Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
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aspiration of thyroid. Arch Pathol Lab Med 2001;125:484–488. 11260620 4 Boyd LA, Earnhardt RC, Dunn JT, Frierson HF, Hanks JB: Preoperative evaluation and predictive value of fine-needle aspiration and frozen section of thyroid nodules. J Am Coll Surg
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increased [ 2 ]. Thyroid cancer is present in approximately 5% of nodules, even though rates as high as 15% have been reported [ 1 , 3 , 4 ]. Fine needle aspiration biopsy is the clinical procedure of choice for evaluating whether a nodule is benign or
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Departments of Biopathology, Centre François Baclesse, Caen, France
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Introduction Fine needle aspiration (FNA) cytology of thyroid nodules is considered as the key tool to distinguish between benign and malignant tumors [ 1 ]. However, FNA cytology is classified as indeterminate in approximately 20–30% of
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Santa Casa de São Paulo, São Paulo, Brazil
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Fleury Medicina e Saúde, São Paulo, Brazil
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Fleury Medicina e Saúde, São Paulo, Brazil
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used to distinguish between benign and malignant lesions [ 3 , 4 ]. In general, a cytological analysis with fine-needle aspiration (FNA) under US guidance is recommended for nodules with intermediate or highly suspicious sonographic patterns and with
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]. The goal of an initial sonographic assessment of thyroid nodules is to distinguish benign nodules that can be managed conservatively from those with suspicious or malignant features requiring further management. Fine needle aspiration (FNA) plays a
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sensitivity and specificity of the technique [ 4 ], and makes it possible to take samples of the solid areas in cystic lesions. Despite fine-needle aspiration cytology (FNAC) being almost universally used to take thyroid samples and, accordingly, there being
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What Is Known about This Topic So Far? • Although many authors recommend a core-needle biopsy as an alternative modality in cases of inconclusive cytology with fine-needle aspiration for thyroid nodule, it is not in the American Thyroid
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(hypoechoic with irregular margins or microcalcifications/rim calcifications with a small extrusive soft tissue component or taller than wide shape [ 5 , 6 ]) were, until recently, submitted to US-guided fine-needle aspiration. Cases with cytology suspicious
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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, 3 , 4 , 5 , 6 , 7 ). Thyroid ultrasound-guided fine needle aspiration cytology (FNAC) can be a noninvasive and useful tool to confirm the diagnosis and prevent unnecessary transcranial biopsy ( 3 , 8 ). Here we present the case of a young
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are the standards for US examination, US-guided fine-needle aspiration (US-FNA) techniques, and reports? - Can US differentiate between benign and pathological cervical LN and lesions in the thyroid bed? - When should neck US be performed? - What