The remaining 15 (23.5%) patients had enlarged lateral cervical lymph nodes which proved to be metastatic by FNAB cytology

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Carolina C.P.S. Janovsky Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Rui M.B. Maciel Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Cleber P. Camacho Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Rosalia P. Padovani Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Claudia C. Nakabashi Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Ji H. Yang Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Eduardo Z. Malouf Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Elza S. Ikejiri Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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M. Conceição O.C. Mamone Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Jairo Wagner Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Danielle M. Andreoni Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Rosa Paula M. Biscolla Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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de Ensino e Pesquisa Albert Einstein (in São Paulo, Brazil). From these 2,007 patients, 550 with differentiated thyroid cancer underwent TT by the same surgical team based on the diagnosis of suspicious or malignant fine needle aspiration cytology

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X Y Hu Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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J Wu Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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P Seal EFW Radiology, Calgary, Alberta, Canada

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S A Ghaznavi Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Department of Medicine, Section of Endocrinology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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C Symonds Department of Medicine, Section of Endocrinology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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S Kinnear Department of Medicine, Section of Endocrinology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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R Paschke Department of Medicine, Section of Endocrinology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Departments of Medicine, Oncology, Pathology and Laboratory Medicine, Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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9.8–19.4 ( 10 , 11 , 12 , 13 ). Studies like these further illustrate the value of high-quality TUS reports. Additionally, with the predictive values reported above, it is feasible that the combination of TUS, molecular analysis, and cytology can

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Darshan Patil Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Abhay Kumaraswamy Kattepur Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Srinivas Kodaganur Gopinath Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Shivanand Swamy Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Amarendra Shankarappa Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Gopinath Kodaganur Srinivasachar Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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in both the lobes. She was clinically euthyroid. X-ray of the left digit showed multiple lytic lesions in the terminal phalanx. Fine-needle aspiration cytology (FNAC) of the thyroid revealed follicular carcinoma. Biopsy from the growth in the little

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Santiago Tofé Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain

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Iñaki Argüelles Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain

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Ana Forteza Department of Pathology, University Hospital Son Espases, Palma de Mallorca, Spain

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Cristina Álvarez Department of Surgery, Section of Endocrine Surgery, University Hospital Son Espases, Palma de Mallorca, Spain

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Alessandra Repetto Department of Nuclear Medicine, University Hospital Son Espases, Palma de Mallorca, Spain

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Luis Masmiquel Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain

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Irene Rodríguez Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain

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Eladio Losada Department of Endocrinology, Hospital Can Misses, Ibiza, Spain

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Nuria Sukunza Department of Endocrinology, Hospital de Manacor, Manacor, Spain

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María Cabrer Department of Endocrinology, Hospital Comarcal de Inca, Inca, Spain

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Mildred Sifontes Department of Pathology, Hospital Mateu Orfila, Menorca, Spain

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María del Mar del Barrio Department of Pathology, Hospital Mateu Orfila, Menorca, Spain

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Antonia Barceló Department of Laboratory, University Hospital Son Espases, Palma de Mallorca, Spain

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Álvaro Tofé Department of Maxillofacial Surgery, Hospital Puerta del Mar, Cádiz, Spain

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Vicente Pereg Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain

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cytology (FNAC) by clinicians at Endocrinology Departments, as a potential cause of overdiagnosis. Material and methods We conducted a combined retrospective review of electronic health records from Pathology, Surgery, Endocrinology, and Nuclear

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Jan Jiskra 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jiří Horáček 4th Department of Medicine, Faculty of Medicine, Charles University, University Hospital Hradec Králové, Czech Republic

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Sylvie Špitálníková Department of Nuclear Medicine, District Hospital, Havlíčkův Brod, Czech Republic

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Jan Paleček 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Zdeňka Límanová 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jan Krátký 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Drahomíra Springer Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Kristýna Žabková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Hana Vítková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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, and/or (iii) any assisted reproduction technique used. GDM was defined as a medical record about its presence during a previous and/or current pregnancy. Thyroid ultrasound and fine-needle aspiration cytology In women included in the study, one

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Laura Agate Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Francesca Bianchi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Federica Brozzi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Pierina Santini Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Eleonora Molinaro Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Valeria Bottici Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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David Viola Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Loredana Lorusso Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Paolo Vitti Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Rossella Elisei Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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by fine-needle aspiration cytology. Therefore, only 6/545 (1.1%) cases (3 LR [0.87%] and 3 IR [1.5%]) showed metastases (1 cervical and 1 mediastinal lymph node, 3 lung and 1 bone metastatic lesions) documented by ptWBS only. None of the patients with

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Francisco Sousa Santos Endocrinology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Rita Joana Santos Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Faculty of Medical Sciences of Lisbon, Lisbon, Portugal

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. We considered the following inclusion criteria: adult patients (≥18 years of age) with the diagnosis of metastatic DTC (as confirmed by histological analysis of thyroidectomy specimens or by cytological findings in the case of patients who did not

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Hai-Yan Jia Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Juan Chen Department of Ultrasound, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China

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Zi-Xin Zhai Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Wen-Wen Fan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Si-Jie Yuan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Qiong Liu Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Xiao-Hui Yan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Qian-Qian Shen Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Li-Ping Liu Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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performed, considering the more invasive nature and the location of several nerves and vascular structures around the thyroid gland. According to the current guidelines, CNB is recommended for thyroid nodules with repeated inadequate FNA cytology, repeated

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Gilles Russ Thyroid and Endocrine Tumors, Institute of Endocrinology, Pitié Salpêtrière Hospital, Pierre and Marie Curie University, Paris, France

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Steen J. Bonnema Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Murat Faik Erdogan Department of Endocrinology and Metabolism, University of Ankara School of Medicine, İbni Sina Hastanesi, Ankara, Turkey

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Cosimo Durante Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy

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Rose Ngu Head Neck and Thyroid Imaging, Department of Radiology, Guy’s and St Thomas’ Hospitals NHS Foundation Trust, London, United Kingdom

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Laurence Leenhardt Thyroid and Endocrine Tumors, Institute of Endocrinology, Pitié Salpêtrière Hospital, Pierre and Marie Curie University, Paris, France

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cytological result, FNA should be repeated within 3 months to reduce the rate of false-negative samples. In case of subcentimeter nodules with high-risk US features, active surveillance is recommended, provided that there are no abnormal lymph nodes and the

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