Filter

Refine by date

—

Refine by collections

  • Print
  • Save

Search Results

You are looking at 71 - 80 of 387 items for :

Clear All
Steen J. Bonnema Departments of Endocrinology, Odense University Hospital, Odense

Search for other papers by Steen J. Bonnema in
Google Scholar
PubMed Close
,
Elisabeth S. Stovgaard Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

Search for other papers by Elisabeth S. Stovgaard in
Google Scholar
PubMed Close
,
Søren Fast Departments of Endocrinology, Odense University Hospital, Odense

Search for other papers by Søren Fast in
Google Scholar
PubMed Close
,
Kasper Broedbaek Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

Search for other papers by Kasper Broedbaek in
Google Scholar
PubMed Close
,
Jon T. Andersen Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

Search for other papers by Jon T. Andersen in
Google Scholar
PubMed Close
,
Allan Weimann Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

Search for other papers by Allan Weimann in
Google Scholar
PubMed Close
,
Peter Grupe Departments of Nuclear Medicine, Odense University Hospital, Odense

Search for other papers by Peter Grupe in
Google Scholar
PubMed Close
,
Laszlo Hegedüs Departments of Endocrinology, Odense University Hospital, Odense

Search for other papers by Laszlo Hegedüs in
Google Scholar
PubMed Close
, and
Henrik E. Poulsen Laboratory of Clinical Pharmacology Q7642, Rigshospitalet
Department of Clinical Pharmacology, Bispebjerg Hospital
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Henrik E. Poulsen in
Google Scholar
PubMed Close

Introduction For many years radioactive iodine ( 131 I) has been used for treatment of nontoxic goiter, hyperthyroidism and thyroid cancer. During the last decade recombinant human TSH (rhTSH) - a very potent stimulator of the thyroid 131 I

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000371883
Volume/Issue:
Volume 4: Issue 1
Free access
Lars Folkestad Department of Endocrinology, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

Search for other papers by Lars Folkestad in
Google Scholar
PubMed Close
,
Frans Brandt Department of Internal Medicine, Hospital of Southern Jutland, Sønderborg, Denmark

Search for other papers by Frans Brandt in
Google Scholar
PubMed Close
,
Thomas Brix Department of Endocrinology, Odense University Hospital, Odense, Denmark

Search for other papers by Thomas Brix in
Google Scholar
PubMed Close
,
Marianne Vogsen Department of Oncology, Odense University Hospital, Odense, Denmark

Search for other papers by Marianne Vogsen in
Google Scholar
PubMed Close
,
Lars Bastholt Department of Oncology, Odense University Hospital, Odense, Denmark

Search for other papers by Lars Bastholt in
Google Scholar
PubMed Close
,
Peter Grupe Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark

Search for other papers by Peter Grupe in
Google Scholar
PubMed Close
,
Jeanette  Krogh Petersen Department of Clinical Pathology, Odense University Hospital, Odense, Denmark

Search for other papers by Jeanette  Krogh Petersen in
Google Scholar
PubMed Close
, and
Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

Search for other papers by Laszlo Hegedüs in
Google Scholar
PubMed Close

result of interactions between genetic [ 3 ] and environmental triggers, of which cigarette smoking [ 4 , 5 ] and iodine intake [ 6 ] have received most attention. Patients with GD have an increased burden of other morbidities [ 7 ], including an

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000479061
Volume/Issue:
Volume 6: Issue 5
Free access
Elske T. Massolt Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Elske T. Massolt in
Google Scholar
PubMed Close
,
Mahdi  Salih Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Mahdi  Salih in
Google Scholar
PubMed Close
,
Carolien M. Beukhof Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Carolien M. Beukhof in
Google Scholar
PubMed Close
,
Boen L.R. Kam Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Boen L.R. Kam in
Google Scholar
PubMed Close
,
J.W. Burger Division of Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by J.W. Burger in
Google Scholar
PubMed Close
,
W. Edward Visser Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by W. Edward Visser in
Google Scholar
PubMed Close
,
Ewout J. Hoorn Department of Nephrology and Transplantation, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Ewout J. Hoorn in
Google Scholar
PubMed Close
, and
Robin P. Peeters Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Search for other papers by Robin P. Peeters in
Google Scholar
PubMed Close

Rotterdam between November 2014 and October 2015. Initial therapy consisted of total thyroidectomy. Patients were eligible for inclusion if they were scheduled for treatment with radioactive iodine (RAI); did not use drugs interfering with TH metabolism or

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000478521
Volume/Issue:
Volume 6: Issue 5
Free access
Christiaan F Mooij Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands

Search for other papers by Christiaan F Mooij in
Google Scholar
PubMed Close
,
Timothy D Cheetham Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK
Department of Pediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK

Search for other papers by Timothy D Cheetham in
Google Scholar
PubMed Close
,
Frederik A Verburg Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands

Search for other papers by Frederik A Verburg in
Google Scholar
PubMed Close
,
Anja Eckstein Department of Ophthalmology, University Duisburg Essen, Essen, Germany

Search for other papers by Anja Eckstein in
Google Scholar
PubMed Close
,
Simon H Pearce Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK
Endocrine Unit, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK

Search for other papers by Simon H Pearce in
Google Scholar
PubMed Close
,
Juliane Léger Department of Pediatric Endocrinology and Diabetes, Reference Center for Rare Endocrine Growth and Development Diseases, Endo-ERN HCP, Assistance Publique-Hôpitaux de Paris, Robert Debré University Hospital, University of Paris, NeuroDiderot Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France

Search for other papers by Juliane Léger in
Google Scholar
PubMed Close
, and
A S Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands

Search for other papers by A S Paul van Trotsenburg in
Google Scholar
PubMed Close

Introduction Purpose and scope of guideline Hyperthyroidism caused by Graves’ disease (GD) is a relatively rare disease in children. Although treatment options are the same as in adults – antithyroid drugs (ATD), radioactive iodine (RAI

Article Type:
Other
Collections:
Pediatric thyroid diseases
DOI:
https://doi.org/10.1530/ETJ-21-0073
Volume/Issue:
Volume 11: Issue 1
Open access
P. Reed Larsen Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Harvard Institutes of Medicine, Boston, Mass., USA

Search for other papers by P. Reed Larsen in
Google Scholar
PubMed Close
and
Ann Marie Zavacki Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Harvard Institutes of Medicine, Boston, Mass., USA

Search for other papers by Ann Marie Zavacki in
Google Scholar
PubMed Close

Introduction When dietary iodine is sufficient, the major product of the thyroid gland is thyroxine (T4) which is secreted at a rate of 10-fold that of 3,5,3′-triiodothyronine (T3) in humans. Thus, a rate-limiting step in thyroid hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000343922
Volume/Issue:
Volume 1: Issue 4
Free access
Francisco Sousa Santos Endocrinology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

Search for other papers by Francisco Sousa Santos in
Google Scholar
PubMed Close
,
Rita Joana Santos Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

Search for other papers by Rita Joana Santos in
Google Scholar
PubMed Close
, and
Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Faculty of Medical Sciences of Lisbon, Lisbon, Portugal

Search for other papers by Valeriano Leite in
Google Scholar
PubMed Close

Introduction Differentiated thyroid cancer (DTC) is the most common form of thyroid carcinoma [ 1 ]. Most cases of DTC can be effectively treated with surgery followed by levothyroxine therapy and radioactive iodine (RAI) in selected patients

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000501680
Volume/Issue:
Volume 8: Issue 5
Free access
Maria Rossing Department of Endocrinology, Herlev University Hospital, Herlev
Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

Search for other papers by Maria Rossing in
Google Scholar
PubMed Close
,
Birte Nygaard Department of Endocrinology, Herlev University Hospital, Herlev

Search for other papers by Birte Nygaard in
Google Scholar
PubMed Close
,
Finn Cilius Nielsen Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

Search for other papers by Finn Cilius Nielsen in
Google Scholar
PubMed Close
, and
Finn Noe Bennedbæk Department of Endocrinology, Herlev University Hospital, Herlev

Search for other papers by Finn Noe Bennedbæk in
Google Scholar
PubMed Close

patients with known or suspected nodular thyroid disease and a US-guided fine-needle aspirate (FNA) is considered the gold standard when evaluating cold (without uptake on a technetium-99m scintigraphy) thyroid nodules [ 1 ]. In a borderline iodine

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000338921
Volume/Issue:
Volume 1: Issue 2
Open access
Mathieu Spaas Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

Search for other papers by Mathieu Spaas in
Google Scholar
PubMed Close
,
Brigitte Decallonne Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

Search for other papers by Brigitte Decallonne in
Google Scholar
PubMed Close
,
Annouschka Laenen Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium

Search for other papers by Annouschka Laenen in
Google Scholar
PubMed Close
,
Jaak Billen Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

Search for other papers by Jaak Billen in
Google Scholar
PubMed Close
, and
Sandra Nuyts Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

Search for other papers by Sandra Nuyts in
Google Scholar
PubMed Close

of DTC usually consists of total thyroidectomy followed by radioactive iodine (RAI) remnant ablation (RRA). Postoperative administration of RAI serves three major goals: the first is to destroy any residual microscopic disease as well as any remaining

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000489849
Volume/Issue:
Volume 7: Issue 4
Free access
Ulrich Schweizer Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

Search for other papers by Ulrich Schweizer in
Google Scholar
PubMed Close
,
Jörg Johannes Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

Search for other papers by Jörg Johannes in
Google Scholar
PubMed Close
,
Dorothea Bayer Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

Search for other papers by Dorothea Bayer in
Google Scholar
PubMed Close
, and
Doreen Braun Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

Search for other papers by Doreen Braun in
Google Scholar
PubMed Close

. Each binding site contains several largely hydrophobic pockets formed by a main chain and side chains of β-sheets which can each accommodate one iodine atom from TH. The innermost binding pocket also allows nucleophiles (e.g. Ser-OH) to form polar

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000367858
Volume/Issue:
Volume 3: Issue 3
Free access
Georgios K. Markantes Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

Search for other papers by Georgios K. Markantes in
Google Scholar
PubMed Close
,
Marina A. Michalaki Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

Search for other papers by Marina A. Michalaki in
Google Scholar
PubMed Close
,
George A. Vagenakis Department of Pediatric Cardiology and Adult Congenital Heart Disease, Onassis Cardiac Surgery Center, Athens, Greece

Search for other papers by George A. Vagenakis in
Google Scholar
PubMed Close
,
Fotini N. Lamari Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece

Search for other papers by Fotini N. Lamari in
Google Scholar
PubMed Close
,
Efthymia Pitsi Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece

Search for other papers by Efthymia Pitsi in
Google Scholar
PubMed Close
,
Maria Eliopoulou Endocrinology Unit, Karamandanio Hospital, Patras, Greece

Search for other papers by Maria Eliopoulou in
Google Scholar
PubMed Close
,
Nicholas G. Beratis Department of Pediatrics, University of Patras Medical School, Patras, Greece

Search for other papers by Nicholas G. Beratis in
Google Scholar
PubMed Close
, and
Kostas B. Markou Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

Search for other papers by Kostas B. Markou in
Google Scholar
PubMed Close

pathogenic mechanisms: type 1 (AIT1) is a form of iodine-induced hyperthyroidism in response to the high iodine load present in amiodarone, while type 2 (AIT2) is a drug-induced destructive thyroiditis. There are also mixed forms, in which both pathogenic

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000500355
Volume/Issue:
Volume 8: Issue 4
Free access