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53 “sometimes” (39%), 41 “frequently” (30.1%), and 34 “always” (25%). Se supplementation was recommended by 83 ETA members (61%) as an alternative to surveillance alone in patients with mild ocular involvement and by 61 (44.9%) as a supplement to the
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postoperative years, only 85/1318 (6%) of the BT-alone patients were being actively followed (remaining at risk), as were 89/541 (16%) of the BT+RRA patients, probably consistent with a greater intensity of postoperative tumor surveillance in those patients who
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Neurofibromatosis Expert Team, Maastricht University Medical Centre, Maastricht, The Netherlands
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Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands
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primary (autoimmune) thyroid disease, and the numbers lost to follow-up make our conclusions not firm but only indicative. Conclusions In the present form our study did not show an increased risk of thyroid pathology in NF1 patients. Active
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TSH. The active surveillance of TSH during pregnancy is justified by the evidence that about 20% of euthyroid women with TAI show TSH values > 4.0 mIU/L throughout gestation [ 27 , 28 ]. Whether or not LT4 treatment (suggested by about 20% of
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thyroid microcarcinoma: time to shift from surgery to active surveillance? Lancet Diabetes Endocrinol . 2016 Nov ; 4 ( 11 ): 933 – 42 . 10.1016/S2213-8587(16)30180-2 27550849 2213-8587 13 Tee YY , Lowe AJ , Brand CA , Judson RT
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low tumour burden, active surveillance was advised. In June 2017, CT and CEA levels were 1097 ng/L and 9.5 µg/L, respectively, and MRI detected new small pelvic bone lesions, so treatment with denosumab was initiated. The symptoms were slowly but
UMR9019, Genome Integrity and Cancers, CNRS, Villejuif, France
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CHU Nantes/ICO, Saint-Herblain, France
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CHU Nantes/ICO, Saint-Herblain, France
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Université de Paris, Paris, France
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Department of Radiology, AP-HP, Hôpital Cochin, Paris, France
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Department of Nuclear Medicine and Endocrine Oncology, Gustave Roussy Institute, Villejuif, France
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Department of Medical Oncology, AP-HP, Hôpital Cochin, Paris, France
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Université de Paris, Paris, France
Department of Endocrinology, AP-HP, Hôpital Cochin, Paris, France
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active surveillance was chosen. Unfortunately, 1 year later, new hepatic and brain metastases (right 25-mm frontal-parietal and left occipital lesions of few millimeters) were diagnosed in the workup of myoclonic seizures of the left hand. This diagnosis
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thyroglobulin to produce thyroid hormone. The active form of thyroid hormone, tri-iodothyronine (T3), is produced by de-iodination of the prohormone T4 by type I and type II iodothyronine de-iodinasesin, a two-substrate ‘ping-pong' mechanism of reaction, along
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responders would never measure TRAb during the pregnancy compared to 11% in women with actively treated GD; p = 0.026 (table 4 ). Table 4 Responders’ recommendations for the measurement of TRAb during pregnancy in a woman with GD on ATDs and in a
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thyroxine (T4). Deiodination of the outer ring generates the active thyroid hormone triiodothyronine (T3), whereas that of the inner ring converts T4 to reverse T3 (rT3), and T3 to 3,3’-diiodo- l -thyronine (T2), which are both biologically inactive