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difference in treatment was made based on size. Furthermore, empirical RAI therapy was initially given to all patients with elevated Tg levels, even when no iodine avid disease was seen on the pretherapy scan. Our center did not have a PET/CT scanner before
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urinary iodine (100–149 ug/L) had median serum TSH and FT4 levels comparable with those in the reference group (urinary iodine between 150 and 249 µg/L) [ 21 ]. Also, in a study performed in Belgium (an area with a moderate ID), serum TSH concentrations
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case in pregnancy ( 29 ). Another study from Amsterdam in pregnant women in an iodine replete area showed that with increasing term, plasma FT4 and FT3 concentrations decreased with a concomitant increase of free rT3 levels, changes that are also found
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from the Wolff-Chaikoff effect [ 10 ], resulting in a normalization of T 4 and TSH serum concentrations. In this phase, serum total T 4 (TT 4 ), free T 4 (FT 4 ), and reverse T 3 (rT 3 ) levels increase, while serum total T 3 (TT 3 ) and free T 3
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National Maternity Hospital, Dublin, Ireland
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iodine intake to ensure sufficient iodide for normal fetal development. Previous studies by our group have shown similar levels of iodide uptake in placenta to that of thyroid and have identified a previously unreported capacity of the placenta to store
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thyroid gland remain poorly characterized. It is generally accepted that ICM can cause thyroid dysfunction (TD) because of supraphysiological concentrations of iodine in the contrast solution [ 2 - 5 ]. While the normal thyroid gland can usually adapt to
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serum selenium concentration was 81.8 ± 14.6 μg/l (median = 83; range = 32-112) and was consistent with the values reported in Europeans [ 23 ]. Thyroid echogenicity, measured as mean gray-scale pixel value (89.8 ± 16.9), was consistent with the levels
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Department of Endocrinology, Metabolism and Diabetes, Evgenideion Hospital, Athens University School of Medicine, Athens, Greece
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hypothyroidism; metformin treatment led to a significant reduction of TSH levels that was reversed when metformin was discontinued, whereas TH levels were unaltered. Interestingly, the degree of TSH reduction was associated with baseline TSH concentration. Since
Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Badalona, Spain
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Department of Obstetrics & Gynecology, Germans Trias i Pujol University Hospital, Badalona, Spain
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Health Department, Centre d’Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Generalitat de Catalunya, Badalona, Spain
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Health Department, Centre d’Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Generalitat de Catalunya, Badalona, Spain
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Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain
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Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain
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Health Department, Centre d’Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Generalitat de Catalunya, Badalona, Spain
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Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Badalona, Spain
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intra-analysis CVs were <5.9%. The reference range for the general population is <4.11 IU/mL. Urine fluid iodine concentrations were measured following the Benotti technique ( 10 ). Statistical analyses Multiple imputation algorithms were used to
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) in the presence or absence of stimulation of thyroidal iodide uptake by treatment with a low-iodine diet (LID) for 1-4 weeks or exogenous thyroid-stimulating hormone (TSH) application prior to the administration of radioiodide [ 3 , 4 , 5 , 6 , 7 , 8