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Chitra Choudhary Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Leonard Wartofsky Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Eshetu Tefera MedStar Health Research Institute, Washington, D.C., USA

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Kenneth D. Burman Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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can represent benign conditions such as neuromas, postoperative scar, suture granuloma, reactive lymphoid hyperplasia, benign thyroid tissue remnant or, instead, a malignant recurrence of thyroid cancer in which case fine-needle aspiration will show

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000431317
Volume/Issue:
Volume 4: Issue 2
Free access
Hai-Yan Jia Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Juan Chen Department of Ultrasound, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China

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Zi-Xin Zhai Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Wen-Wen Fan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Si-Jie Yuan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Qiong Liu Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Xiao-Hui Yan Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Qian-Qian Shen Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Li-Ping Liu Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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metastasis from ccRCC (HE ×200). D2. Immunohistochemistry shows CD10 (+) (HE ×400). Fine needle aspiration biopsy (FNAB) and core needle biopsy (CNB) were performed on the left lobe nodule. The FNAB results were classified as Bethesda 2. CNB showed

Article Type:
Case Report
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0121
Volume/Issue:
Volume 12: Issue 6
Open access
Catherine Brophy Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Rania Mehanna Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Julie McCarthy Departments of Cytopathology, Cork University Hospital, Cork, Ireland

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Antoinette Tuthill Departments of Endocrinology, Cork University Hospital, Cork, Ireland

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Matthew S. Murphy Departments of Endocrinology, South Infirmary Victoria University Hospital, Cork, Ireland

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Patrick Sheahan Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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clinically apparent thyroid nodules is between 5 and 15% [ 2 ]. Fine-needle aspiration (FNA) cytology has demonstrated high utility in the diagnosis of thyroid nodules. In an effort to stratify thyroid nodules according to risk of malignancy in a consistent

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000441221
Volume/Issue:
Volume 4: Issue 4
Free access
Bülent Öcal Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Mehmet Hakan Korkmaz Department of Otolaryngology, Yıldırım Beyazıt University Medical School, Ankara, Turkey

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Demet Yılmazer Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Tuğba Taşkın Türkmenoğlu Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Ömer Bayır Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Güleser Saylam Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Emel Çadallı Tatar Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Sevilay Karahan Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, Turkey

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Erman Çakal Department of Endocrinology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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methods have been developed, which used a combination of nodule size, age at diagnosis, biochemical variables, fine needle aspiration (FNA) cytology, US features, and molecular analysis [ 3 - 8 ]. The most recent American Thyroid Association

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000494720
Volume/Issue:
Volume 8: Issue 2
Free access
Aly Bernard Khalil Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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Roberto Dina Hammersmith Hospital, London, United Kingdom

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Karim Meeran Hammersmith Hospital, London, United Kingdom

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Ali M. Bakir Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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Saf Naqvi Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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Alia Al Tikritti Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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Nader Lessan Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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Maha T. Barakat Imperial College London Diabetes Center, Abu Dhabi, United Arab Emirates

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]. The ultimate goal of the diagnostic evaluation of a thyroid nodule is to determine whether it is benign or malignant and consequently to provide timely and appropriate treatment. Fine needle aspiration cytology (FNAC) of the thyroid nodule is currently

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000484600
Volume/Issue:
Volume 7: Issue 1
Free access
Irini S. Hadjisavva Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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Roberto Dina Department of Cellular Pathology, Hammersmith Hospital, Imperial College Healthcare Trust, London, UK

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Michael A. Talias Healthcare Management Postgraduate Program, Open University of Cyprus, Nicosia, Cyprus

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Panayiotis A. Economides Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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increased [ 2 ]. Thyroid cancer is present in approximately 5% of nodules, even though rates as high as 15% have been reported [ 1 , 3 , 4 ]. Fine needle aspiration biopsy is the clinical procedure of choice for evaluating whether a nodule is benign or

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000430438
Volume/Issue:
Volume 4: Issue 2
Free access
Signe Buhl Gram Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jacob Høygaard Rasmussen Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jens Bentzen Department of Oncology, Herlev Hospital, Copenhagen University, Copenhagen, Denmark

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Giedrius Lelkaitis Department of Pathology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christian von Buchwald Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christoffer Holst Hahn Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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, however, remains a diagnostic challenge. In Denmark, scintigraphy and ultrasound are performed as part of the investigation in which cold nodules on scintigraphy and suspicious nodules on ultrasound are further investigated with fine-needle aspiration (FNA

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000500539
Volume/Issue:
Volume 8: Issue 5
Free access
Bertrand Volard Departments of Biopathology, Centre François Baclesse, Caen, France

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Sophie Krieger EA 1772, University of Basse-Normandie, Centre François Baclesse, Caen, France
Departments of Biopathology, Centre François Baclesse, Caen, France

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Gaétane Planchard Departments of Biopathology, Centre François Baclesse, Caen, France

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Agnès Hardouin Departments of Biopathology, Centre François Baclesse, Caen, France

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Dominique Vaur Departments of Biopathology, Centre François Baclesse, Caen, France

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Jean-Pierre Rame Departments of Head and Neck Surgery, Centre François Baclesse, Caen, France

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Stéphane Bardet Departments of Nuclear Medicine and Thyroid Unit, Centre François Baclesse, Caen, France

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Introduction Fine needle aspiration (FNA) cytology of thyroid nodules is considered as the key tool to distinguish between benign and malignant tumors [ 1 ]. However, FNA cytology is classified as indeterminate in approximately 20–30% of

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000338922
Volume/Issue:
Volume 1: Issue 2
Free access
Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Andrea Frasoldati Division of Endocrinology, Arcispedale S. Maria Nuova, Reggio Emilia, Italy

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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce, Italy

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Enrico Papini Division of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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disease, is well accepted [ 1 - 3 ]. Fine needle aspiration (FNA) and, to a lesser extent, core needle biopsy (CNB), are currently recognized as the primary diagnostic methods for evaluating thyroid lesions, cervical lymph-node metastases and local

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000506513
Volume/Issue:
Volume 9: Issue 4
Free access
Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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beginning of a vascular encasement. USG-guided fine-needle aspiration cytology (FNAC) was performed on the nodule of greatest size [ 9 ]. FNAC was consistent with ‘suspicious for a follicular neoplasm’ according to the Bethesda system [ 10 ]. Due to the

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000342628
Volume/Issue:
Volume 1: Issue 3
Free access