Cengiz Kara
Cengiz Kara
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Pediatric Endocrinology, Faculty of Medicine, Istinye University, Istanbul, Turkey
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Department of Pediatric Endocrinology, Faculty of Medicine, Istinye University, Istanbul, Turkey
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Jamala Mammadova
Jamala Mammadova
Pediatric Endocrinology Unit, Altinbas University Medicalpark Bahçelievler Hospital, Istanbul, Turkey
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Ümmet Abur
Ümmet Abur
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Cagri Gumuskaptan
Cagri Gumuskaptan
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Elif İzci Güllü
Elif İzci Güllü
Department of Pediatric Endocrinology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Ayhan Dağdemir
Ayhan Dağdemir
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
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Murat Aydın
Murat Aydın
Department of Pediatric Endocrinology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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did they address patients with TCH. Current consensus guidelines on CH recommend that genetic testing should aim to improve diagnosis, treatment or prognosis of the patients ( 13 ). But it is unclear which patients would benefit most from such a
Jesper Karmisholt
Jesper Karmisholt
Department of Medical Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Clinical Institute, Aalborg University, Aalborg, Denmark
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Clinical Institute, Aalborg University, Aalborg, Denmark
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Stig Andersen
Stig Andersen
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
Clinical Institute, Aalborg University, Aalborg, Denmark
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Clinical Institute, Aalborg University, Aalborg, Denmark
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or no effect of L-T4 treatment on quality of life and other parameters [ 6 , 7 ]. Still, guidelines from both Europe and North America suggest that SCH patients with TSH between 4 and 10 mU/L and symptoms associated with hypothyroidism should receive
Kevin Stroek
Kevin Stroek
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Annemieke C. Heijboer
Annemieke C. Heijboer
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands
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Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands
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Marja van Veen-Sijne
Marja van Veen-Sijne
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Annet M. Bosch
Annet M. Bosch
Division of Metabolic Disorders, Department of Pediatrics, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Catharina P.B. van der Ploeg
Catharina P.B. van der Ploeg
Department of Child Health, Netherlands Organization for Applied Scientific Research TNO, Leiden, The Netherlands
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Nitash Zwaveling-Soonawala
Nitash Zwaveling-Soonawala
Department of Paediatric Endocrinology, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Robert de Jonge
Robert de Jonge
Department of Clinical Chemistry, Amsterdam UMC, Vrije Universiteit & University of Amsterdam, Amsterdam, The Netherlands
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A.S. Paul van Trotsenburg
A.S. Paul van Trotsenburg
Department of Paediatric Endocrinology, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Anita Boelen
Anita Boelen
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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the Clinical & Laboratory Standards Institute (CLSI) guidelines, a sample size of at least 120 reference subjects is required per category [ 7 ]. In order to establish RIs divided by sex (categories: males and females) and NBS sampling age after birth
Laura Fugazzola
Laura Fugazzola
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Maurilio Deandrea
Maurilio Deandrea
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Stefano Borgato
Stefano Borgato
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Marco Dell’Acqua
Marco Dell’Acqua
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Francesca Retta
Francesca Retta
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Alberto Mormile
Alberto Mormile
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Chiara Carzaniga
Chiara Carzaniga
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Giacomo Gazzano
Giacomo Gazzano
Pathology Unit, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Gabriele Pogliaghi
Gabriele Pogliaghi
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Marina Muzza
Marina Muzza
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Luca Persani
Luca Persani
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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). According to the European Thyroid Association guidelines (ETA GLs) for image-guided ablation in benign thyroid nodules, one or two benign cytologic results are needed before the procedure, and the treatment is not recommended for nodules with high-risk US
Giovanni Mauri
Giovanni Mauri
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, Denmark
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Steven Bandula
Steven Bandula
Interventional Oncology Service, University College Hospital, London, United Kingdom
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Roberto Luigi Cazzato
Roberto Luigi Cazzato
Department of Interventional Radiology, University Hospital of Strasbourg, Strasbourg, France
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Agnieszka Czarniecka
Agnieszka Czarniecka
The Oncologic and Reconstructive Surgery Clinic, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
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Oliver Dudeck
Oliver Dudeck
Center for Microtherapy, Klinik Hirslanden, Zurich, Switzerland
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Laura Fugazzola
Laura Fugazzola
Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Romana Netea-Maier
Romana Netea-Maier
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Gilles Russ
Gilles Russ
Thyroid and Endocrine Tumors Unit, La Pitie-Salpetriere Hospital, Sorbonne University, Paris, France
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Göran Wallin
Göran Wallin
Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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Enrico Papini
Enrico Papini
Department of Endocrinology & Metabolism, Ospedale Regina Apostolorum, Albano, Italy
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lymph-node recurrences, current thyroid cancer guidelines suggest considering AS for cervical nodal metastases with a diameter ≤10 mm that appear as slow-growing [ 4 ]. As an alternative option, various image-guided MITs are now proposed as outpatient
Selwan Khamisi
Selwan Khamisi
Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden
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Peter Lindgren
Peter Lindgren
Women's and Children's Health, University Hospital, Uppsala University, Uppsala, Sweden
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F. Anders Karlsson
F. Anders Karlsson
Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden
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guidelines on dosing intra-amniotic injections of thyroxine and monitoring effects of treatment should be produced in a collaborative effort. Disclosure Statement All authors declare that there is no conflict of interest that could be perceived as
Liyun Shen
Liyun Shen
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Lei Ye
Lei Ye
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Wei Zhu
Wei Zhu
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Qin Jiao
Qin Jiao
Department of Ophthalmology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Yulin Zhou
Yulin Zhou
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shu Wang
Shu Wang
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Weiqing Wang
Weiqing Wang
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Guang Ning
Guang Ning
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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, 5 , 6 ), guidelines recommended that a 4.5 g weekly pulse i.v. methylprednisolone (ivMP) remains to be the more accessible and cost-effective choice for active and moderate-to-severe GO patients currently ( 7 ). In previous studies, the response
Caroline M J van Kinschot
Caroline M J van Kinschot
Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Ivona Lončar
Ivona Lončar
Academic Center for Thyroid Diseases, Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands
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Tessa M van Ginhoven
Tessa M van Ginhoven
Academic Center for Thyroid Diseases, Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands
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W Edward Visser
W Edward Visser
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Robin P Peeters
Robin P Peeters
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Charlotte van Noord
Charlotte van Noord
Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands
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the Thyroid Network Study Group †
the Thyroid Network Study Group
the Thyroid Network Study Group †
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, calcium supplementation is not without risks, patients are exposed to adverse effects related to calcium supplementation, including kidney stones, constipation, heartburn, and hypercalcemia ( 8 ). Standardized guidelines for postoperative calcium
L.A. Jonker
L.A. Jonker
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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C.A. Lebbink
C.A. Lebbink
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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M.C.J. Jongmans
M.C.J. Jongmans
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
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R.A.J. Nievelstein
R.A.J. Nievelstein
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Pediatric Radiology and Nuclear Medicine, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Pediatric Radiology and Nuclear Medicine, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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J.H.M. Merks
J.H.M. Merks
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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E.J.M. Nieveen van Dijkum
E.J.M. Nieveen van Dijkum
Department of Surgery, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands
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T.P. Links
T.P. Links
Department of Endocrinology, University Medical Center Groningen, Groningen, The Netherlands
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N. Hoogerbrugge
N. Hoogerbrugge
Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands
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A.S.P. van Trotsenburg
A.S.P. van Trotsenburg
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands
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H.M. van Santen
H.M. van Santen
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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the age of 16 years onwards, or earlier in case of a family history for DTC or after informed discussion with the patient and its family [ 5 ]. Although these guidelines agree on once a year surveillance frequency, they are discordant with regard to
Jacqueline Jonklaas
Jacqueline Jonklaas
Division of Endocrinology, Georgetown University, Washington, District of Columbia, USA
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Antonio C. Bianco
Antonio C. Bianco
Section of Adult and Pediatric Endocrinology and Metabolism, University of Chicago, Chicago, Illinois, USA
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Anne R. Cappola
Anne R. Cappola
Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Francesco S. Celi
Francesco S. Celi
Division of Endocrinology, Diabetes and Metabolism, Virginia Commonwealth University, Richmond, Virginia, USA
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Eric Fliers
Eric Fliers
Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Center, Amsterdam, The Netherlands
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Heike Heuer
Heike Heuer
Department of Endocrinology, Diabetes and Metabolism, University Duisburg-Essen, Essen, Germany
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Elizabeth A. McAninch
Elizabeth A. McAninch
Division of Endocrinology, Rush University, Chicago, Illinois, USA
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Lars C. Moeller
Lars C. Moeller
Department of Endocrinology, Diabetes and Metabolism, University Duisburg-Essen, Essen, Germany
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Birte Nygaard
Birte Nygaard
Center for Endocrinology and Metabolism, Department of Internal Medicine, Herlev and Gentofte Hospitals, Herlev, Denmark
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Anna M. Sawka
Anna M. Sawka
Division of Endocrinology, University Health Network and University of Toronto, Toronto, Ontario, Canada
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Torquil Watt
Torquil Watt
Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
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Colin M. Dayan
Colin M. Dayan
Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom
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Consensus Document was approved by the ATA Board of Directors, and the ATA Guidelines and Statements Committee, who also reviewed and approved the conflict of interest management plan. The near-final article was approved by the relevant committees of the ATA
