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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen J. Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Kristian H. Winther Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Selenium (Se) deficiency has been associated with a number of diseases [ 1 ], including thyroid diseases such as goiter, hypothyroidism, and autoimmune thyroiditis [ 2 ]. Se is an essential micronutrient that is incorporated into biologically

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Line Tang Møllehave Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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Allan Linneberg Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark

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Tea Skaaby Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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Nils Knudsen Department of Endocrinology, Bispebjerg University Hospital, University of Copenhagen, Copenhagen, Denmark

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Lars Ehlers Danish Center for Healthcare Improvements, Department of Business and Management, Aalborg University, Aalborg, Denmark

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Torben Jørgensen Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark
Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Faculty of Medicine, Aalborg University, Aalborg, Denmark

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Betina Heinsbæk Thuesen Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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intake are associated with lower risk of autoimmune hypothyroidism [ 32 ] but not to an extent that explains the steep increase in thyroid hormone therapy. Vandevijvere et al. [ 7 ] applied the development in thyroid nodular disease prevalence observed

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Christophe Ghys Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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Michel Depierreux Departments of Pathology, Brussels, Belgium

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Elçin Ozalp Departments of Nuclear Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium

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Brigitte Velkeniers Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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autoimmune thyroid disease and Graves' ophthalmopathy. A sclerosing variant of Hashimoto's thyroiditis with histopathological features resembling the IgG4-related variant of the disease was reported by Li et al. [ 11 ]. Immunostaining of IgG4 in Hashimoto

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Mahdi Kamoun Endocrinology and Metabolism Department

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Michèle d'Herbomez Department of Nuclear Medicine, Lille University Hospital, Lille

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Christine Lemaire Department of Endocrinology, Regional Hospital of Béthune, Béthune

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Armelle Fayard Endocrinology and Metabolism Department

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Rachel Desailloud Endocrinology and Metabolism Department, Amiens University Hospital, Amiens, France

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Damien Huglo Department of Nuclear Medicine, Lille University Hospital, Lille

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Jean-Louis Wemeau Endocrinology and Metabolism Department

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Introduction Thyroid-stimulating hormone (TSH)-secreting pituitary adenoma (TSHoma) is a rare tumor and represents less than 2% of all pituitary tumors [ 1 , 2 , 3 ]. The coexistence of autoimmune thyroid disease and TSHoma

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Lise Husted Department of Clinical Biochemistry, Viborg Regional Hospital, Viborg, Denmark

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Sidsel Rødgaard-Hansen Department of Clinical Biochemistry, Viborg Regional Hospital, Viborg, Denmark

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Maja Hjelm Lundgaard Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Nanna Maria Uldall Torp Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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intervals for CysC and creatinine within the cohort and evaluated the association between levels of CysC, creatinine, and maternal hypothyroidism, while considering measurement of thyroid autoantibodies as marker of autoimmune thyroid disease

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Zoë Y.G.J. van Lierop Department of Neurology, Maastricht University Medical Centre, Maastricht, The Netherlands

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Sander Jentjens Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands

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Monique H.M.E. Anten Department of Neurology, Maastricht University Medical Centre, Maastricht, The Netherlands
Neurofibromatosis Expert Team, Maastricht University Medical Centre, Maastricht, The Netherlands

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Roel Wierts Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands

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Connie T. Stumpel Neurofibromatosis Expert Team, Maastricht University Medical Centre, Maastricht, The Netherlands
Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, The Netherlands

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Bas Havekes Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands

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Marinus J.P.G. van Kroonenburgh Neurofibromatosis Expert Team, Maastricht University Medical Centre, Maastricht, The Netherlands
Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands

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primary (autoimmune) thyroid disease, and the numbers lost to follow-up make our conclusions not firm but only indicative. Conclusions In the present form our study did not show an increased risk of thyroid pathology in NF1 patients. Active

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Noel Rose was an immunologist, not an endocrinologist, but we are privileged that his pioneering work which led to the discovery of autoimmune diseases was focused on the thyroid, giving our specialty a central role in the elucidation of

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Zoe A. Efstathiadou Department of Endocrinology, ‘Hippokration' General Hospital of Thessaloniki, Thessaloniki, Greece

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Albana Sykja Department of Endocrinology, ‘Hippokration' General Hospital of Thessaloniki, Thessaloniki, Greece

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Panagiotis Anagnostis Department of Endocrinology, ‘Hippokration' General Hospital of Thessaloniki, Thessaloniki, Greece

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Athanasios Panagiotou Department of Endocrinology, ‘Hippokration' General Hospital of Thessaloniki, Thessaloniki, Greece

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Marina Kita Department of Endocrinology, ‘Hippokration' General Hospital of Thessaloniki, Thessaloniki, Greece

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What Is Known about This Topic? • New onset and exacerbation of autoimmune thyroid disease have been described after successful treatment of endogenous hypercortisolism. What Does This Case Report Add? • It seems that correction of

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Ringo Manta Department of Nuclear Medicine, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Charlotte Martin Department of Infectious Diseases, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Vinciane Muls Department of Gastroenterology and Endoscopy, CHU Saint-Pierre, University Libre de Bruxelles (ULB), Brussels, Belgium

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Kris G Poppe Department of Endocrinology, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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count and electrolytes were otherwise normal, as were tests of coagulation and renal function tests. Thyroid function tests were repeated 2 days and 2 weeks later, confirming hyperthyroidism. Assessment for autoimmune thyroid disease was performed in

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Michele Marinò Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, University of Pisa, Pisa

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Claudio Marcocci Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, University of Pisa, Pisa

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Paolo Vitti Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, University of Pisa, Pisa

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Luca Chiovato Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Scientifici Maugeri IRCCS, University of Pavia, Pavia

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Luigi Bartalena Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy

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- Italian Chapter) on the use of selenium in thyroid disease. Both Negro et al. [ 1 ] and, especially, Hegedüs et al. [ 2 ], in the accompanying Editorial [ 1 , 2 ], underscored the abuse of selenium in thyroid disease. There is no question that the use

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