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Wenxing Guo The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Long Tan The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Shuyao Dong The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Ya Jin The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Mei Zhu The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China

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Hongyan Wei The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China

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Yanting Chen The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Lili Fan The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Cong Du The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Wanqi Zhang The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China
The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China
Tianjin Key Laboratory of Environment, Nutrition and Public Health, Tianjin, China
Center for International Collaborative Research on Environment, Nutrition and Public Health, Tianjin, China

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prevalence and thyroid abnormalities on ultrasound analysis [ 2 ]. Goitre is a functional biomarker that can be applied to assessing iodine status in individuals and populations [ 3 ]. The definition of goitre needs reliable volumetric data from local iodine

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Bülent Öcal Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Mehmet Hakan Korkmaz Department of Otolaryngology, Yıldırım Beyazıt University Medical School, Ankara, Turkey

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Demet Yılmazer Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Tuğba Taşkın Türkmenoğlu Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Ömer Bayır Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Güleser Saylam Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Emel Çadallı Tatar Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Sevilay Karahan Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, Turkey

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Erman Çakal Department of Endocrinology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Introduction The estimated prevalence of thyroid nodules in an adult population is 4–7% by palpation and 10–41% by ultrasound (US) scanning [ 1 , 2 ]. The overall malignancy risk, regardless of nodule size, is < 10%, and even smaller nodules

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Francesca Orsolini Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Alessandro Prete Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Pierpaolo Falcetta Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Domenico Canale Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

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Greta Alì Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

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Francesca Manassero Division of Urology, Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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Eleonora Molinaro Department of Clinical and Experimental Medicine, Endocrine Unit, University of Pisa, Pisa, Italy

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, we report the unusual case of a patient with MEN2A syndrome with bilateral testicular metastases from metastatic and advanced MTC, incidentally discovered at ultrasound (US) imaging and histologically confirmed. Case presentation The case was

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M Grussendorf Department of Internal Medicine, University Hospital, Düsseldorf, Germany

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I Ruschenburg MVZ Wagnerstibbe Center for Cytology and Pathology, Einbeck, Germany

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G Brabant Department of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, University of Manchester, Manchester, UK

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Introduction Inclusion of thyroid ultrasound in the routine diagnostic workup greatly increased the number of thyroid nodules detected ( 1 , 2 , 3 , 4 , 5 ). According to epidemiological studies, a prevalence of up to 65% of the adult

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Selwan Khamisi Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

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Peter Lindgren Women's and Children's Health, University Hospital, Uppsala University, Uppsala, Sweden

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F. Anders Karlsson Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

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give a detailed report of a case of dyshormonogenetic fetal goiter and discuss the management and effects of treatment. Case Report A routine ultrasound examination performed at a maternity clinic in the second trimester of pregnancy

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Giovanni Mauri Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, Denmark

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Steven Bandula Interventional Oncology Service, University College Hospital, London, United Kingdom

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Roberto Luigi Cazzato Department of Interventional Radiology, University Hospital of Strasbourg, Strasbourg, France

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Agnieszka Czarniecka The Oncologic and Reconstructive Surgery Clinic, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

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Oliver Dudeck Center for Microtherapy, Klinik Hirslanden, Zurich, Switzerland

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Laura Fugazzola Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Romana Netea-Maier Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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Gilles Russ Thyroid and Endocrine Tumors Unit, La Pitie-Salpetriere Hospital, Sorbonne University, Paris, France

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Göran Wallin Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

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Enrico Papini Department of Endocrinology & Metabolism, Ospedale Regina Apostolorum, Albano, Italy

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the frequently indolent nature of PTMC and the cost and risk of surgery, active surveillance (AS) and ultrasound (US)-guided minimally invasive treatments (MITs) are proposed as alternative management options to thyroidectomy for selected incidental

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Marina Morais Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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João Capela-Costa Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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Luís Matos-Lima Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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José Costa-Maia Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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permanent hoarseness, and, if bilateral, could lead to aphonia or life-threatening dyspnea [ 4 ]. Preoperative ultrasound or computed tomography may provide clues about the existence of an NRLN, thus avoiding iatrogenic injury to the nerve [ 5 ]. This

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Silvia Turcios National Institute of Endocrinology, Cuba

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Juan J. Lence-Anta Institute of Oncology and Radiobiology, Cuba

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Jose-Luis Santana Institute of Oncology and Radiobiology, Cuba

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Celia M. Pereda Institute of Oncology and Radiobiology, Cuba

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Milagros Velasco Institute of Oncology and Radiobiology, Cuba

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Mae Chappe Institute of Oncology and Radiobiology, Cuba

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Idalmis Infante Cuban Health Public Ministry, Havana, Cuba

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Marlene Bustillo Institute of Oncology and Radiobiology, Cuba

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Anabel García Institute of Oncology and Radiobiology, Cuba

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Enora Clero Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Stephane Maillard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Regla Rodriguez Cuban Health Public Ministry, Havana, Cuba

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Constance Xhaard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Yan Ren Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Carole Rubino Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Rosa M. Ortiz Institute of Oncology and Radiobiology, Cuba

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Florent de Vathaire Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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with thyroid cancer risk in a case-control study [ 12 ]. Thyroid volume was measured by ultrasound in half of the controls of the case-control study in order to understand the relationship between the determinants of thyroid volume and those of the

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Taha Yusuf Kuzan Department of Radiology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey

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Ceren Canbey Goret Department of Surgical Pathology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey

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Introduction Nodule development is a commonly seen entity in the thyroid gland, and 4–7% of the adult population has a palpable thyroid nodule [ 1 ]. With imaging modalities, especially the widespread use of ultrasound

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Marek Niedziela Department of Pediatric Endocrinology and Rheumatology, Poznan University of Medical Sciences, Poznan, Poland

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Nelly Sabbaghian Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada

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Leanne de Kock Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada

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William D. Foulkes Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada

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and follow-up of ectopic intrathyroidal thymic tissue can be performed noninvasively by thyroid ultrasound. Ectopic juvenile intrathyroidal thymus presents as a solid and hypoechogenic area, with regular and sharp margins and no blood flow on power

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