Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
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Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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Amsterdam Public Health Research Institute, Amsterdam UMC, The Netherlands
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Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
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Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
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Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location Vrije Universiteit Amsterdam, Boelelaan, Amsterdam, The Netherlands
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Laboratory Specialized Diagnostics & Research, Department of Laboratory Medicine, Amsterdam UMC, University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Public Health Research Institute, Meibergdreef, Amsterdam, The Netherlands
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conducted a systematic search in PubMed and Embase. In addition, we searched the following websites and guideline-specific databases: Guidelines International Network (G-I-N; http://g-i-n.net ), Trip database ( http://www.tripdatabase.com ), and Clinical
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Availability fT4 and fT3 enter peripheral target cells via specific cell membrane transporter proteins with differing patterns of tissue distribution. Several thyroid hormone transporters have been identified, including the monocarboxylate transporters 8 and
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cognate receptor TSHR at the basolateral membrane, iodide is uptaken through the sodium/iodide symporter (NIS) and the expression of several thyroid-specific genes is activated, including Tg. Iodide is likely transported from the cytosol to the lumen by
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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evaluation of maternal thyroid function in early pregnancy is challenged by the physiological alterations in thyroid function and binding proteins associated with the pregnant state ( 7 ). Thus, pregnancy- and method-specific reference ranges are needed for
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= 0.57). Cutoff Value of FNA-Tg Using a ROC curve to analyze the best cutoff point for FNA-Tg, the value 4.41 ng/mL obtained a sensitivity of 98% and specificity of 96%, area under the curve 0,984 (95% CI 0,958–1,0; Fig. 2 ). In all patients
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Departments of Scuola Superiore Sant'Anna, Pisa, Italy
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complex, its final yield is uncertain, and cross-reactivity might occur. Mass spectrometry (MS) coupled to high-performance liquid chromatography (HPLC) has been proposed as a highly specific and sensitive technique to assay TH. MS-based techniques have
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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shows considerable dynamics within the first trimester of a pregnancy which necessitates the use of pregnancy-specific reference intervals in the assessment of maternal thyroid function ( 3 ). In the kidney, an increase in renal plasma flow and the
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan
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Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan
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SUVs on a large scale for normal thyroid function and to examine the utility of SUVs in detecting thyroid function. Semantic segmentation assigns each pixel in images to a specific class and can provide a map of specific structures, such as organs and
Department of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan
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improve overall and disease-specific survival, reduce the risk of persistent/recurrent disease and associated morbidity, and permit accurate disease staging and risk stratification while minimizing treatment-related morbidity and unnecessary therapy ( 4
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are shown as means ± SD. Horizontal lines indicate the maximum value of the reference interval for the specific TH (minimum value for TSH, respectively). Proteomic Profiling of Plasma Proteins Mass spectrometric analysis of all 80