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Recommendations for Pregnant Patients or Patients Planning Pregnancy? The maternal gestational thyroid function has a crucial impact on pregnancy, fetal, and neonatal outcomes; therefore, TD occurring during pregnancy, especially if overt, require a prompt
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, measurement of serum TSH (and if low, T4 and T3) 3–4 weeks after ICM exposure is advised. Routine screening for ICM-induced Hypo may be also considered in selected high-risk patients, especially in women planning pregnancy after hysterosalpingography with oil
In the article “Side Effects of Anti-Thyroid Drugs and Their Impact on the Choice of Treatment for Thyrotoxicosis in Pregnancy” by Taylor and Vaidya [Eur Thyroid J 2012;1:176–185], the sentence in the right column on line 1, p. 179
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Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
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iodine ( n = 2), pregnancy ( n = 145), TSH <0.1 and TSH >10 µ/L ( n = 279) as well as those with incomplete laboratory or missing data ( n = 211). Subsequently, 4,905 eligible participants remained to enter the current study (Fig. 1 ) . Fig. 1
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, particularly during uterine life. Therefore, in the WT progeny of affected mothers, the upregulation of DIO3 during pregnancy seems to be a physiologic adaptation to the high maternal levels of TH. However, the persistence of reduced sensitivity to TH in WT
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LA , Zarek SM , Perkins NJ , Silver R , et al. Subclinical Hypothyroidism and Thyroid Autoimmunity Are Not Associated With Fecundity, Pregnancy Loss, or Live Birth . J Clin Endocrinol Metab . 2016 Jun ; 101 ( 6 ): 2358 – 65 . 10
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gestation. In contrast, TSH receptor antibodies have a prevalence of around 0.01%, but neonatal hyperthyroidism occurs in 30% of TSH receptor antibody-positive women [ 2 ]. Course of Graves’ Disease during Pregnancy Deterioration in the clinical
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We thank Dr. Negro for his letter on our study and would like to comment on the five points he makes. (1) If maternal TSH and FT4 levels were unrelated to childhood IQ in our population, the conclusion against screening in pregnancy would
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Institut National de la Recherche Médicale, UMR U895, University Nice-Sophia-Antipolis, Nice, France
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women planning a pregnancy. Our study targeted normal women seen in early pregnancy in a clinical setting, thus we had no access to women before pregnancy. A prospective randomized interventional study on supplementation before pregnancy was not feasible
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Introduction Adequate dietary iodine consumption, as determined by the urinary iodine concentration (UIC), is necessary for a normal thyroid function. During pregnancy, iodine requirements are increased [ 1 ] as a result of both the normal