José I. López
José I. López
Department of Pathology, Cruces University Hospital, BioCruces Research Institute, University of the Basque Country, Barakaldo
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Rosa Zabala
Rosa Zabala
Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain
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José Luís del Cura
José Luís del Cura
Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain
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sensitivity and specificity of the technique [ 4 ], and makes it possible to take samples of the solid areas in cystic lesions. Despite fine-needle aspiration cytology (FNAC) being almost universally used to take thyroid samples and, accordingly, there being
Eun Kyung Jang
Eun Kyung Jang
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Dong Eun Song
Dong Eun Song
Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea
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Gyungyub Gong
Gyungyub Gong
Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea
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Jung Hwan Baek
Jung Hwan Baek
Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
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Yun Mi Choi
Yun Mi Choi
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Min Ji Jeon
Min Ji Jeon
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Ji Min Han
Ji Min Han
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Won Gu Kim
Won Gu Kim
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Tae Yong Kim
Tae Yong Kim
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Young Kee Shong
Young Kee Shong
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Won Bae Kim
Won Bae Kim
Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea
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Introduction Fine needle aspiration (FNA) is a rapid, cost-effective, and safe test, which is widely used for the diagnosis of thyroid nodules [ 1 ]. The positive predictive value of a malignant FNA cytology (FNAC) result is 97-99% according
Shaodong Hou
Shaodong Hou
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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Yiceng Sun
Yiceng Sun
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Zeyu Yang
Zeyu Yang
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Mi Tang
Mi Tang
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Tingjie Yin
Tingjie Yin
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Cong Shao
Cong Shao
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Cunye Yan
Cunye Yan
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Linlong Mo
Linlong Mo
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Yuquan Yuan
Yuquan Yuan
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Supeng Yin
Supeng Yin
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
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Fan Zhang
Fan Zhang
Department of Breast and Thyroid Surgery, Chongqing General Hospital, Chongqing, China
Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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LNs before or during surgery, which would help surgeons choose the appropriate surgical scope and prevent over- or undertreatment. Neck ultrasonography (US) and US-guided fine needle aspiration cytology (FNAC) are routinely used for LNM screening
Mathieu Bergeron
Mathieu Bergeron
Department of Otolaryngology - Head and Neck Surgery, Laval University, Quebec, Que., Canada
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Danielle Beaudoin
Danielle Beaudoin
Enfant-Jésus Hospital, Quebec, Que., Canada
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What Is Known about This Topic So Far? • Although many authors recommend a core-needle biopsy as an alternative modality in cases of inconclusive cytology with fine-needle aspiration for thyroid nodule, it is not in the American Thyroid
Maria Mavromati
Maria Mavromati
Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Verdiana Caironi
Verdiana Caironi
Department of Internal Medicine, Lugano Regional Hospital, Ente Ospedaliero Cantonale, Via Tesserete Lugano, Switzerland
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Essia Saiji
Essia Saiji
Department of Pathology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Maria-Isabel Vargas
Maria-Isabel Vargas
Department of Neuroradiology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Shahan Momjian
Shahan Momjian
Department of Neurosurgery, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Stephanie Andrade-Lopes
Stephanie Andrade-Lopes
Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
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Capucine Gubert
Capucine Gubert
Department of Internal Medicine, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
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Marco Stefano Demarchi
Marco Stefano Demarchi
Department of Thoracic and Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
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Ismini Mainta
Ismini Mainta
Department of Nuclear Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
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François R Jornayvaz
François R Jornayvaz
Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Kaveh Samii
Kaveh Samii
Department of Hematology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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Grégoire Stalder
Grégoire Stalder
Service and Central Laboratory of Hematology, Lausanne University Hospital, rue du Bugnon Lausanne, Switzerland.
Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland
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Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland
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Sophie Leboulleux
Sophie Leboulleux
Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland
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, 3 , 4 , 5 , 6 , 7 ). Thyroid ultrasound-guided fine needle aspiration cytology (FNAC) can be a noninvasive and useful tool to confirm the diagnosis and prevent unnecessary transcranial biopsy ( 3 , 8 ). Here we present the case of a young
L. Leenhardt
L. Leenhardt
Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France
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M.F. Erdogan
M.F. Erdogan
Department of Endocrinology and Metabolism, University of Ankara School of Medicine, İbni Sina Hastanesi, Ankara, Turkey
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L. Hegedus
L. Hegedus
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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S.J. Mandel
S.J. Mandel
Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., USA
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R. Paschke
R. Paschke
Department of Endocrinology, University of Leipzig, Leipzig, Germany
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T. Rago
T. Rago
Endocrine Unit 1, Department of Internal Medicine, Ospedale Cisanello, University of Pisa, Pisa, Italy
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G. Russ
G. Russ
Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France
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are the standards for US examination, US-guided fine-needle aspiration (US-FNA) techniques, and reports? - Can US differentiate between benign and pathological cervical LN and lesions in the thyroid bed? - When should neck US be performed? - What
Alessia Cozzolino
Alessia Cozzolino
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Tiziana Filardi
Tiziana Filardi
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Ilaria Simonelli
Ilaria Simonelli
Service of Medical Statistics and Information Technology, Fatebenefratelli Foundation for Health Research and Education, Rome, Italy
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Giorgio Grani
Giorgio Grani
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Camilla Virili
Camilla Virili
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Ilaria Stramazzo
Ilaria Stramazzo
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Maria Giulia Santaguida
Maria Giulia Santaguida
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Pietro Locantore
Pietro Locantore
Endocrinology Unit, Fondazione Policlinico Universitario Agostino Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Massimo Maurici
Massimo Maurici
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Daniele Gianfrilli
Daniele Gianfrilli
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Andrea M Isidori
Andrea M Isidori
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Cosimo Durante
Cosimo Durante
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Carlotta Pozza
Carlotta Pozza
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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on behalf of TALENT Group
on behalf of TALENT Group
on behalf of TALENT Group
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children should be the same as in adults with a few exceptions. In particular, clinical context and US characteristics should be used rather than size to identify nodules that warrant fine-needle aspiration (FNA), because the use of nodule size as a
Meenu Gill
Meenu Gill
Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak
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Ashima Batra
Ashima Batra
Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak
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Ashok Sangwaiya
Ashok Sangwaiya
Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak
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Samta Shakya
Samta Shakya
General Hospital, Sirsa, India
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Sumiti Gupta
Sumiti Gupta
Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak
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Rajeev Sen
Rajeev Sen
Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak
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cervical lymph node obtained during fine-needle aspiration revealed a similar appearance with a predominant cell population of small- to medium-sized cells revealing paracentral to eccentric nuclei with clock-face chromatin and abundant sky-blue cytoplasm
Yalin Iscan
Yalin Iscan
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
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Ismail Cem Sormaz
Ismail Cem Sormaz
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
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Fatih Tunca
Fatih Tunca
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
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Yasemin Giles Senyurek
Yasemin Giles Senyurek
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
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ultrasonography (US) and the widespread use of fine-needle aspiration biopsy (FNAB) provided to identify PMC preoperatively [ 1 , 3 ]. In autopsy studies, the pathological detection rate of clinically occult papillary carcinoma has been in the range of 5.6 to
Sravanthi Nagavalli
Sravanthi Nagavalli
Division of Endocrinology and Metabolism, Torrance, CA, USA
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Marelle Yehuda
Marelle Yehuda
Division of Endocrinology and Metabolism, Torrance, CA, USA
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Laron W. McPhaul
Laron W. McPhaul
Department of Pathology and Laboratory Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA
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Andrew G. Gianoukakis
Andrew G. Gianoukakis
Division of Endocrinology and Metabolism, Torrance, CA, USA
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What Is Known about This Topic? • Cervical schwannomas can mimic thyroid nodules and are historically difficult to diagnosis preoperatively due to the low diagnostic yield of fine needle aspiration and their appearance as hypoechoic lesions on
