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Introduction Thyroid hormones play an essential role in regulating metabolic functions in humans. The fine-tuning of thyroid hormone metabolism at tissue level is made by the widely expressed iodothyronine deiodinase enzymes, which activate
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea
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Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Introduction Thyroid cancer, which is the most common endocrine malignancy, has been increasing globally ( 1 , 2 ). From 1990 to 2017, the annual age-standardized incidence rate (ASIR) of thyroid cancer worldwide increased from 2.11 to 3
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Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy
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Introduction Nodular thyroid disease is a common finding, especially in females and in the elderly population. Thyroid nodules are found in 5% of the general population with the use of palpation [ 1 ], but high-resolution ultrasonography (US
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What Is Known about This Topic • Primary thyroid gland lymphomas (PTLs) are uncommon tumors. • Small lymphocytic lymphoma (SLL) is the least common type of thyroid lymphomas. • SLL type of PTL revealing plasmacytic differentiation has
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Introduction Pregnancy is a condition leading to an increased demand in thyroid hormones (TH), resulting from the fetal need (especially before 18–20 weeks), increased renal iodide loss, increased levels of serum thyroxine-binding globulin
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, with a daily dissociation rate of iodine from the drug of about 10%) and pharmacological properties (inhibition of peripheral monodeiodination of thyroxine, T 4 ), the drug causes changes in thyroid function tests and may be responsible for thyroid
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Introduction Differentiated thyroid cancer patients are monitored for local or distant recurrence after total thyroidectomy. They typically undergo physical examination, serial measurement of serum thyroglobulin (Tg) levels, and serial
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Methods of Development of Evidence-Based Guidelines The European Thyroid Association (ETA) Executive Committee launched a taskforce to produce guidelines on the treatment of metastatic medullary thyroid cancer (MTC). A chairperson was selected
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Department of Medicine, University of Alcalá de Henares, Madrid
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IdiSNA (Instituto de investigación en la salud de Navarra), Pamplona, Spain
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care resources and the wide use of periodic medical check-ups have led to the frequent diagnosis of thyroid nodules in many individuals who live in developed countries. There are no 2 identical thyroid nodules in the same way as there are no 2 identical
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan
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Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan
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Introduction Abnormal 18F–fluorodeoxyglucose (FDG) accumulation in the thyroid gland is observed in 5% of patients ( 1 , 2 , 3 ). The standardized uptake value (SUV) and pattern of accumulation (focal, diffuse, and diffuse-plus-focal) are