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from the follicular carcinoma of the thyroid. Introduction Well-differentiated thyroid cancers include both the papillary and follicular varieties. Follicular thyroid cancers are more aggressive than their papillary counterparts with
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How It is useful for the pathologist to first analyse surgical specimens of thyroid tissue with common diseases such as goitre, thyroiditis, and papillary thyroid carcinoma, as well as ‘histologically normal' tissue, analysing them under high
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. Lymphocytic infiltration in nontumoral tissue was detected in 32 patients (62.7%). Despite not being statistically significant, this rate was considered to be high. The majority of the patients (n = 45, 88.2%) had conventional papillary thyroid carcinoma, but
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal
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papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, and oncocitic cell carcinoma of the thyroid ( 5 ). PTC is the most common histological subtype of differentiated thyroid malignancy, constituting about 80% of cases ( 6 ). The age of
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. Although rare, FNA may detect uncommon tumors (such as medullary carcinoma or aggressive variants of papillary thyroid cancer) that are not candidates for active surveillance [ 2 ]. Disclosure Statement No competing financial interests exist
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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seen as a protective condition for thyroid cancer, and a relationship between low serum TSH levels and a lower incidence of papillary carcinoma has been suggested [ 6 , 7 ]. However, a recent meta-analysis could not confirm this association [ 8
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Differentiated thyroid carcinoma (DTC) accounts for more than 80% of all thyroid cancers. An increasing incidence of DTC over the last decades has been reported worldwide, and is mainly due to the discovery of small papillary carcinomas [ 1
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Introduction Papillary carcinoma is the most common histopathologic type of malignancy of the thyroid [ 1 ]. Papillary microcarcinoma (PMC) is defined as a thyroid cancer measuring ≤1 cm in greatest diameter by the World Health Organization
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Department of Medicine, University of Alcalá de Henares, Madrid
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IdiSNA (Instituto de investigación en la salud de Navarra), Pamplona, Spain
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in the diagnosis of papillary thyroid carcinoma: improvement in the sensitivity or specificity? J Int Med Res 2013;41:975-983. 8 Das DK, Al-Waheeb SKM, George SS, Haji BI, Mallik MK: Contribution of immunocytochemical stainings for galectin-3
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Nikiforova MN , Kimura ET , Gandhi M , Biddinger PW , Knauf JA , Basolo F , . BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas . J Clin
