Search for other papers by Mario Rotondi in
Google Scholar
PubMed
Search for other papers by Maria Grazia Castagna in
Google Scholar
PubMed
Search for other papers by Carlo Cappelli in
Google Scholar
PubMed
Search for other papers by Cristina Ciuoli in
Google Scholar
PubMed
Search for other papers by Francesca Coperchini in
Google Scholar
PubMed
Search for other papers by Francesco Chiofalo in
Google Scholar
PubMed
Search for other papers by Fabio Maino in
Google Scholar
PubMed
Search for other papers by Paola Palmitesta in
Google Scholar
PubMed
Search for other papers by Luca Chiovato in
Google Scholar
PubMed
Search for other papers by Furio Pacini in
Google Scholar
PubMed
Introduction An increased incidence of thyroid cancer has been reported in many countries, including the USA and some countries in Europe [ 1 ]. This trend may be partially attributable to medical surveillance or environmental factors and
Search for other papers by Thomas Szabo Yamashita in
Google Scholar
PubMed
Search for other papers by Fady J. Baky in
Google Scholar
PubMed
Search for other papers by Travis J. McKenzie in
Google Scholar
PubMed
Search for other papers by Geoffrey B. Thompson in
Google Scholar
PubMed
Search for other papers by David R. Farley in
Google Scholar
PubMed
Search for other papers by Melanie L. Lyden in
Google Scholar
PubMed
Search for other papers by Benzon M. Dy in
Google Scholar
PubMed
, it remains rare with an estimated incidence of 1 in 200,000–250,000 [ 1 , 2 ]. As such, providers can be unfamiliar with these patients and the surgical management of the disease. Features of Cowden syndrome are benign and malignant mucocutaneous
Search for other papers by Shigenobu Nagataki in
Google Scholar
PubMed
expected prevalence calculated as a cumulative incidence via a life-table method using thyroid cancer incidence rates from 2001-2010 was 5.2, giving an observed/expected ratio of 30.8 [ 7 ]. Interim Reports from Prefectural and National Committees in
Search for other papers by Sébastien Verdickt in
Google Scholar
PubMed
Search for other papers by Falco Van Nes in
Google Scholar
PubMed
Search for other papers by Carolien Moyson in
Google Scholar
PubMed
Search for other papers by Toon Maes in
Google Scholar
PubMed
Search for other papers by Paul Van Crombrugge in
Google Scholar
PubMed
Search for other papers by Annick Van den Bruel in
Google Scholar
PubMed
Search for other papers by Brigitte Decallonne in
Google Scholar
PubMed
not been well studied as a predictive factor for thyroid functional outcome. In this study, we hypothesize that a positive TPO Ab status prior to the first administration of RAI in patients with Graves’ disease increases the incidence of post RAI
Search for other papers by Irini S. Hadjisavva in
Google Scholar
PubMed
Search for other papers by Roberto Dina in
Google Scholar
PubMed
Search for other papers by Michael A. Talias in
Google Scholar
PubMed
Search for other papers by Panayiotis A. Economides in
Google Scholar
PubMed
Introduction Thyroid nodules are extremely common with a prevalence of about 20-76% of the adult population based on detection by ultrasonography [ 1 ]. Thyroid cancer is rare; however, in the past few decades its incidence has significantly
Search for other papers by Peter Laurberg in
Google Scholar
PubMed
are associated with much variation in incidence of Graves' disease, but they affect inflammatory bowel disease much less [ 14 ]. Accordingly, the way forward is to organize prospective controlled studies of new immune modulating drugs in GO, and not
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
Search for other papers by Mafalda Marcelino in
Google Scholar
PubMed
Search for other papers by Pedro Marques in
Google Scholar
PubMed
Search for other papers by Luis Lopes in
Google Scholar
PubMed
Search for other papers by Valeriano Leite in
Google Scholar
PubMed
Search for other papers by João Jácome de Castro in
Google Scholar
PubMed
seen as a protective condition for thyroid cancer, and a relationship between low serum TSH levels and a lower incidence of papillary carcinoma has been suggested [ 6 , 7 ]. However, a recent meta-analysis could not confirm this association [ 8
Search for other papers by Haggi Mazeh in
Google Scholar
PubMed
Search for other papers by Amir Orlev in
Google Scholar
PubMed
Search for other papers by Ido Mizrahi in
Google Scholar
PubMed
Search for other papers by David J. Gross in
Google Scholar
PubMed
Search for other papers by Herbert R. Freund in
Google Scholar
PubMed
signal transduction), and a translocation in PPARγ1 (tumor suppressor gene). However, the incidence of these mutations has been estimated to be lower than both PTC and MTC [ 8 ]. To date, there is no known common mutation involved in the pathogenesis
Department of Clinical Sciences, Lund University, Lund, Sweden
Search for other papers by Bengt Hallengren in
Google Scholar
PubMed
Department of Clinical Sciences, Lund University, Lund, Sweden
Search for other papers by Tereza Planck in
Google Scholar
PubMed
Department of Clinical Sciences, Lund University, Lund, Sweden
Search for other papers by Peter Åsman in
Google Scholar
PubMed
Department of Clinical Sciences, Lund University, Lund, Sweden
Search for other papers by Mikael Lantz in
Google Scholar
PubMed
rather uncommon inflammatory disorder of the thyroid and only a few incidence studies are available. Of 160 patients studied in the period 1960-1997 at the Mayo Clinic, an age- and sex-adjusted incidence of 4.9 cases of SAT/100,000/year was noted [ 1
Search for other papers by Juan Bernal in
Google Scholar
PubMed
Search for other papers by Maria Jesús Obregon in
Google Scholar
PubMed
Search for other papers by Pilar S. Santisteban in
Google Scholar
PubMed
incidence of goiter in the Alpujarras, a mountainous region near Granada. This was the start of a brilliant and influential scientific career together with her husband Prof. Francisco Escobar del Rey, who died in December 2015. They spent a postdoctoral stay
