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Peter Taylor Departments of Diabetes and Endocrinology, Royal United Hospital, Bath
Centre for Endocrine and Diabetes Sciences, Department of Medicine, Cardiff University School of Medicine, Cardiff, UK

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Sandip Bhatt Departments of Gastroenterology, Royal United Hospital, Bath

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Ravi Gouni Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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Jonathan Quinlan Departments of Gastroenterology, Royal United Hospital, Bath

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Tony Robinson Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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are contraindicated. Case Report A 32-year-old with no clinical risk factors or evidence of pre-existing liver disease was diagnosed with Graves’ disease at week 4 in pregnancy. Her thyroid function tests revealed thyroid-stimulating hormone

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000336071
Volume/Issue:
Volume 1: Issue 1
Free access
Bernadette Biondi Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy

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Luigi Bartalena Department of Clinical and Experimental Medicine, University of Insubria, Endocrine Unit, Ospedale di Circolo, Varese, Italy

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David S. Cooper Division of Endocrinology, Diabetes, and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Md., USA

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Peter Laurberg Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark

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George J. Kahaly Department of Medicine I, Johannes Gutenberg University Medical Center, Mainz, Germany

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defined biochemically by a subnormal serum thyroid-stimulating hormone (TSH) level, with normal levels of free thyroxine (FT 4 ), triiodothyronine (TT 3 ) and/or free triiodothyronine (FT 3 ) [ 1 , 2 , 3 , 4 , 5 , 6 ]. Current assays can detect TSH

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000438750
Volume/Issue:
Volume 4: Issue 3
Free access
Federica D’Aurizio Department of Laboratory Medicine, Institute of Clinical Pathology, University Hospital of Udine, Udine, Italy

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Alessia Biasotto Department of Medicine, University of Udine, Udine, Italy

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Claudia Cipri Endocrinology, Metabolism and Clinical Nutrition Unit, University Hospital of Udine, Udine, Italy

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Franco Grimaldi Endocrinology, Metabolism and Clinical Nutrition Unit, University Hospital of Udine, Udine, Italy

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Jessica Zucco Department of Laboratory Medicine, Institute of Clinical Pathology, University Hospital of Udine, Udine, Italy

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Stefania Marzinotto Department of Laboratory Medicine, Institute of Clinical Pathology, University Hospital of Udine, Udine, Italy

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Francesco Curcio Department of Laboratory Medicine, Institute of Clinical Pathology, University Hospital of Udine, Udine, Italy
Department of Medicine, University of Udine, Udine, Italy

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Salvatore Benvenga Department of Clinical and Experimental Medicine, Endocrinology Section, University of Messina, Messina, Italy

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determination is still prone to at least six main types of analytical interference: macro thyroid-stimulating hormone (TSH), heterophilic antibodies, anti-streptavidin antibodies, anti-ruthenium antibodies, biotin and antibodies against triiodothyronine (T3) and

Article Type:
Case Report
Collections:
Thyroid function tests
DOI:
https://doi.org/10.1530/ETJ-21-0088
Volume/Issue:
Volume 11: Issue 3
Open access
Till Ittermann Institute for Community Medicine, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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Roberto Lorbeer Institute for Community Medicine, Germany

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Daniel Tiller Institute of Medical Epidemiology, Biostatistics and Informatics, Germany

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Ina Lehmphul Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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Alexander Kluttig Institute of Medical Epidemiology, Biostatistics and Informatics, Germany

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Stephan B. Felix Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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Karl Werdan Department of Medicine III, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Karin Halina Greiser German Cancer Research Centre, Division of Cancer Epidemiology, Heidelberg, Germany

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Josef Köhrle Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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Henry Völzke Institute for Community Medicine, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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Marcus Dörr Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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is only limited data on the potential linkage between thyroid dysfunction and PAD as one of the major atherosclerotic diseases. One study reported a significantly higher prevalence of increased serum thyroid-stimulating hormone (TSH) concentrations in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000381309
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Gerd Krause Structural Biology, Leibniz-Forschungsinstitut für molekulare Pharmakologie (FMP), Berlin, Germany

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Anja Eckstein Department of Ophthalmology, University Hospital Essen, Essen, Germany

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Ralf Schülein Protein Trafficking, Leibniz-Forschungsinstitut für molekulare Pharmakologie (FMP), Berlin, Germany

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Introduction TSH-Receptor, Graves’ Disease and Graves’ Orbitopathy The thyrotropin receptor or thyroid-stimulating hormone (TSH) receptor (TSHR) is mainly expressed in follicular epithelial cells of the thyroid gland [ 1 ]. TSHR activation

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000511871
Volume/Issue:
Volume 9: Issue 1_Suppl
Free access
Hirosuke Danno Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Eijun Nishihara Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Kazuyoshi Kousaka Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Tomohiko Nakamura Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Toshihiko Kasahara Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Takumi Kudo Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Mitsuru Ito Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Shuji Fukata Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Mitsushige Nishikawa Division of Internal Medicine, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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Akira Miyauchi Division of Surgery and Director, Center for Excellence in Thyroid Care, Kuma Hospital, Kobe, Japan

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]. Materials and Methods Patients This study involved patients who visited our hospital between February 2005 and August 2019. Thyrotoxicosis was diagnosed when the thyroid-stimulating hormone (TSH) concentration was ≤0.1 μU/mL, and FT4 and/or FT3 level

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000510312
Volume/Issue:
Volume 10: Issue 6
Open access
Beatrice Engelmann Interfaculty Institute for Genetics and Functional Genomics, Germany

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Julia Bischof Interfaculty Institute for Genetics and Functional Genomics, Germany

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Anne-Luise Dirk Experimental and Clinical Endocrinology, Med Clinic I, University of Lübeck, Lübeck, Germany

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Nele Friedrich Institute for Clinical Chemistry and Laboratory Medicine, Germany

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Elke Hammer Interfaculty Institute for Genetics and Functional Genomics, Germany

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Thomas Thiele Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany

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Dagmar Führer Clinic for Endocrinology and Metabolic Disorders, University Clinics Essen, Essen, Germany

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Georg Homuth Interfaculty Institute for Genetics and Functional Genomics, Germany

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Georg Brabant Experimental and Clinical Endocrinology, Med Clinic I, University of Lübeck, Lübeck, Germany

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Uwe Völker Interfaculty Institute for Genetics and Functional Genomics, Germany

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.e. thyroid-stimulating hormone (TSH)], free triiodothyronine (fT 3 ) and free thyroxine (fT 4 ) were measured using immunoassays. Sex hormone-binding globulin (SHBG) as well as FIX and FXIII subunit B concentrations were determined in EDTA plasma using a

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000381769
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Wenxing Guo The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Long Tan The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Shuyao Dong The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Ya Jin The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Mei Zhu The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China

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Hongyan Wei The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China

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Yanting Chen The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Lili Fan The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Cong Du The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China

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Wanqi Zhang The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China
The Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China
Tianjin Key Laboratory of Environment, Nutrition and Public Health, Tianjin, China
Center for International Collaborative Research on Environment, Nutrition and Public Health, Tianjin, China

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stored in a clean glass tube. Samples were spun and the serum was separated within 2 h from taking the blood sample, and the aliquots were frozen at −20°C until further analysis. The concentrations of thyroid-stimulating hormone (TSH) were measured with

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000513494
Volume/Issue:
Volume 10: Issue 6
Free access
Laura Croce Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy

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Fausta Beneventi Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy

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Federica Ripepi Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy

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Irene De Maggio Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy

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Alberto Malovini Istituti Clinici Scientifici Maugeri IRCCS, Laboratory of Informatics and Systems Engineering for Clinical Research, Pavia (PV), Italy

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Camilla Bellingeri Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy

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Francesca Coperchini Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy

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Marsida Teliti Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy

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Mario Rotondi Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy

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Arsenio Spinillo Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy

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Flavia Magri Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy

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; TSH, thyroid-stimulating hormone. Evaluation of the potential impact of a TSH value ≥4 mU/L on UtA-PI according to BMI To evaluate the impact of increased TSH on early placentation among women with different BMI we compared the values

Article Type:
Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-23-0213
Volume/Issue:
Volume 13: Issue 2
Open access
Bushra Shahida Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden

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Tereza Planck Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden
Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden

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Peter Åsman Department of Clinical Sciences, Ophthalmology, Lund University, Malmö, Sweden
Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden

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Mikael Lantz Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden
Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden

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presence of thyroid-stimulating hormone (TSH)-receptor antibodies (TRAb) and/or diffuse uptake by technetium scintigraphy. GO diagnosis was made by an endocrinologist and/or ophthalmologist based on the presence of clinical signs, as previously described

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000490892
Volume/Issue:
Volume 7: Issue 6
Free access