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  • carcinoembryonic antigen x
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Carla Gambale Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Alessandro Prete Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Chiara Romei Department of Diagnostic Imaging, Unit of Radiology, Pisa University Hospital, Pisa, Italy

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Alessandro Celi Department of Surgery, Medicine, Molecular Biology and Critical Care, Respiratory Pathophysiology Unit, Pisa University Hospital, Pisa, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Antonio Matrone Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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/inflammatory disease were described in this CT scan. CTN and carcinoembryonic antigen (CEA) values were 4280 ng/L and 40 µg/L, respectively. The patient started systemic treatment with selpercatinib in April 2021 at the initial dose of 160 mg/BID. CTN and CEA values

Article Type:
Case Report
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-24-0189
Volume/Issue:
Volume 13: Issue 5
Open access
Ilaria Muller Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Lucy S. Kilburn Institute of Cancer Research – Clinical Trials & Statistics Unit (ICR-CTSU), London, United Kingdom

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Peter N. Taylor Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Peter J. Barrett-Lee Academic Breast Department, Velindre Cancer Centre, Cardiff, United Kingdom

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Judith M. Bliss Institute of Cancer Research – Clinical Trials & Statistics Unit (ICR-CTSU), London, United Kingdom

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Paul Ellis Guy’s Hospital and King’s College, London, United Kingdom

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Marian E. Ludgate Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Colin M. Dayan Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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-positive (TPOAb+) versus TPOAb-negative (TPOAb–) patients in some [ 15 - 18 ] but not all [ 19 ] studies. Currently, no validated major blood prognostic markers for BC are available; carcinoembryonic antigen and cancer antigen 15.3 are the most used, but have

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000460246
Volume/Issue:
Volume 6: Issue 4
Free access
Zhaoqi Zhang Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria
Department of Nuclear Medicine, The Fourth hospital of Hebei Medical University, Shijiazhuang, Hebei, China

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Josef Yu Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Eva Rainer Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Vienna, Austria

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Lindsay Hargitai Department of General Surgery, Medical University of Vienna, Vienna, Austria

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Zewen Jiang Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Georgios Karanikas Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Tatjana Traub-Weidinger Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Richard Crevenna Department of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Vienna, Austria.

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Marcus Hacker Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Shuren Li Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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, early diagnosis of the primary tumor and metastases is essential for outcomes. Basal calcitonin (bCt) and carcinoembryonic antigen (CEA) can be used for diagnosis and follow-up of MTC. In case of increased bCt levels, a calcium stimulation test may be

Article Type:
Research Article
Collections:
Thyroid cancer - basic and translational
DOI:
https://doi.org/10.1530/ETJ-24-0089
Volume/Issue:
Volume 13: Issue 4
Open access
Camille Buffet Department of Thyroid Pathologies and Endocrine Tumors, AP-HP, Pitié-Salpêtrière Hospital, Groupe de Recherche Clinique n°16 Tumeurs Thyroïdiennes, Sorbonne Université, Paris, France
UMR9019, Genome Integrity and Cancers, CNRS, Villejuif, France

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Sophie Leboulleux Department of Nuclear Medicine and Endocrine Oncology, Gustave Roussy Institut, Villejuif, France

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Françoise Kraeber-Bodéré Nuclear Medicine Department, Université de Nantes, CHU de Nantes, CNRS, Inserm, CRCINA, Nantes, France
CHU Nantes/ICO, Saint-Herblain, France

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Caroline Bodet-Milin Nuclear Medicine Department, Université de Nantes, CHU de Nantes, CNRS, Inserm, CRCINA, Nantes, France
CHU Nantes/ICO, Saint-Herblain, France

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Laure Cabanes Department of Cardiology, APHP, Cochin Hospital, Paris, France
Université de Paris, Paris, France

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Anthony Dohan Radiology Department, Université de Paris, Paris, France
Department of Radiology, AP-HP, Hôpital Cochin, Paris, France

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Pascal Leprince Department of Thoracic and Cardiovascular Surgery, Sorbonne Université, AP-HP, Pitié-Salpêtrière Hospital, Paris, France

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Martin Schlumberger UMR9019, Genome Integrity and Cancers, CNRS, Villejuif, France
Department of Nuclear Medicine and Endocrine Oncology, Gustave Roussy Institute, Villejuif, France

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Olivier Huillard Université de Paris, Sorbonne Paris Cité, Paris, France
Department of Medical Oncology, AP-HP, Hôpital Cochin, Paris, France

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Lionel Groussin INSERM Unité 1016, CNRS UMR 8104, Institut Cochin, Paris, France
Université de Paris, Paris, France
Department of Endocrinology, AP-HP, Hôpital Cochin, Paris, France

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progressive rise in calcitonin (up to 945 pg/mL, normal value <10 pg/mL) and carcino-embryonic antigen (CEA) (up to 8.5 ng/mL, normal value <5 ng/mL) levels led to the diagnosis of costal metastases treated with external beam radiation and surgery, 8 years

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000517716
Volume/Issue:
Volume 10: Issue 6
Open access
José I. López Department of Pathology, Cruces University Hospital, BioCruces Research Institute, University of the Basque Country, Barakaldo

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Rosa Zabala Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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José Luís del Cura Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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with such small samples. However, a strong positive staining for calcitonin, chromogranin A and carcinoembryonic antigen, and a lack of staining with thyroglobulin clearly indicate the nature of the cancer. Cytological analysis of the transport medium

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000343825
Volume/Issue:
Volume 2: Issue 1
Free access
Minoru Kihara Departments of Surgery, Kobe, Japan

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Akira Miyauchi Departments of Surgery, Kobe, Japan

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Hiroshi Yoshida Research, Kuma Hospital, Kobe, Japan

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Osamu Yamada Departments of Surgery, Kobe, Japan

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Hiroo Masuoka Departments of Surgery, Kobe, Japan

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Tomonori Yabuta Departments of Surgery, Kobe, Japan

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Takuya Higashiyama Departments of Surgery, Kobe, Japan

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Mitsuhiro Fukushima Departments of Surgery, Kobe, Japan

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Yasuhiro Ito Departments of Surgery, Kobe, Japan

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Kaoru Kobayashi Departments of Surgery, Kobe, Japan

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Akihiro Miya Departments of Surgery, Kobe, Japan

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normal ranges. Her serum calcitonin level was 69.0 pg/ml, and her carcinoembryonic antigen level was 1.3 ng/ml. The calcium-loading test showed a clear response in serum calcitonin levels, with the basal and peak values being 59 and 440 pg

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000369134
Volume/Issue:
Volume 3: Issue 4
Free access
Elli Anagnostou Departments of Endocrinology, Alexandra General Hospital, Athens, Greece

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Antonios Polymeris Departments of Endocrinology, Alexandra General Hospital, Athens, Greece

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Georgios Morphopoulos Departments of Pathology, Alexandra General Hospital, Athens, Greece

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Alexios Travlos Departments of Endocrinology, Alexandra General Hospital, Athens, Greece

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Vassiliki Sarantopoulou Departments of Endocrinology, Alexandra General Hospital, Athens, Greece

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Irini Papaspyrou Departments of Pathology, Alexandra General Hospital, Athens, Greece

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carcinoembryonic antigen is normal (3.8 ng/ml, range 0-5). Thyroid peroxidase antibodies are elevated (112 IU/ml, normal level <35 IU/ml) and TG antibodies are normal (<20 IU/ml, normal level <40 IU/ml). Discussion SO is a highly specialized form of mature

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000448474
Volume/Issue:
Volume 5: Issue 3
Free access
Carles Zafon Department of Endocrinology, Hospital Vall d'Hebron, and Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona

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Juan J. Díez Department of Endocrinology and Nutrition, Hospital Ramón y Cajal
Department of Medicine, University of Alcalá de Henares, Madrid

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Juan C. Galofré Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain
IdiSNA (Instituto de investigación en la salud de Navarra), Pamplona, Spain

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David S. Cooper Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

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, Rohmer V, Chang CH, Sharkey RM, Goldenberg DM, Barbet J; French Endocrine Tumor Group: Survival improvement in patients with medullary thyroid carcinoma who undergo pretargeted anti-carcinoembryonic-antigen radioimmunotherapy: a collaborative study with

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000457793
Volume/Issue:
Volume 6: Issue 2
Free access
Grace Segall Eli Lilly and Company, Indianapolis, IN, USA

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Ravinder Singh Eli Lilly and Company, Indianapolis, IN, USA

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Min-Hua Jen Eli Lilly and Company, Indianapolis, IN, USA

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Isaac Sanderson Adelphi Real World, Bollington, UK

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Alex Rider Adelphi Real World, Bollington, UK

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Katie Lewis Adelphi Real World, Bollington, UK

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Urpo Kiiskinen Eli Lilly and Company, Indianapolis, IN, USA

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MTC 31 22  Yes 21 (68) 18 (82)  No 2 (6) 1 (5) a In patients with known date at initial diagnosis. BMI, body mass index; CEA, carcinoembryonic antigen; ECOG PS, European Cooperative Oncology Group performance

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0172
Volume/Issue:
Volume 13: Issue 1
Open access
Friederike Schütz Martin Luther University Halle-Wittenberg, Institute for Medical Epidemiology, Biostatistics and Informatics, Halle (Saale), Germany

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Christine Lautenschläger Martin Luther University Halle-Wittenberg, Institute for Medical Epidemiology, Biostatistics and Informatics, Halle (Saale), Germany

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Kerstin Lorenz Department of General, Visceral and Vascular Surgery, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany

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Johannes Haerting Martin Luther University Halle-Wittenberg, Institute for Medical Epidemiology, Biostatistics and Informatics, Halle (Saale), Germany

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utility of PET/CT with 18 F-DOPA and 18 F-FDG in persistent or recurrent medullary thyroid carcinoma: the importance of calcitonin and carcinoembryonic antigen cutoff. Eur J Nucl Med Mol Imaging 2017, DOI 10.1007/s00259-017-3759-4. 10.1007/s00259

Article Type:
Meta Analysis
DOI:
https://doi.org/10.1159/000481707
Volume/Issue:
Volume 7: Issue 1
Free access