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Hirosuke Danno Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Eijun Nishihara Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Kazuyoshi Kousaka Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Tomohiko Nakamura Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Toshihiko Kasahara Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Takumi Kudo Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Mitsuru Ito Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Shuji Fukata Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Mitsushige Nishikawa Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Akira Miyauchi Division of Surgery and Director, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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tissue. AFTNs are common in iodine-deficient areas, accounting for up to 60% of cases of thyrotoxicosis. However, it is rare (3–10% of cases of thyrotoxicosis) in regions with sufficient iodine supply [ 5 ]. The prevalence of AFTNs in iodine

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000510312
Volume/Issue:
Volume 10: Issue 6
Open access
Theodora Pappa Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital

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Maria Alevizaki Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital
Department of Endocrinology, Metabolism and Diabetes, Evgenideion Hospital, Athens University School of Medicine, Athens, Greece

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+ /I - symporter activity and iodine uptake by the thyroid gland and that TSH suppresses AMPK phosphorylation and activation [ 37 ]. This was also confirmed by other researchers and this process appears to be regulated at the transcriptional level [ 38

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000346248
Volume/Issue:
Volume 2: Issue 1
Free access
Laure Felix Univ. Grenoble Alpes, Department of Radiology, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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Peggy Jacon Univ. Grenoble Alpes, Department of Cardiology, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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Maxime Lugosi Univ. Grenoble Alpes, Department of Internal Medicine, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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Justine Cristante Univ. Grenoble Alpes, Department of Endocrinology, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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Julie Roux Univ. Grenoble Alpes, Department of Nuclear Medicine, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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Olivier Chabre Univ. Grenoble Alpes, Department of Endocrinology, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France

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tomography (FDG-PET) with integrated unenhanced CT scan. Although there was no thyroid signal on FDG PET, we noticed that in the unenhanced CT scan the thyroid had become 'white', suggesting that intrathyroid accumulation of iodine brought by amiodarone acted

Article Type:
Case Report
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-21-0047
Volume/Issue:
Volume 11: Issue 1
Open access
Katarzyna Pelewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Rafał Wolny Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland

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Tomasz Bednarczuk Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Piotr Miśkiewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Introduction The proper synthesis of thyroid hormones is dependent on adequate iodine supply. The mean daily iodine intake recommended by the World Health Organization is 150 μg [ 1 ]. Iodinated contrast media (ICM) typically contain 13,500 μg

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000515126
Volume/Issue:
Volume 10: Issue 4
Free access
Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce, Italy

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia”, Udine, Italy

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Vincenzo Toscano Endocrinology, Department of Clinical and Molecular Medicine, Sant’Andrea Hospital, Sapienza University of Rome, Roma, Italy

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Dan Alexandru  Niculescu Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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Diana Loreta  Paun Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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Catalina Poiana Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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test is left to individual initiative ( p < 0.01). More than 80% reported that the number of endocrine referrals for thyroid disease in pregnancy is increased (slightly or considerably) compared to the past ( p < 0.01). Iodine supplementation should

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000490944
Volume/Issue:
Volume 7: Issue 6
Free access
Kathrin A. Schmohl Department of Internal Medicine II, Germany

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Andrea M. Müller Department of Internal Medicine II, Germany

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Nathalie Schwenk Department of Internal Medicine II, Germany

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Kerstin Knoop Department of Internal Medicine II, Germany

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Eddy Rijntjes Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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Josef Köhrle Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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Heike Heuer Leibniz Institute for Environmental Medicine, Düsseldorf, Germany

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Peter Bartenstein Department of Nuclear Medicine, Germany

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Burkhard Göke Department of Internal Medicine II, Germany

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Peter J. Nelson Medical Policlinic IV, University Hospital of Munich, Munich, Germany

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Christine Spitzweg Department of Internal Medicine II, Germany

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) in the presence or absence of stimulation of thyroidal iodide uptake by treatment with a low-iodine diet (LID) for 1-4 weeks or exogenous thyroid-stimulating hormone (TSH) application prior to the administration of radioiodide [ 3 , 4 , 5 , 6 , 7 , 8

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000381019
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Barbara A. Demeneix CNRS/UMR7221, Muséum National d’Histoire Naturelle/Université Paris-Sorbonne, Paris, France

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, observational studies demonstrate that in humans even mild maternal iodine deficiency can be associated with impaired child brain development and IQ loss [ 4 ]. Iodine is a major component of THs and pivotal for TH synthesis. In line with this, iodine

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000504668
Volume/Issue:
Volume 8: Issue 6
Free access
Sze May Ng Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
Department of Paediatrics, Southport and Ormskirk NHS Trust, Ormskirk, United Kingdom

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Mark A. Turner Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

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Shivaram Avula Department of Radiology, Alder Hey Foundation Trust Hospital, Liverpool, United Kingdom

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pregnancy the maternal iodine supply may influence complex changes of maternal thyroid function, which may affect the neonatal thyroid gland [ 22 ]. In 1992, most European countries (with the exceptions of Switzerland, Austria, Great Britain, and most

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000481857
Volume/Issue:
Volume 7: Issue 1
Free access
Furio Pacini Section of Endocrinology, University of Siena, Siena, Italy

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Dagmar Fuhrer Department of Endocrinology, Diabetes and Metabolism, West German Cancer Centre (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany

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Rossella Elisei Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Daria Handkiewicz-Junak Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

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Sophie Leboulleux Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Markus Luster Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany

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Martin Schlumberger Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Johannes W Smit Radboud University Medical Center, Nijmegen, Netherlands

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iodine (RAI) therapy can be administered to patients with DTC for various indications. The non-descript colloquial use of the word 'ablation' has thus far frustrated a constructive scientific dialogue. While it has generally been recognized that the

Article Type:
Other
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-21-0046
Volume/Issue:
Volume 11: Issue 1
Open access
Marta Kostecka-Matyja Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Anna Fedorowicz Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Ewa Bar-Andziak Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Tomasz Bednarczuk Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Monika Buziak-Bereza Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Paulina Dumnicka Department of Medical Diagnostics, Jagiellonian University, Collegium Medicum, Krakow

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Maria Górska Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Małgorzata Krasnodębska Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Beata Niedźwiedzka Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Dorota Pach Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Bogdan Solnica Department of Diagnostics, Chair of Clinical Biochemistry, Jagiellonian University, Collegium Medicum, Krakow, Poland

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Jerzy Sowiński Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Małgorzata Szelachowska Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Małgorzata Trofimiuk-Müldner Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Katarzyna Wachowiak-Ochmańska Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Alicja Hubalewska-Dydejczyk Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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concentration of estrogens, and a relative iodine deficiency [ 10 ]. Accordingly, it can be expected that thyrotropin (TSH) and free thyroid hormones concentrations in normal pregnancy differ from those in the general population. Moreover, dynamic changes occur

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000453061
Volume/Issue:
Volume 6: Issue 2
Free access