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Zhen Gao The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Hongtao Zhang The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Lijuan Zhang The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Huimin Yu The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Xuemin Di The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Zeyang Wang The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Zezhou Liu The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Aixia Sui The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Juan Wang The First Department of Oncology, Hebei General Hospital, Shijiazhuang, China

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Gaofeng Shi Department of Radiology, The 4th Affiliated Hospital of Hebei Medical University, Shijiazhuang, China

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method to manage aggressive thyroid cancers is surgical removal of the thyroid gland (thyroidectomy) followed by radioactive iodine ablation and thyroid-stimulating hormone suppression therapy [ 3 , 4 ]. However, after successful treatment, 35% of

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Brigitte Decallonne Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Annick Van den Bruel Department of Endocrinology, General Hospital St Jan, Bruges, Belgium

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Gilles Macq Department of Research, Belgian Cancer Registry, Brussels, Belgium

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Nathalie Elaut Department of Research, Belgian Cancer Registry, Brussels, Belgium

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Harlinde De Schutter Department of Research, Belgian Cancer Registry, Brussels, Belgium

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thyroid surgery was preceded by fine-needle aspiration (FNA), suggesting less selective surgery, and the proportion of histological thyroid cancer diagnosis after total thyroidectomy was lower. Finally, in the HIR, less thyroid cancer patients had been

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Rony Ruben Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Praveen V. Pavithran Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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V. Usha Menon Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Vasantha Nair Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Harish Kumar Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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total thyroidectomy and radioactive iodine ablation at the Thyroid Cancer Clinic of our Institute and to assess which of these most accurately predicted outcomes using clinical end points. The secondary objective was to compare the performance of the

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Pedro Marques Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Maria João Bugalho Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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near-total thyroidectomy (97.6%), associated with lymph node dissections in 55 cases (21.6%). Eighty-four patients (32.9%) were operated in the Head and Neck Surgery Department of our institution. The remaining 171 patients underwent surgery at other

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Darshan Patil Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Abhay Kumaraswamy Kattepur Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Srinivas Kodaganur Gopinath Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Shivanand Swamy Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Amarendra Shankarappa Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Gopinath Kodaganur Srinivasachar Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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finger revealed metastasis from the follicular carcinoma thyroid. Chest X-ray and CT scans revealed multiple pulmonary nodules with retrosternal extension of the thyroid. Serum thyroglobulin was 28,320 ng/ml. The patient underwent total thyroidectomy

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Ian D Hay Department of Medicine 1, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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Suneetha Kaggal Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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Geoffrey B Thompson Department of Surgery, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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are convinced that at our institution, radioiodine remnant ablation (RRA), when administered after potentially curative bilateral thyroidectomy (BT) to low-risk (MACIS scores <6) adult PTC (APTC) patients, has not reduced ( 7 ) either cause

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Julia A Baran Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Mya Bojarsky Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Stephen Halada Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Julio C Ricarte-Filho Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Amber Isaza Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Aime T Franco Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Lea F Surrey Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Tricia Bhatti Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Zubair Baloch Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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N Scott Adzick Department of Surgery, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Sogol Mostoufi-Moab Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Ken Kazahaya Division of Pediatric Otolaryngology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Andrew J Bauer Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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(Epic ® ). FNA cytology was classified according to The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) ( 22 ). A two-stage thyroidectomy was defined as a lobectomy followed by a completion thyroidectomy. Prophylactic CND (level VI or levels

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Dong Jun Lim Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea

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Won Bae Kim Department of Internal Medicine, Asan Medical Center, Korea

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Bo Hyun Kim Department of Internal Medicine, Pusan National University Hospital, Busan, Korea

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Tae Yong Kim Department of Internal Medicine, Asan Medical Center, Korea

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Young Suk Jo Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea

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Ho-Cheol Kang Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea

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Young Joo Park Department of Internal Medicine, Seoul National University Hospital, Korea

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Ka Hee Yi Department of Internal Medicine, Korea Cancer Center Hospital, Korea

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Minho Shong Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea

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In Joo Kim Department of Internal Medicine, Pusan National University Hospital, Busan, Korea

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Do Joon Park Department of Internal Medicine, Seoul National University Hospital, Korea

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Sun Wook Kim Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Jae Hoon Chung Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Jaetae Lee Department of Nuclear Medicine, Kyungpook National University Hospital, Daegu, Korea

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Sung-Soo Koong Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea

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Young Kee Shong Department of Internal Medicine, Asan Medical Center, Korea

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Korea from December 2010 to May 2011. All enrolled patients underwent total thyroidectomy with or without lymph node dissection and remnant ablation as needed. The patients who had undergone a diagnostic whole body scan (WBS) or radioiodine therapy with

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Noha Mukhtar Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

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Hadeel Aljamei Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

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Abeer Aljomaiah Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

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Yosra Moria Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

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Ali S. Alzahrani Department of Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

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-total thyroidectomy with or without lymph node dissection and I-131 adjuvant therapy [ 6 , 8 ]. The risk stratification concepts were further extended to include follow-up evaluations after the initial management based on the available information at the time of

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Eun Kyung Jang Department of Endocrinology, Dongnam Institute of Radiological and Medical Sciences Cancer Center, Busan, Korea
Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Won Gu Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Hyemi Kwon Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Yun Mi Choi Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Min Ji Jeon Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Tae Yong Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Young Kee Shong Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Won Bae Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Eui Young Kim Department of Endocrinology, Dongnam Institute of Radiological and Medical Sciences Cancer Center, Busan, Korea

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thyroidectomy between 1995 and 2005 in Asan Medical Center, Seoul, Korea. Patients aged between 45 and 75 years, with tumors between 1 and 4 cm, were included in the study. We excluded patients with distant metastasis before surgery or patients with type 1

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