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Zhaoqi Zhang Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria
Department of Nuclear Medicine, The Fourth hospital of Hebei Medical University, Shijiazhuang, Hebei, China

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Josef Yu Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Eva Rainer Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Vienna, Austria

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Lindsay Hargitai Department of General Surgery, Medical University of Vienna, Vienna, Austria

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Zewen Jiang Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Georgios Karanikas Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Tatjana Traub-Weidinger Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Richard Crevenna Department of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Vienna, Austria.

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Marcus Hacker Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Shuren Li Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Introduction Medullary thyroid cancer (MTC) accounts for about 2% of all thyroid cancers. About 20–25% of MTC cases are hereditary, caused by a mutation in the RET proto-oncogene. However, in most cases, MTC is sporadic with no underlying

Article Type:
Research Article
Collections:
Thyroid cancer - basic and translational
DOI:
https://doi.org/10.1530/ETJ-24-0089
Volume/Issue:
Volume 13: Issue 4
Open access
Marine Sitbon Pharmacy Department, Hospital Saint-Louis APHP, Paris, France

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Porhuoy Chou Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Seydou Bengaly Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Brigitte Poirot Department of Molecular Oncology, Saint-Louis Hospital (AP-HP), Université Paris Cité INSERM U 944, CNRS UMR 7212, Paris, France

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Marie Laloi-Michelin Department of Internal Medicine, Hospital Lariboisière APHP, Paris, France

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Laure Deville Pharmacy Department, Hospital Saint-Louis APHP, Paris, France

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Atanas Pachev Radiology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Ahouefa Kowo-Bille Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Clement Dumont Medical Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Cécile N Chougnet Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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metastatic medullary thyroid cancer. Case report/case presentation A woman, born in 1956, was diagnosed with sporadic MTC in 2005, for which she underwent complete thyroidectomy with bilateral central compartment and lateral compartment neck

Article Type:
Case Report
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-22-0032
Volume/Issue:
Volume 11: Issue 6
Open access
Francesca Orsolini Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Alessandro Prete Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Pierpaolo Falcetta Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Domenico Canale Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

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Greta Alì Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

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Francesca Manassero Division of Urology, Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Eleonora Molinaro Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Oncology 2010 22 475 – 485 . ( https://doi.org/10.1016/j.clon.2010.05.002 ) 3 Viola D Elisei R . Management of medullary thyroid cancer . Endocrinology and Metabolism Clinics of North America 2019 48 285 – 301 . ( https://doi.org/10.1016/j.ecl.2018

Article Type:
Case Report
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-21-0016
Volume/Issue:
Volume 11: Issue 2
Open access
Ségolène Hescot Department of Drug Development and Innovation (D3i), Institut Curie, Paris, France

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Julien Masliah-Planchon Department of Genetics, Institut Curie, Paris, France

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Pauline du Rusquec Department of Drug Development and Innovation (D3i), Institut Curie, Paris, France

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Célia Dupain Department of Drug Development and Innovation (D3i), Institut Curie, Paris, France

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Maud Kamal Department of Drug Development and Innovation (D3i), Institut Curie, Paris, France

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Vincent Servois Department of Radiology, Institut Curie, Paris, France

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Ivan Bieche Department of Genetics, Institut Curie, Paris, France

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.1016/S2213-8587(2100120-0 ) 7 Hedayati M Zarif Yeganeh M Sheikholeslami S Afsari F . Diversity of mutations in the RET proto-oncogene and its oncogenic mechanism in medullary thyroid cancer . Critical Reviews in Clinical Laboratory Sciences

Article Type:
Case Report
Collections:
Thyroid cancer - basic and translational
DOI:
https://doi.org/10.1530/ETJ-22-0044
Volume/Issue:
Volume 11: Issue 5
Open access
Zoe A. Efstathiadou Department of Endocrinology, “Hippokration” General Hospital of Thessaloniki, Thessaloniki, Greece

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Charalambos Tsentidis Department of Endocrinology, General Hospital of Nikaia “Agios Panteleimon”, Piraeus, Greece

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Alexandra Bargiota Department of Endocrinology, University of Thessaly, Larisa, Greece

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Vasiliki Daraki Department of Endocrinology, University Hospital of Crete, Heraklion, Greece

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Kalliopi Kotsa Department of Endocrinology, “Ahepa” Hospital, Aristotle University, Thessaloniki, Greece

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Georgia Ntali Department of Endocrinology, Diabetes and Metabolism, “Evangelismos” Hospital Athens, Athens, Greece

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Labrini Papanastasiou Department of Endocrinology and Diabetes Center, Athens General Hospital “G. Gennimatas”, Athens, Greece

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Stelios Tigas Department of Endocrinology, University of Ioannina, Ioannina, Greece

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Konstantinos Toulis Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece

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Kalliopi Pazaitou-Panayiotou Division of Endocrinology, Endocrine Oncology, Interbalkan Medical Center, Thessaloniki, Greece

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Maria Alevizaki Endocrine Unit, Department of Medical Therapeutics, School of Medicine, Kapodistrian University of Athens, Athens, Greece

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Introduction Medullary thyroid cancer (MTC) is a malignant tumor arising from the thyroid parafollicular C cells. It is considered a rare neoplasm since it accounts for just 1–2% of all thyroid cancers [ 1 , 2 ]. Prognosis depends on disease

Article Type:
Meta Analysis
DOI:
https://doi.org/10.1159/000509457
Volume/Issue:
Volume 10: Issue 2
Free access
Richard T. Kloos Divisions of Endocrinology, Diabetes and Metabolism, and Nuclear Medicine, Departments of Internal Medicine and Radiology, The Ohio State University, Columbus, Ohio, USA

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Introduction The European Thyroid Association (ETA) launched a taskforce, chaired by Martin Schlumberger, to create guidelines on the treatment of metastatic medullary thyroid cancer (MTC) [ 1 ]. The decision to create a focused guideline

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000337054
Volume/Issue:
Volume 1: Issue 1
Free access
Laura Fugazzola Department of Clinical Sciences and Community Health, University of Milan and Endocrine Unit, Fondazione IRCCS Ca' Granda, Milan, Italy

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Calcitonin, the Marker of Medullary Thyroid Cancer Medullary thyroid cancer (MTC) can be a very aggressive tumor. Significant differences in survival have been reported according to the stage of the tumor at the time of diagnosis, the survival

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000346020
Volume/Issue:
Volume 2: Issue 1
Free access
Luisa Paschke Department of Endocrinology and Nephrology, Division of Endocrinology, University Clinic Leipzig, Leipzig, Germany
Department of Endocrinology and Nephrology, Division of Nephrology, University Clinic Leipzig, Leipzig, Germany

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Thomas Lincke Department of Radiology, Division of Nuclear Medicine, University Clinic Leipzig, Leipzig, Germany

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Katja Sibylle Mühlberg Department of Angiology, University Clinic Leipzig, Leipzig, Germany

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Wolfram J. Jabs Department of Nephrology, Vivantes Clinics, Berlin, Germany

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Tom H. Lindner Department of Endocrinology and Nephrology, Division of Nephrology, University Clinic Leipzig, Leipzig, Germany

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Ralf Paschke Division of Endocrinology, University of Calgary, Calgary, Alberta, Canada

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drugs. Introduction Tyrosine kinase inhibitors (TKIs) have been approved as an important therapeutic option for the treatment of progressive, metastatic medullary thyroid cancer (MTC) and radioiodine refractory differentiated thyroid cancer

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000491387
Volume/Issue:
Volume 7: Issue 6
Free access
Thomas Karrasch Department of Internal Medicine III, Giessen University Hospital, Giessen

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Saskia M. Herbst Center for and Institute of Human Genetics, University of Regensburg, Regensburg, Germany

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Ute Hehr Center for and Institute of Human Genetics, University of Regensburg, Regensburg, Germany

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Andreas Schmid Department of Internal Medicine III, Giessen University Hospital, Giessen

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Andreas Schäffler Department of Internal Medicine III, Giessen University Hospital, Giessen

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What Is Known about This Topic? • The pathogenic effect of the p.Val804Met missense mutation of the RET proto-oncogene is well described in familial medullary thyroid cancer. In contrast, the clinical significance of the novel missense

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000443730
Volume/Issue:
Volume 5: Issue 1
Free access
Stacey A. Fedewa Surveillance and Health Services Research, American Cancer Society, Atlanta, Ga., USA

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Ahmedin Jemal Surveillance and Health Services Research, American Cancer Society, Atlanta, Ga., USA

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Amy Y. Chen Department of Otolaryngology, Emory University School of Medicine, Atlanta, Ga., USA

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have high cause-specific survival rates that, on average, exceed 95% [ 2 ]. Yet, there is subset of differentiated thyroid cancers (DTCs) that do not respond to traditional therapies and have worse outcomes. Furthermore, medullary thyroid cancers (MTCs

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000449379
Volume/Issue:
Volume 5: Issue 4
Free access