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Hao Li Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otorhinolaryngology, Tan Tock Seng Hospital, Singapore, Singapore

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Nir Livneh Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Ramat Gan, Israel

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Snjezana Dogan Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Ashok R. Shaha Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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of both tumors in the same thyroid gland is observed in 14.7% of thyroidectomies performed for medullary thyroid carcinomas in a series of 82 cases [ 3 ]. However, collision metastases of these 2 tumors in the same cervical lymph node have only been

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Maria Mavromati Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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Essia Saiji Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Marco Stefano Demarchi Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Vincent Lenoir Department of Radiology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Amanda Seipel Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Paulina Kuczma Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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François R Jornayvaz Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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Minerva Becker Department of Radiology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Eugenio Fernandez Department of Oncology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Claudio De Vito Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Frédéric Triponez Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Sophie Leboulleux Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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surgical procedure performed in most cases and depending on the final pathology and risk of recurrence classification, a second surgery may be necessary to complete total thyroidectomy. Preoperative molecular analyses are now available for suspicious

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Johannes Järhult Department of Surgery, Highland Hospital, Eksjö, Sweden
Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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Ramtin Vedad Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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in continued expectancy. Thus, 22% of the original 473 patients underwent thyroid surgery during the follow-up period. The predominant operations were lobectomy (53) and total thyroidectomy (41). Table 1 Main indication for 236 re

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Samuel Chan Department of Ear, Nose, and Throat Surgery, St George’s Hospital, London, United Kingdom

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Katarina Karamali Department of Ear, Nose, and Throat Surgery, St George’s Hospital, London, United Kingdom

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Anna Kolodziejczyk Department of Ear, Nose, and Throat Surgery, St George’s Hospital, London, United Kingdom

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Georgios Oikonomou Department of Ear, Nose, and Throat Surgery, St George’s Hospital, London, United Kingdom

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John Watkinson Department of Ear, Nose, and Throat Surgery, GOSH, London, United Kingdom

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Vinidh Paleri The Royal Marsden Hospital, London, United Kingdom

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Iain Nixon Department of Ear, Nose, and Throat Surgery, NHS Lothian, University of Edinburgh, Edinburgh, United Kingdom

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Dae Kim Department of Ear, Nose, and Throat Surgery, St George’s Hospital, London, United Kingdom

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to increased use of imaging. Adequate surgery remains the most important prognostic determinant in the management of DTC [ 2 ]. The standard of care until recently has been total thyroidectomy (TT) and adjuvant radio-active iodine (RAI) for all such

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Kirsten E. Stewart Department of Head and Neck Surgery, St John’s Hospital at Howden, Livingston, United Kingdom

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Mark W.J. Strachan Metabolic Unit, Western General Hospital, Edinburgh, United Kingdom

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Devraj Srinivasan Department of Oncology, Western General Hospital, Edinburgh, United Kingdom

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Morna MacNeill Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

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Lucy Wall Department of Oncology, Western General Hospital, Edinburgh, United Kingdom

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Iain J. Nixon Department of Head and Neck Surgery, St John’s Hospital at Howden, Livingston, United Kingdom

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cancer (PTC) treated with TKI therapy and who subsequently underwent total thyroidectomy and central lymph node dissection. Very few patients treated with TKIs for unresectable local disease have been reported to date; hence, the clinical and pathological

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Matthieu Bosset Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Maxime Bonjour Service de Biostatistique, Hospices Civils de Lyon, Lyon, France

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Solène Castellnou Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Zakia Hafdi-Nejjari Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Claire Bournaud-Salinas Centre de Médecine Nucléaire, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Myriam Decaussin-Petrucci Service d’Anatomie-Pathologique, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France

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Jean Christophe Lifante Service de Chirurgie Endocrinienne, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France
Laboratoire Health Services and Performance Research (EA 7425 HESPER), Université Claude Bernard Lyon 1, Villeurbanne, France

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Agnès Perrin Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Jean-Louis Peix Service de Chirurgie Endocrinienne, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France

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Philippe Moulin Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
CarMeN Laboratory, Université Claude-Bernard Lyon 1, Inserm U1060, INRA U1397, INSA Lyon, IMBL, Villeurbanne, France

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Geneviève Sassolas Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Michel Pugeat Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Françoise Borson-Chazot Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
Laboratoire Health Services and Performance Research (EA 7425 HESPER), Université Claude Bernard Lyon 1, Villeurbanne, France

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mainstay of PTC treatment is surgical resection which allows removal of the tumor, perform histology, and classify patients (4–5). Lobectomy was performed in our center mostly during the eighties and early nineties. Total thyroidectomy, which has been

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Anne-Sophie Bertrand Department of Interventional Radiology Imaging, Antoine Lacassagne Cancer Research Center, Nice, France

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Antoine Iannessi Department of Interventional Radiology Imaging, Antoine Lacassagne Cancer Research Center, Nice, France

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Isabelle Peyrottes Department of Anatomopathology, Antoine Lacassagne Cancer Research Center, Nice, France

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Alexis Lacout Department of Radiology, Centre médico-chirurgical ELSAN, Aurillac, France

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Antoine Thyss Department of Oncology, Antoine Lacassagne Cancer Research Center, Nice, France

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Pierre-Yves Marcy Department of Interventional Radiology and Diagnostic Imaging, Polyclinique Les Fleurs Groupe ELSAN, Ollioules, France

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thyroidectomy and central lymph node dissection in March 2012. The size of the papillary thyroid tumor was 12 mm. PTC was of pure common papillary histological pattern (Fig.  1 ). Neither thyroid capsule invasion nor extrathyroid extension had been found on a

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Mathieu Spaas Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Brigitte Decallonne Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Annouschka Laenen Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium

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Jaak Billen Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

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Sandra Nuyts Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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of DTC usually consists of total thyroidectomy followed by radioactive iodine (RAI) remnant ablation (RRA). Postoperative administration of RAI serves three major goals: the first is to destroy any residual microscopic disease as well as any remaining

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Clotilde Saïe Thyroid and Endocrine Tumors Unit, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Cécile Ghander Thyroid and Endocrine Tumors Unit, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Samir Saheb Apheresis Unit, Pitié-Salpêtrière Hospital, AP-HP, Sorbonne University, Paris, France

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Christel Jublanc Department of Endocrinology, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Denis Lemesle Department of Anaesthesia, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Charlotte Lussey-Lepoutre Nuclear Medicine Department, Pitié-Salpêtrière Hospital APHP, Sorbonne Université, Inserm U970, Paris, France

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Laurence Leenhardt Thyroid and Endocrine Tumors Unit, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Fabrice Menegaux Department of Surgery, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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Christophe Tresallet Department of Surgery, Avicennes Hospital, Paris, France

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Camille Buffet Thyroid and Endocrine Tumors Unit, Pitié-Salpêtrière Hospital APHP, Sorbonne University, Paris, France

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any radical treatment of hyperthyroidism (i.e., thyroidectomy or radioiodine treatment) [ 1 ]. We report a retrospective series of 22 hyperthyroid patients who underwent TPE in our tertiary care center hospital. Our goals were to describe the use

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Pedro Weslley Souza Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Gabriela Franco Mourão Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Pedro Henrique Lopes Oliveira Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Tulio Henrique Silva Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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them with some metastases > 5 mm. None of the patients had serum thyroglobulin > 2 ng/mL after total thyroidectomy or > 10 ng/mL after lobectomy with isthmectomy, or a clinical suspicion of metastases in the first assessment and 18 months after surgery

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