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Patrick W. Owens Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Terri P. McVeigh Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
Cancer Genetics Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom

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Eoin J. Fahey Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Marcia Bell Department of Endocrinology, Galway University Hospital, Galway, Ireland

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Denis S. Quill Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Michael J. Kerin Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Aoife J. Lowery Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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impairment, or sialadenitis. More significant complications include impairment of haematopoiesis and gonadal function and increased risk for second primary malignancies, both solid and haematological. A dose of 100 mCi (3.7 GBq) of radioiodine has been

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000493261
Volume/Issue:
Volume 7: Issue 6
Free access
Pi-Ling Chiang Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Sheng-Dean Luo Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yen-Hsiang Chang Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Chen-Kai Chou Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Shun-Yu Chi Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yi-Fan Chen Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Wei-Che Lin Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan

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/FLUS) category, known as Bethesda category III, has been ascribed a malignancy risk of 5–15% ( 2 , 3 , 4 , 5 ). According to international guidelines, Bethesda III thyroid nodules are not considered an indication of radiofrequency ablation (RFA) ( 6 , 7

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0105
Volume/Issue:
Volume 12: Issue 6
Open access
Rima Bėrontienė Clinics of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Edita Jašinskienė Clinics of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Rosita Kiudelienė Clinics of Pediatrics, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Gintaras Kuprionis Clinics of Radiology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Jurgita Makštienė Clinics of Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Raminta Macaitytė Clinics of Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Dalia Marčiulionytė Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Lina Poškienė Clinics of Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Agnė Šemetaitė Clinics of Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Vygantas Šidlauskas Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Raimondas Valickas Clinics of Radiology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Rimantas Žalinkevičius Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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Rasa Verkauskienė Clinics of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania
Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania

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deficiency [ 9 ]. Both of these risk factors were present in Lithuania at certain time periods, i.e. the radioactive cloud after the Chernobyl accident passed over the territory, and Lithuania was considered to be a mild to moderate iodine-deficient zone up

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000450921
Volume/Issue:
Volume 6: Issue 1
Free access
Kristine Z Swan Department of ORL, Head- and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark

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Johnson Thomas Department of Endocrinology, Mercy Hospital, Springfield, Missouri, USA

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Viveque E Nielsen Department of ORL, Head- and Neck Surgery, Odense University Hospital, Odense, Denmark

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Marie Louise Jespersen Department of Pathology, Aarhus University Hospital, Aarhus, Denmark

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Steen J Bonnema Department of Endocrinology, Odense University Hospital, Odense, Denmark

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stratification of thyroid nodules, of which only few are malignant ( 3 ). Therefore, clinicians must balance the risk of overlooking malignancy while reducing the number of unnecessary biopsies in order to avoid overtreatment of benign nodules. If a biopsy is

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-21-0129
Volume/Issue:
Volume 11: Issue 2
Open access
Axel Sahovaler Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada
Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada

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Marco Ferrari Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada
Unit of Otorhinolaryngology – Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy
Section of Otorhinolaryngology – Head and Neck Surgery, Department of Neurosciences, University of Padua, Padua, Italy

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Jonathan Athayde Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Adrian Mendez Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Kevin Fung Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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John Yoo Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Anthony C. Nichols Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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S. Danielle MacNeil Department of Otolaryngology-Head and Neck Surgery, Western University, London, Ontario, Canada

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Dear Editor, The recently published “Systematic Review of Recurrence Rate after Hemithyroidectomy for Low-Risk Well-Differentiated Thyroid Cancer” (WDTC) by Chan et al. [ 1 ] aimed to focus on tumors between 1 and 4 cm, which represent the

Article Type:
Letter
DOI:
https://doi.org/10.1159/000511870
Volume/Issue:
Volume 10: Issue 2
Free access
Pedro Weslley Souza Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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. References 1 Russ G, Bonnema SJ, Erdogan MF, Durante C, Ngu R, Leenhardt L: European Thyroid Association guidelines for ultrasound malignancy risk stratification of thyroid nodules in adults: The EU-TIRADS. Eur Thyroid J 2017; 6: 225–237. 10

Article Type:
Letter
DOI:
https://doi.org/10.1159/000486671
Volume/Issue:
Volume 7: Issue 3
Free access
Johannes Järhult Department of Surgery, Highland Hospital, Eksjö, Sweden
Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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Ramtin Vedad Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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, Sugawara M: Fate of untreated benign thyroid nodules: results of long-term follow-up. World J Surg 1994;18:495-499. 10.1007/BF00353745 7725734 20 Rios A, Rodriguez JM, Canteras M, Galindo PJ, Balsalobre MD, Parrilla P: Risk factors for malignancy in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367845
Volume/Issue:
Volume 3: Issue 4
Free access
Mathieu Spaas Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Brigitte Decallonne Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Annouschka Laenen Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium

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Jaak Billen Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

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Sandra Nuyts Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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account biochemical disease recurrence or persistence without structural evidence of malignancy. As research into improving prognostication in DTC patients continues, the ATA has recently introduced the concept of dynamic risk stratification. Furthermore

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000489849
Volume/Issue:
Volume 7: Issue 4
Free access
Rachelle P Mendoza Department of Pathology, University of Rochester Medical Center, Rochester, New York, USA

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Richard Cody Simon Department of Pathology, University of Chicago, Chicago, Illinois, USA

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Nicole A Cipriani Department of Pathology, University of Chicago, Chicago, Illinois, USA

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Tatjana Antic Department of Pathology, University of Chicago, Chicago, Illinois, USA

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, along with recommended follow-up management based on risk of malignancy ( 1 ). A large majority (65–75%) of thyroid nodules are benign ( 2 ); however, several studies have confirmed a minor yet nonnegligible 1–10% risk of a false-negative cytologic

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0153
Volume/Issue:
Volume 13: Issue 1
Open access
Alexander Gorshtein Endocrine Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Ilana Slutzky-Shraga Endocrine Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Eyal Robenshtok Endocrine Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Carlos Benbassat Endocrine Institute, Shamir Medical Center (Formerly Assaf Harofeh Medical Center), Beer Yaakov, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Dania Hirsch Endocrine Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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. Nodules are divided into 6 diagnostic categories with different implied risk of malignancy (ROM) and clinical management guidelines [ 1 ]. According to the original classification, Bethesda III (B3) nodules have a relatively low (5–15%) ROM and might be

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000509037
Volume/Issue:
Volume 10: Issue 2
Free access