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Carles Zafon Department of Endocrinology, Spain
Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain

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Juan Antonio Baena Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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Josep Castellví Department of Pathology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Spain

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Gabriel Obiols Department of Endocrinology, Spain
Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain

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Oscar Gonzalez Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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José Manuel Fort Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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Ramon Vilallonga Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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Enric Caubet Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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Manuel Armengol Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Spain

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Jordi Mesa Department of Endocrinology, Spain
Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain

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. Cancer 2012;118:5473-5480. 10.1002/cncr.27591 22517468 28 De Matos PS, Ferreira APC, Ward LS: Prevalence of papillary microcarcinoma of the thyroid in Brazilian autopsy and surgical series. Endocr Pathol 2006;17:165-173. 10.1385/EP:17

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Signe Buhl Gram Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jacob Høygaard Rasmussen Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jens Bentzen Department of Oncology, Herlev Hospital, Copenhagen University, Copenhagen, Denmark

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Giedrius Lelkaitis Department of Pathology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christian von Buchwald Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christoffer Holst Hahn Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Papillary Microcarcinoma of the Thyroid. Thyroid [Internet]. 2017 ;28(1):thy.2017.0227. Available from: http://online.liebertpub.com/doi/10.1089/thy.2017.0227 12 Leboulleux S , Tuttle RM , Pacini F , Schlumberger M . Papillary

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Sang-Hyeon Ju Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea

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Yong Bae Ji Department of Otolaryngology–Head and Neck Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea

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Minchul Song Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea

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Joung Youl Lim Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea

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Da Beom Heo Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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Min-Gyu Kim Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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Jae Won Chang Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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Ho-Ryun Won Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea

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Yea Eun Kang Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea

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Eu Jeong Ku Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Republic of Korea

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Mijin Kim Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea

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Eun Kyung Lee Department of Internal Medicine, Center for Thyroid Cancer, National Cancer Center, Goyang-si, Republic of Korea

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June Young Choi Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea

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Hyeong Won Yu Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea

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Young Joo Park Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Jun-Ho Choe Division of Endocrine Surgery, Department of Surgery, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea

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Bon Seok Koo Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
Department of Otorhinolaryngology–Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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the MASTER study group †
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critical element of AS because cervical LN metastasis is associated with a higher recurrence rate ( 14 , 15 ) and poorer survival rates in PTC patients, especially those aged ≥45 years ( 16 ). In patients with papillary thyroid microcarcinoma (PTMC

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Hao Li Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otorhinolaryngology, Tan Tock Seng Hospital, Singapore, Singapore

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Nir Livneh Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Ramat Gan, Israel

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Snjezana Dogan Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Ashok R. Shaha Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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] observation that most patients with synchronous MTC and PTC have papillary thyroid microcarcinoma while the MTC was >1 cm, and there was no difference in the rate of identifying PTC in patients treated surgically for MTC (19%), Grave’s disease (15%), and

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Toru Takano Rinku General Medical Center, Izumisano, Japan
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita, Japan
Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Japan

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number of them show rapid growth and become juvenile clinical cancer. The rest become PTMs. No case has been reported of a PTM becoming lethal or undergoing anaplastic transformation. PTM, papillary thyroid microcarcinoma. The other is our fetal

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Neslihan Kurtulmus Endocrinology and Thyroid Clinic, Acibadem Maslak Hospital, Istanbul, Turkey

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Burak Ertas Departments of Otorhinolaryngology, Istanbul, Turkey

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Yesim Saglican Pathology, Medical Faculty, Acibadem University, Istanbul, Turkey

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Hakan Kaya Endocrinology and Thyroid Clinic, Acibadem Maslak Hospital, Istanbul, Turkey

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Umit Ince Pathology, Medical Faculty, Acibadem University, Istanbul, Turkey

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Mete Duren Endocrinology and Thyroid Clinic, Acibadem Maslak Hospital, Istanbul, Turkey

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Introduction Papillary thyroid cancer (PTC) is the most common type of endocrine cancer [ 1 ]. It originates from follicular epithelial cells and usually has a slow progression with a good prognosis. However, of note, it presents with a high

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Chi-Yu Kuo Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

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Po-Sheng Yang Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

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Ming-Nan Chien Division of Endocrinology and Metabolism, Department of Internal Medicine, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

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Shih-Ping Cheng Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan
Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Introduction Papillary thyroid cancer (PTC) is the most common endocrine malignancy, and its incidence is rising worldwide. Although PTC generally follows an indolent course, an increase in the mortality rate for advanced-stage PTC has been

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Andrea Frasoldati Division of Endocrinology, Arcispedale S. Maria Nuova, Reggio Emilia, Italy

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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce, Italy

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Enrico Papini Division of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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subsequent coagulative necrosis and fibrosis, was proven effective for the local control of papillary thyroid microcarcinomas (PTMC) and metastatic lymph nodes in patients at surgical risk [ 8 , 9 ]. Furthermore, a few centres have used TA for palliative

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Luigino Dal Maso Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Daniela Pierannunzio National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy

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Silvia Francisci National Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy

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Angela De Paoli Epidemiological Department, Azienda Zero, Padova, Italy

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Federica Toffolutti Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Salvatore Vaccarella Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France

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Silvia Franceschi Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Ugo Fedeli Epidemiological Department, Azienda Zero, Padova, Italy

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of the DEPTH Working Group
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& Raffaelli M . Papillary thyroid microcarcinoma: extrathyroidal extension, lymph node metastases, and risk factors for recurrence in a high prevalence of goiter area . World Journal of Surgery 2010 34 1214 – 1221 . ( https://doi.org/10.1007/s00268

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Irini S. Hadjisavva Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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Roberto Dina Department of Cellular Pathology, Hammersmith Hospital, Imperial College Healthcare Trust, London, UK

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Michael A. Talias Healthcare Management Postgraduate Program, Open University of Cyprus, Nicosia, Cyprus

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Panayiotis A. Economides Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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: emphasis on correlation with sonographic findings. Yonsei Med J 2011;52:838-844. 10.3349/ymj.2011.52.5.838 21786450 31 Rossing M, Nygaard B, Nielsen FC, Bennedbæk FN: High prevalence of papillary thyroid microcarcinoma in Danish patients: a

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