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Furio Pacini Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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‘In the sub-categories of both primary intraglandular (thyroid) carcinoma… and primary extraglandular carcinoma… the presence of pathologically defined lymph nodes ameliorated the prognosis. Furthermore, the greater the number of lymph node

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Germán A. Jimenez Londoño Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Ana Maria Garcia Vicente Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Julia Sastre Marcos Department of Endocrinology, Complejo Hospitalario de Toledo, Toledo, Spain

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Francisco Jose Pena Pardo Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Mariano Amo-Salas Department of Mathematics, University of Castilla-La Mancha, Ciudad Real, Spain

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Manuel Moreno Caballero Department of Nuclear Medicine, Hospital Universitario Infanta Cristina Badajoz, Badajoz, Spain

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Maria Prado Talavera Rubio  Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Beatriz Gonzalez Garcia Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Niletys Dafne Disotuar Ruiz Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Angel Maria Soriano Castrejón Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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differentiated thyroid cancer. Best Pract Res Clin Endocrinol Metab 2013; 27: 701–712. 19 Latrofa F, Ricci D, Montanelli L, Rocchi R, Piaggi P, Sisti E, et al: Thyroglobulin autoantibodies in patients with papillary thyroid carcinoma: comparison of

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Giacomo Sturniolo Department of Human Pathology of the Adult and Developmental Age “G. Barresi”

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Carles Zafon Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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Mariacarla Moleti Department of Experimental Medicine, University of Messina, Messina, Italy

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Josep Castellví Department of Pathology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

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Francesco Vermiglio Department of Experimental Medicine, University of Messina, Messina, Italy

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Jordi Mesa Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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outcome than males. Indeed, different cohort studies reported a better “overall” and “disease-specific” survival, and fewer relapses in women than in men. Specifically concerning papillary thyroid carcinoma (PTC), although the overall outcome seems

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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia,” Udine

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Andrea Frasoldati Division of Endocrinology, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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papillary cancer, and neck recurrences of papillary thyroid cancer [ 32 , 33 ]. Conclusions Scientific societies should make guidelines easier to use and more readily transferable to clinical practice. Efforts should be made to introduce the use of

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Ayanthi Wijewardene Department of Endocrinology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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Matti Gild Department of Endocrinology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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Carolina Nylén Endocrine Surgery Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Geoffrey Schembri Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Nuclear Medicine Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Paul Roach Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Nuclear Medicine Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Jeremy Hoang Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Nuclear Medicine Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Ahmad Aniss Endocrine Surgery Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Anthony Glover Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Endocrine Surgery Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Mark Sywak Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Endocrine Surgery Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Stan Sidhu Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
Endocrine Surgery Department, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Diana Learoyd Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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Bruce Robinson Department of Endocrinology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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Lyndal Tacon Department of Endocrinology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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Roderick Clifton-Bligh Department of Endocrinology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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VA , Mandel SJ , Steward DL , . The prognostic significance of nodal metastases from papillary thyroid carcinoma can be stratified based on the size and number of metastatic lymph nodes, as well as the presence of extranodal extension . Thyroid

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Julia Ramalho Amalio da Silva Breder Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Paulo Alonso Garcia Alves Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Lucio Araújo Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Barbara Pires Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Priscila Valverde Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Daniel Alves Bulzico Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Andrade Accioly Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Rossana Corbo Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Papillary thyroid carcinoma 77 97.5  Hurthle thyroid carcinoma 2 2.5 Tumor size (cm), n   = 76 2.8 ± 1.4 – 2.65 (0.5–7; 2.0–3.4) Extra-thyroidal extension, n   = 76  Yes 50 64.1  No 28 35

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Fabián Pitoia Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Fernando Jerkovich Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Anabella Smulever Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Gabriela Brenta Division of Endocrinology, Dr. César Milstein Hospital, Buenos Aires, Argentina

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Fernanda Bueno Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Graciela Cross Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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of papillary thyroid carcinoma (70.1%), were female (87.3%), and were AJCC stage I (59.0%). The median follow-up in the whole cohort was 74.3 months (range: 36.1-317.9; mean 92.8 ± 3.3). Patients were classified as having low (54.5%), intermediate (23

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Laura Agate Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Francesca Bianchi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Federica Brozzi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Pierina Santini Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Eleonora Molinaro Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Valeria Bottici Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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David Viola Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Loredana Lorusso Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Paolo Vitti Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Rossella Elisei Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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papillary thyroid carcinoma (PTC); (b) the diagnostic purpose due to the possibility to perform a post-RRA whole-body scan (ptWBS) to identify additional sites of disease not identified before the RRA [ 2 - 4 ]; and (c) the facilitator purpose because the

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Kirsten E. Stewart Department of Head and Neck Surgery, St John’s Hospital at Howden, Livingston, United Kingdom

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Mark W.J. Strachan Metabolic Unit, Western General Hospital, Edinburgh, United Kingdom

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Devraj Srinivasan Department of Oncology, Western General Hospital, Edinburgh, United Kingdom

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Morna MacNeill Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

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Lucy Wall Department of Oncology, Western General Hospital, Edinburgh, United Kingdom

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Iain J. Nixon Department of Head and Neck Surgery, St John’s Hospital at Howden, Livingston, United Kingdom

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papillary carcinoma of the thyroid with airway invasion based on the anatomic manner of extension to the trachea: a clinicopathologic study based on 22 patients who underwent thyroidectomy and airway resection . Hum Pathol . 1993 Aug ; 24 ( 8 ): 866 – 70

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Francesco Quaglino General Surgery Unit, Turin, Italy

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Valentina Marchese General Surgery Unit, Turin, Italy

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Enrico Mazza Endocrinology and Metabolism Unit, Turin, Italy

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Cristina Gottero Endocrinology and Metabolism Unit, Turin, Italy

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Riccardo Lemini General Surgery Unit, Turin, Italy

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Stefano Taraglio Pathology Unit, Maria Vittoria Hospital ASL TO2, Turin, Italy

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/trabecular arrangement, with scant or absent colloid; - samples composed exclusively or almost exclusively of Hürthle cells [ 10 ]; - samples characterized by nuclear alterations suggestive of papillary carcinoma, but too mild or focal to be included in the TIR-4

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