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, Ovesen L, Laurberg P, Perrild H, Rasmussen LB, Jørgensen T: Doubling in the use of thyroid hormone replacement therapy in Denmark: association to iodization of salt? Eur J Epidemiol 2011; 26: 629–635. A. Bhaseen: on behalf of the Thyroid
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; Berlin: Roche Elecsys, Basel, Switzerland) and TBG (ARUP Laboratories, Salt Lake City, Utah, USA). Sequencing of the TBG Gene Genomic DNA was isolated from peripheral blood leukocytes after informed consent was obtained. The promoter, the
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seem to be at a relatively high risk of deficiency. This is likely due to the fact that iodine requirements during pregnancy are increased at a time in which iodized salt consumption is decreased [ 3 , 4 , 5 ]. Although the general Greek population is
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the development of multinodular goiter [ 7 ]. After the cessation of salt iodization in Poland in 1980, mild to moderate iodine deficiency was detected. The prevalence of goiter in adults was assessed as 30% [ 8 ]. Consequently, the voluntary model of
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Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
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-monitored salt iodization program in Iran: marked reduction in goiter prevalence and eventual normalization of urinary iodine concentrations without alteration in iodine content of salt . J Endocrinol Invest . 2008 May ; 31 ( 5 ): 422 – 31 . http
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initially perfused with a calcium-free Earle's Balanced Salt Solution (Gibco, Life Technologies, Carlsbad, Calif., USA) containing 50 m M EGTA, and subsequently digested with 0.3 mg/ml type II collagenase (Worthington Biochemical Co., Lakewood N.J., USA) in
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil
Department of Nuclear Medicine, Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil
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Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil
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; consequently, we analyzed 125 patients for determination of the UI after the RID period. The major reason for discontinuation of the diet was difficulty adhering to an RID for a long period of time due to the taste of noniodized salt, as well as difficulty
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. The aminopropionate group is weakly coordinated by two superficial interactions: an H-bond between Asn and the amino group and a salt bridge between the carboxylate and an Arg guanido group. Crystal structures have also been determined for thyroid
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). Iodine in the soil is generally associated with organic matter and is not readily soluble. The magnitude of iodine deposition is unlikely to make a significant contribution to populations in which universal salt iodisation (USI) of 20–40 mg prevails ( 10
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. Guideline: Fortification of Food-grade Salt with Iodine for the Prevention and Control of Iodine Deficiency Disorders . Geneva : WHO 2014 . 5 Zimmermann MB Ito Y Hess SY Fujieda K & Molinari L . High thyroid volume in children with excess