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M Grussendorf Department of Internal Medicine, University Hospital, Düsseldorf, Germany

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I Ruschenburg MVZ Wagnerstibbe Center for Cytology and Pathology, Einbeck, Germany

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G Brabant Department of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, University of Manchester, Manchester, UK

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ultrasound (US) criteria and possibly fine-needle aspiration cytology (FNAC), malignancy rates may be overestimated and will not necessarily reflect the chances of a nodule being first diagnosed by palpation or imaging methods. On the other hand, ROM may as

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-22-0027
Volume/Issue:
Volume 11: Issue 4
Open access
Antonis Polymeris Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Christina Kogia Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Dimitrios Ioannidis Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Dimitrios Lilis Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Maria Drakou Department of Endocrinology, Metabolism and Diabetes Mellitus/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Nicoletta Maounis Department of Cytology/Sismanogleio-Amalia Fleming Hospital, Athens, Greece

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Loukas Kaklamanis Department of Pathology/Mediterraneo Hospital, Glyfada, Greece

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Sofia Tseleni-Balafouta First Department of Pathology/University of Athens, Medical School, Athens, Greece

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. Author Contributions A.P. was the supervising physician, was involved in planning, and supervised the work, C.K. collected the samples, processed the data, drafted the manuscript, and designed the figures. N.M. performed the cytological analysis, S

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000506767
Volume/Issue:
Volume 9: Issue 3
Free access
Kanhaiyalal Agrawal Departments of Nuclear Medicine, London, UK

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James Weaver Departments of King's College London, London, UK

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Fahim Ul-Hassan Departments of Nuclear Medicine, London, UK
Departments of Clinical PET Centre, King's College London, London, UK

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Jean-Pierre Jeannon Departments of Otorhinolaryngology Head and Neck Surgery, London, UK

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Ricard Simo Departments of Otorhinolaryngology Head and Neck Surgery, London, UK

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Paul Carroll Departments of Consultant Endocrinologist, London, UK

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Johnathan G. Hubbard Departments of Consultant Endocrine Surgeon, Guy's and St Thomas' NHS Foundation Trust, London, UK

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Ashish Chandra Departments of Histopathology/Cytology, London, UK

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Hosahalli Krishnamurthy Mohan Departments of Nuclear Medicine, London, UK
Departments of Clinical PET Centre, King's College London, London, UK

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was made by USG of the neck, FNA cytology (FNAC) or histopathology of the surgically resected specimen, where available. The prevalence of thyroid incidentalomas on 18 F-FDG PET or PET/CT and the rate of malignancy in focal uptake were assessed. The

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000431319
Volume/Issue:
Volume 4: Issue 2
Free access
Pedro Weslley Souza Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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-risk PMT, I believe that FNA should precede this decision. At our institution, nodules with highly suspicious features on ultrasonography (US) are always submitted to FNA (irrespective of size) and the latter is repeated when cytology is commenced [ 3 , 4

Article Type:
Letter
DOI:
https://doi.org/10.1159/000486671
Volume/Issue:
Volume 7: Issue 3
Free access
Ernesto Maddaloni Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy

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Silvia Irina Briganti Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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Anna Crescenzi Pathology Unit, Campus Bio-Medico University of Rome, Rome, Italy

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Giuseppina Beretta Anguissola Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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Eleonora Perrella Pathology Unit, Campus Bio-Medico University of Rome, Rome, Italy

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Chiara Taffon Pathology Unit, Campus Bio-Medico University of Rome, Rome, Italy

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Andrea Palermo Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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Silvia Manfrini Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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Paolo Pozzilli Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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Angelo Lauria Pantano Endocrinology and Diabetes Unit, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy

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inappropriately referring patients to surgery in case of indeterminate cytology [ 1 ]. The presence and pattern of nodular vascular signs are often considered among the US features to discriminate benign from malignant nodules [ 2 , 3 ]. Despite this widespread

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000509325
Volume/Issue:
Volume 10: Issue 4
Free access
Sravanthi Nagavalli Division of Endocrinology and Metabolism, Torrance, CA, USA

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Marelle Yehuda Division of Endocrinology and Metabolism, Torrance, CA, USA

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Laron W. McPhaul Department of Pathology and Laboratory Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA

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Andrew G. Gianoukakis Division of Endocrinology and Metabolism, Torrance, CA, USA

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ultrasound. What Does This Case Report Add? • The preoperative diagnosis of a cervical schwannoma was suspected by the use of magnetic resonance imaging (MRI) which led to additional specialized cytologic stains. We review the radiographic

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000454877
Volume/Issue:
Volume 6: Issue 4
Free access
Marco Marino Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Center for Genomic Research, Italy

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Maria Laura Monzani Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Giulia Brigante Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Katia Cioni Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Bruno Madeo Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Daniele Santi Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Antonino Maiorana Department of Diagnostic and Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Italy

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Stefania Bettelli Department of Diagnostic and Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Italy

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Valeria Moriondo Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Center for Genomic Research, Italy

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Elisa Pignatti Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Center for Genomic Research, Italy

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Lara Bonacini Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Cesare Carani Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy

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Vincenzo Rochira Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Azienda USL of Modena, Modena, Italy

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Manuela Simoni Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, Italy
Center for Genomic Research, Italy
Azienda USL of Modena, Modena, Italy

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of FNAB is limited by the occurrence of false-negative (FN) results and diagnosis belongs to the indeterminate cytological category (15-25%) [ 7 , 8 ], ancillary tests are required to improve diagnostic accuracy and patient treatment outcomes [ 7 , 8

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000430092
Volume/Issue:
Volume 4: Issue 2
Free access
Stamatina Ioakim CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus
Medical School, University of Milan, Milan, Italy

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Akheel A Syed Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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George Zavros CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus

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Michalis Picolos Alithias Endocrinology Centre, Nicosia, Cyprus

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Luca Persani Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Angelos Kyriacou CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus
Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Medical School, European University of Cyprus, Nicosia, Cyprus

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indicative of a benign nodule (U1–U2) should be regarded as reassuring not requiring fine-needle aspiration cytology (FNAC), unless the patient has a statistically high risk of malignancy’. AACE, American Association of Clinical Endocrinologists; ACE

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-22-0163
Volume/Issue:
Volume 11: Issue 6
Open access
Tayyab S. Khan Division of Endocrinology and Metabolism, McMaster University, Hamilton, Ontario, Canada

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Esha Sharma LMC Diabetes and Endocrinology, Brampton, Ontario, Canada

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Baldev Singh LMC Diabetes and Endocrinology, Brampton, Ontario, Canada

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Bikram Jammu LMC Diabetes and Endocrinology, Brampton, Ontario, Canada

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Amarinder Chadha LMC Diabetes and Endocrinology, Brampton, Ontario, Canada

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Divya Markanday LMC Diabetes and Endocrinology, Brampton, Ontario, Canada

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Yan Yan Wu Office of Public Health Studies, University of Hawai’i at Manoa, Honolulu, Hawaii, USA

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Harpreet S. Bajaj LMC Diabetes and Endocrinology, Brampton, Ontario, Canada
Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada

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decision making for surgery or clinical follow-up and is indicated as per guidelines in the evaluation of thyroid nodules [ 1 ]. Since the advent of the Bethesda classification [ 2 ], the rate of receiving a nondiagnostic cytology for thyroid FNAB stands

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000488451
Volume/Issue:
Volume 7: Issue 3
Free access
Kassia B. Reuters Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Maria C.O.C. Mamone Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Elsa S. Ikejiri Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Cleber P. Camacho Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Claudia C.D. Nakabashi Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Carolina C.P.S. Janovsky Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Ji H. Yang Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Danielle M. Andreoni Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Rosalia Padovani Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Santa Casa de São Paulo, São Paulo, Brazil

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Rui M.B. Maciel Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Felipe A.B. Vanderlei Head and Neck Division, Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Rosa P.M. Biscolla Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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used to distinguish between benign and malignant lesions [ 3 , 4 ]. In general, a cytological analysis with fine-needle aspiration (FNA) under US guidance is recommended for nodules with intermediate or highly suspicious sonographic patterns and with

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000488104
Volume/Issue:
Volume 7: Issue 3
Free access