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Dagmar Führer Department of Endocrinology and Metabolism, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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Klaudia Brix Department of Life Sciences and Chemistry, Jacobs University Bremen, Bremen, Germany

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Heike Biebermann Institut für Experimentelle Pädiatrische Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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below reference ranges were found in 3.5% (SHIP) to 1.7% (KORA) of the study populations [ 16 ]. Overall, the prevalence of TSH concentrations outside the assay reference ranges was higher in women than men, and this has been observed in most

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000431318
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Katarzyna Pelewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Rafał Wolny Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland

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Tomasz Bednarczuk Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Piotr Miśkiewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Our retrospective study included patients with ICM exposure admitted to the National Institute of Cardiology between January 2015 and November 2019. Inclusion criteria were euthyroidism at baseline (defined as TSH level within the reference range

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000515126
Volume/Issue:
Volume 10: Issue 4
Free access
Colin M. Dayan Cardiff University School of Medicine, Heath Park, Cardiff, UK

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Vijay Panicker Department of Endocrinology, Sir Charles Gairdner Hospital, Nedlands, W.A., Australia

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history of thyroid disease [ 14 ]. Our reanalysis of this data considering only subjects with a TSH within the reference range (to exclude selection bias of subjects being put on thyroxine) again showed no association between TSH and HADS depression, in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000353777
Volume/Issue:
Volume 2: Issue 3
Free access
Dominik Spira Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Nikolaus Buchmann Department of Cardiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Marcus Dörr Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Marcello R P Markus Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Matthias Nauck German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany

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Sabine Schipf Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Joachim Spranger Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Ilja Demuth Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Charité – Universitätsmedizin Berlin, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany

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Elisabeth Steinhagen-Thiessen Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Henry Völzke German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Till Ittermann Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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with low thyroid function and prediabetes seem to be more likely to progress to type 2 diabetes compared to those with prediabetes and thyroid hormone levels in the reference range ( 6 ). The effects of subclinical hypo- or hyperthyroidism on glucose

Article Type:
Research Article
Collections:
Metabolic and cardiovascular effects of thyroid hormone
DOI:
https://doi.org/10.1530/ETJ-21-0063
Volume/Issue:
Volume 11: Issue 2
Open access
Salman Razvi Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

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Bronia Arnott Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

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Dawn Teare Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

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Shaun Hiu Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

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Nicki O’Brien Department of Psychology, Northumbria University, Newcastle upon Tyne, United Kingdom

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Simon H. Pearce Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

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Introduction Subclinical hypothyroidism (SCH) is a mild form of thyroid failure diagnosed when serum TSH levels are high and circulating thyroid hormones are within the reference range [ 1 , 2 ]. The prevalence of SCH increases with age and

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1159/000509228
Volume/Issue:
Volume 10: Issue 4
Free access
Inge Bülow Pedersen Department of Endocrinology and Medicine, Aalborg University Hospital, Aalborg, Denmark

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Peter Laurberg Department of Endocrinology and Medicine, Aalborg University Hospital, Aalborg, Denmark

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function tests were available and pointed in the direction of neonatal hyperthyroidism with a suppressed serum TSH and triiodothyronine (T3) and thyroxine (T4) levels just below the upper limit of the age-specific reference range [ 6 ] (table 1 ). However

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000448034
Volume/Issue:
Volume 5: Issue 3
Free access
Paolo Cavarzere Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy

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Laura Palma Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy

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Lara Nicolussi Principe Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy

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Monica Vincenzi Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy

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Silvana Lauriola Neonatal Intensive Cure Unit, Department of Pediatrics, University Hospital of Verona, Verona, Italy

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Rossella Gaudino Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy

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Virginia Murri Pediatric Division, Hospital of San Bonifacio, Verona, Italy

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Luigi Lubrano Pediatric Division, Hospital of Legnago, Verona, Italy

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Giuliana Rossi Pediatric Division, Hospital of Mestre, Venezia, Italy

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Alessia Sallemi Pediatric Division, Hospital of Venezia, Venezia, Italy

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Ermanna Fattori Pediatric Division, Hospital of Negrar, Verona, Italy

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Marta Camilot Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy

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Franco Antoniazzi Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for the Diagnosis and Treatment of Children and Adolescents Rare Skeletal Disorders, Pediatric Clinic, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy

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( 17 , 18 ), we considered thyroid function as normal in the newborn when FT4 was in the reference range in the presence of a TSH level below 6 mU/L; in these cases, no further tests were required. When FT4 was in the reference range and TSH level was

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1530/ETJ-22-0060
Volume/Issue:
Volume 11: Issue 5
Open access
Jan Debeij Departments of Clinical Epidemiology, Leiden University Medical Centre, Leiden

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Suzanne C. Cannegieter Departments of Clinical Epidemiology, Leiden University Medical Centre, Leiden
Departments of Thrombosis and Haemostasis, Leiden University Medical Centre, Leiden

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Bregje van Zaane Departments of Internal Medicine, Slotervaart Hospital
Department of Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands

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Anton P. van Zanten Departments of Clinical Biochemistry, Slotervaart Hospital

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Frits R. Rosendaal Departments of Clinical Epidemiology, Leiden University Medical Centre, Leiden
Departments of Thrombosis and Haemostasis, Leiden University Medical Centre, Leiden
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden

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Victor E.A. Gerdes Departments of Internal Medicine, Slotervaart Hospital
Department of Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands

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Pieter H. Reitsma Departments of Thrombosis and Haemostasis, Leiden University Medical Centre, Leiden
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden

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Olaf M. Dekkers Departments of Clinical Epidemiology, Leiden University Medical Centre, Leiden
Departments of Endocrinology and Metabolism, Leiden University Medical Centre, Leiden

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in serum and plasma (regression coefficients: β ≥0.92). The laboratories' reference range in plasma was 10-24 pmol/l for fT 4 and 0.32-4.32 mU/l for TSH. Statistical Analysis The fT 4 results were returned by the routine laboratory in round

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000357578
Volume/Issue:
Volume 3: Issue 1
Free access
Simon H.S. Pearce Institute of Genetic Medicine, Newcastle University and Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK;

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Mario Vaisman Department of Endocrinology, Faculdade de Medicina, UFRJ, Rio de Janeiro, Brazil;

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Jean-Louis Wemeau Clinique Endocrinologique Marc Linquette, CHU, Lille, France

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Introduction Subclinical hypothyroidism (SCH) is defined by an elevation of the serum TSH with circulating free thyroid hormone concentrations that are within the reference range [ 1 ]. It is a common issue in clinical practice that

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000335964
Volume/Issue:
Volume 1: Issue 1
Free access
Kris Poppe Endocrine Unit, Department of Internal Medicine, University Hospital UZ Brussel (VUB), Brussels, Belgium

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Alicja Hubalewska-Dydejczyk Department of Endocrinology, Jagiellonian University Medical College, Kraków, Poland

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Peter Laurberg Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark

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Roberto Negro Division of Endocrinology, V. Fazzi Hospital, Lecce

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Francesco Vermiglio Cattedra di Endocrinologia, Policlinico Universitario, Messina, Italy

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Bijay Vaidya Department of Endocrinology, Royal Devon & Exeter Hospital, Exeter, UK

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high human chorionic gonadotrophin secretion in the first half of pregnancy is associated with a downward shift of the serum TSH and therefore a need to use trimester-specific reference ranges for serum TSH [ 4 ]. Retrospective studies have shown that

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000336101
Volume/Issue:
Volume 1: Issue 1
Free access