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of the neck with an ice pack may be useful for preventing local bleeding and thermal injury to the skin. After treatment, clinical and US evaluation is needed for detection of potential early adverse effects of the procedure (e.g., hematoma, burns, or
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regulations of the Helsinki Declaration and was approved by the local ethical committee (CEAVNO – Comitato Etico Area Vasta Nord Ovest). Initial treatment Total thyroidectomy was performed in all patients. Since, in our institution, we do not perform
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What Is Known about This Topic? Liposarcomas of the thyroid gland are extremely rare, and there is no definitive consensus within the literature about a comprehensive treatment recommendation yet. What Does This Case Report Add
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approved for the treatment of these patients based on the results of phase III studies (DECISION and SELECT studies) [ 2 , 3 ]. Like many other TKIs, lenvatinib is a multiple kinase inhibitor and inhibits the 3 main vascular endothelial growth factor
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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endocrinologists who are more prone to start L-T3 treatment than GPs. We also demonstrated that the region of residence was related to initiating this treatment. The explanation could be that local doctors’ preferences follow key opinion leaders that are more
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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-R DTC), and it has been recently approved also for the treatment of patients with advanced or unresectable hepatocellular carcinoma (HCC) [ 2 ]. In RAI-R DTC patients on LEN treatment, several adverse events (AEs) have been reported in almost all treated
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surgical complications with the evidence that a second operation rarely results in permanent cure of the neck. Local treatment options are very attractive. Good results have been reported with ethanol injection, but the above-mentioned new techniques seem
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are in the end unhappy with the treatment outcome [ 2 ]. After medical treatment, many patients require some kind of rehabilitative surgery (orbital decompression, squint surgery, eyelid surgery) to correct residual manifestations. The reasons for this
Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden
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Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden
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Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden
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[ 1 , 2 ] and environmental factors [ 3 ]. One strong risk factor is tobacco smoking, which results in higher TRAb at diagnosis of GD and during treatment with thiamazole than in nonsmokers [ 4 ]. It has also been shown that smokers treated with
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Faculty of Medical Sciences of Lisbon, Lisbon, Portugal
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radiation due to local disease persistence (9 patients) and bone (9 patients) or brain metastasis (1 patient); these lesions were not considered for the RECIST assessments. A total of 36 treatment courses were evaluated – 26 with sorafenib and 10 with