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Jeppe Lerche la Cour Center for Endocrinology and Metabolism, Department of Internal Medicine, Herlev and Gentofte Hospitals, Herlev, Denmark

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Line Tang Møllehave Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Capital Region, Denmark

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Bjarke Røssner Medici Center for Endocrinology and Metabolism, Department of Internal Medicine, Herlev and Gentofte Hospitals, Herlev, Denmark

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Christian Zinck Jensen Center for Endocrinology and Metabolism, Department of Internal Medicine, Herlev and Gentofte Hospitals, Herlev, Denmark

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Anne Ahrendt Bjerregaard Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Capital Region, Denmark

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Birte Nygaard Center for Endocrinology and Metabolism, Department of Internal Medicine, Herlev and Gentofte Hospitals, Herlev, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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hormones in hypothyroid and euthyroid patients: a 2020 THESIS questionnaire survey of members of the Danish Endocrine Society . Journal of Endocrinological Investigation 2021 44 2435– 2444 . ( https://doi.org/10.1007/s40618-021-01555-y ) 12 Planck T

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Diogo Mendes Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal

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Carlos Alves Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal

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Nuno Silverio Merck S.A., Algés, Portugal

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Francisco Batel Marques Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal

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. Main characteristics of studies selected for systematic review The report of selected articles results from cross-sectional analysis of 8 population-based surveys [ 15 - 18 , 40 - 42 , 49 ], 7 prospective cohort studies [ 34 , 38 , 39 , 44

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George J. Kahaly Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, Germany

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Luigi Bartalena Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Lazlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Laurence Leenhardt Thyroid and Endocrine Tumors Unit, Pitié Salpêtrière Hospital, Sorbonne University, Paris, France

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Kris Poppe Endocrine Unit, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Simon H. Pearce Department of Endocrinology, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

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storm as unlikely. Nationwide surveys in Japan have revealed the high morbidity and mortality rates of this condition and have subsequently offered a multimodality treatment, including intravenous MMI or PTU (40 or 400 mg every 8 h), glucocorticoids

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Peter N. Taylor Thyroid Research Group, Institute of Experimental and Molecular Medicine, School of Medicine, Cardiff University, Cardiff
London School of Hygiene and Tropical Medicine, London

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Bijay Vaidya Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter, UK

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/94) in children after paracetamol, valproic acid and isoniazid. Intriguingly, there were no reported cases of acute liver failure secondary to PTU in a large survey (n = 949) of acute liver failure in Scotland [ 45 ], suggesting that more data are needed

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Anthony P. Weetman Department of Human Metabolism, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK

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in the aetiology of Hashimoto thyroiditis comes from epidemiological studies. The 10-fold increase in the incidence of Hashimoto thyroiditis over three decades in Sicily can only be the result of environmental changes [ 35 ]. A histological survey of

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Darshan Patil Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Abhay Kumaraswamy Kattepur Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Srinivas Kodaganur Gopinath Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Shivanand Swamy Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Amarendra Shankarappa Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Gopinath Kodaganur Srinivasachar Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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-pathological study of 227 cases. Arch Ophthalmol 1974;92:276-286. 10.1001/archopht.1974.01010010286003 4412321 8 Shields CL, Shields JA, Gross NE, et al: Survey of 520 eyes with uveal metastases. Ophthalmology 1997;104:1265-1276. 10.1016/S0161

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Stine Linding Andersen Departments of Endocrinology, Aalborg, Denmark
Departments of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Peter Laurberg Departments of Endocrinology, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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24 Caldwell KL, Pan Y, Mortensen ME, Makhmudov A, Merrill L, Moye J: Iodine status in pregnant women in the National Children's Study and in U.S. women (15-44 years), National Health and Nutrition Examination Survey 2005-2010. Thyroid 2013

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Tomohiro Kikuchi Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan

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Shouhei Hanaoka Department of Radiology, The University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Takahiro Nakao Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Yukihiro Nomura Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan

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Takeharu Yoshikawa Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Ashraful Alam Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Harushi Mori Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan

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Naoto Hayashi Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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segmentation in the entire data set. Of the 4648 males and 2365 females included in the analysis, 2.1% of males and 3.7% of females had hypothyroidism, and 4.2% of males and 3.0% of females had hyperthyroidism ( Fig. 2 , Table 2 ). In community surveys, the

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Stamatina Ioakim CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus
Medical School, University of Milan, Milan, Italy

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Akheel A Syed Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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George Zavros CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus

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Michalis Picolos Alithias Endocrinology Centre, Nicosia, Cyprus

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Luca Persani Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Angelos Kyriacou CEDM, Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus
Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Medical School, European University of Cyprus, Nicosia, Cyprus

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/malignancy that could be missed if this threshold was raised. A recent survey administered to physicians of five professional societies addressing the clinical management of thyroid nodules demonstrated the disparity that exists regarding the adoption of

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Lars Folkestad Department of Endocrinology, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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Frans Brandt Department of Internal Medicine, Hospital of Southern Jutland, Sønderborg, Denmark

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Thomas Brix Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Marianne Vogsen Department of Oncology, Odense University Hospital, Odense, Denmark

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Lars Bastholt Department of Oncology, Odense University Hospital, Odense, Denmark

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Peter Grupe Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark

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Jeanette  Krogh Petersen Department of Clinical Pathology, Odense University Hospital, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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goitre in the elderly population in a low iodine intake area vs. high incidence of Graves’ disease in the young in a high iodine intake area: comparative surveys of thyrotoxicosis epidemiology in East-Jutland Denmark and Iceland. J Intern Med 1991; 229

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