Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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significantly higher than usually assumed (3% [ 10 ] vs. 18% [ 11 ]). Cerci et al. [ 12 ] found no significant difference in the incidence of thyroid cancer between TMNG and nontoxic multinodular goiter (MNG). The risk of malignancy in Graves' disease might be
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Faculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland
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Faculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland
Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
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Faculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland
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tests and a neck ultrasound, if necessary. Thyroid function tests, such as TSH measurement, are used to assess thyroid function, while ultrasound can help to determine the risk of malignancy of any detected lesions. This diagnostic process is highly
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) conferred a significant and independent predictive risk for thyroid cancer; the association of ATA positivity and risk of malignancy was not affected by gender. This study also demonstrated the importance of increased TSH levels (>1.0 μU/mL) as an
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, Associazione Medici Endocrinologi, and EuropeanThyroid Association Medical Guidelines for Clinical Practice for the Diagnosis and Management of Thyroid Nodules. Endocr Pract 2010; 16(suppl 1): 1–43. 4 Papini E, Guglielmi R, Bianchini A, et al: Risk of
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School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland
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School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland
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School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland
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School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland
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School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland
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categories, and so it is not possible to classify with confidence whether a lesion is benign, suspicious for malignancy, or malignant. The clinical management of these lesions is very difficult due to this undetermined risk of malignancy. The introduction
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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present daVinci robotic system and its restricted instrumentation. As previously suggested, we are of the opinion that the best candidates are slim patients (BMI <22) presenting small unilateral thyroid nodules (<3-4 cm), benign or with a low risk of
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equal trend to increase the risk of malignancy with increasing category, irrespectively of the operator. This is consistent with the results of other previous studies using these systems [ 10 , 11 ]. Also, the percentage of thyroid cancer in different
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. ( https://doi.org/10.1159/000478927 ) 2 Papini E Guglielmi R Bianchini A Crescenzi A Taccogna S Nardi F Panunzi C Rinaldi R Toscano V & Pacella CM . Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound
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; 15 ( 10 ): 1169 – 75 . 10.1089/thy.2005.15.1169 16279851 1050-7256 11 Grani G , Lamartina L , Biffoni M , Giacomelli L , Maranghi M , Falcone R , et al. Sonographically Estimated Risks of Malignancy for Thyroid Nodules
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
Department of Pathology and Oncology, Centro Hospitalar São João, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
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thyroid tumours associated with DICER1; 40% of the cases were syndromic (70/172) and 60% were non-syndromic (102/172) (online suppl. Table 1). In these 172 cases, the risk of malignancy was found to be 67% (47/70) and 75% (77/102) in the syndromic and non