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Shinsuke Shinkai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kenji Ohba Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kennichi Kakudo Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Osaka, Japan

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Takayuki Iwaki Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yoshihiro Mimura Department of Internal Medicine, American Hospital of Paris, Neuilly sur Seine, France

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Akio Matsushita Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Go Kuroda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yuki Sakai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Nobuhiko Nishino Department of Surgery, Maruyama Hospital, Shizuoka, Japan

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Kazuo Umemura Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan
Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Shigekazu Sasaki Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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thyroid scintigraphy is a circumscribed hyperdense lesion surrounded by hypodense thyroid tissue. Hyperfunctioning thyroid nodules can be classified as benign or malignant, though the incidence of a hyperfunctioning cancerous nodule is extremely low [ 1

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000513552
Volume/Issue:
Volume 10: Issue 3
Free access
Marina Morais Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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João Capela-Costa Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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Luís Matos-Lima Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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José Costa-Maia Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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. All of these variations increase the risk of nerve injury during thyroidectomy. In studies on cadavers, the nonrecurrent inferior laryngeal nerve occurs very rarely, with an incidence of 0.3-0.8% [ 9 , 10 ]. In the largest series reported, including

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000438751
Volume/Issue:
Volume 4: Issue 4
Free access
Marco Capezzone Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Noemi Fralassi Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Chiara Secchi Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Silvia Cantara Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Lucia Brilli Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Tania Pilli Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Fabio Maino Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Raffaella Forleo Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Furio Pacini Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Gabriele Cevenini Department of Medical Biotechnologies, University of Siena, Siena, Italy

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Alessandra Cartocci Department of Medical Biotechnologies, University of Siena, Siena, Italy

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Maria Grazia Castagna Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Introduction The incidence of non-medullary thyroid cancer, in particular papillary thyroid cancer (PTC), has increased in many countries over the past 20 years [ 1 - 3 ]. As a consequence, also the reported incidence of the familial form of

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000506955
Volume/Issue:
Volume 9: Issue 4
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Furio Pacini Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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Differentiated thyroid carcinoma (DTC) accounts for more than 80% of all thyroid cancers. An increasing incidence of DTC over the last decades has been reported worldwide, and is mainly due to the discovery of small papillary carcinomas [ 1

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000442880
Volume/Issue:
Volume 5: Issue 1
Free access
Clare Yvonne England National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom
Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, United Kingdom

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Laura Moss Velindre Cancer Centre, Cardiff, United Kingdom

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Matthew Beasley University Hospitals Bristol NHS Trust, Bristol, United Kingdom

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Ingrid Haupt-Schott Velindre Cancer Centre, Cardiff, United Kingdom

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Georgia Herbert National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom

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Charlotte Atkinson National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom

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Background Thyroid cancer accounts for less than 1% of cancer cases in the UK. However, the incidence is increasing, and between 2014 to 2016 there were an average of 3,527 new cases of thyroid cancer annually in the UK, compared to 1,125 in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000504706
Volume/Issue:
Volume 9: Issue 3
Free access
Saleha Babli Division of Endocrinology and Metabolism, Department of Medicine, Montreal General Hospital, McGill University, Montreal, Québec, Canada
Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, Saudi Arabia

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Richard J.  Payne Department of Otolaryngology, Royal Victoria Hospital, McGill University, Montreal, Québec, Canada

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Elliot Mitmaker Department of Surgery, Montreal General Hospital, McGill University, Montreal, Québec, Canada

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Juan Rivera Division of Endocrinology and Metabolism, Department of Medicine, Montreal General Hospital, McGill University, Montreal, Québec, Canada

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in the PTC-only group. There were significantly fewer patients with persistent disease in the PTC-CLT group compared with the PTC-only group (0 vs. 8.29%, respectively; p = 0.03), and a lower incidence of CI in the PTC-CLT group compared with the

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000486367
Volume/Issue:
Volume 7: Issue 2
Free access
Leonidas H. Duntas Endocrine Unit, Evgenidion Hospital, University of Athens, Athens, Greece

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Georg Brabant Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany

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Fabio Monzani Department of Clinical and Experimental Medicine, Università di Pisa, Pisa, Italy

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Simon H.S. Pearce Institute of Genetic Medicine, Newcastle University, UK
Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Robin Patrick Peeters Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Salman Razvi Institute of Genetic Medicine, Newcastle University, UK
Queen Elizabeth Hospital, Gateshead, UK

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Jean-Louis Wemeau Clinique Endocrinologique Marc-Linquette, CHU, Lille, France

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, et al: The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol 1995;43:55-68. 10.1111/j.1365-2265.1995.tb01894.x 7641412 4 Surks MI, Hollowell JG: Age-specific distribution of serum

Article Type:
Letter
DOI:
https://doi.org/10.1159/000360622
Volume/Issue:
Volume 3: Issue 2
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Jonah Robinson Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Max Richardson Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Janis Hickey British Thyroid Foundation, Harrogate, UK

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Andy James Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Simon H. Pearce Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Steve G. Ball Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Richard Quinton Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Margaret Morris Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Margaret Miller Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Petros Perros Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK

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Introduction Hyperthyroidism affects approximately 1% of the adult population [ 1 , 2 ]. Antithyroid drugs are commonly used to control hyperthyroidism [ 3 , 4 ]. Assuming an incidence of Graves' disease in Europe of 21/100,000 per year [ 5

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367990
Volume/Issue:
Volume 3: Issue 4
Free access
Mikael Nilsson University of Gothenburg, Göteborg, Sweden

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E. Dillwyn Williams University of Cambridge, Cambridge, UK

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origins of the organs involved. Good examples include Lynch syndrome where a mutated DNA repair gene is associated with an increased incidence of colon, endometrial, ovarian and other cancers, and Li Fraumeni syndrome where germline mutations in p53 are

Article Type:
Letter
DOI:
https://doi.org/10.1159/000450680
Volume/Issue:
Volume 5: Issue 4
Free access
Constance Xhaard U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Juan J. Lence-Anta National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Yan Ren U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Françoise Borson-Chazot Groupement Hospitalier Lyon-Est, Hospices Civils de Lyon, Fédération d'Endocrinologie, Bron
Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon

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Geneviève Sassolas Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon

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Claire Schvartz Thyroid Cancer Registry of Champagne-Ardennes, Institut Jean Godinot, Reims

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Marc Colonna Cancer Registry of Isère, Meylan

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Brigitte Lacour Institut Gustave Roussy, Villejuif, France
French National Registry of Childhood Solid Tumours, CHU, Nancy

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Arlette Danzon Cancer Registry of Doubs, EA 3181, Université de Franche-Comté, Besançon

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Michel Velten Cancer Registry of Bas-Rhin, EA 3430, Faculty of Medicine, University of Strasbourg, Strasbourg

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Enora Clero U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Stéphane Maillard U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Emilie Marrer Cancer Registry of Haut-Rhin, Mulhouse Hospital, Mulhouse

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Laurent Bailly Public Health Department, University Hospital Nice, Nice

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Eugènia Mariné Barjoan Public Health Department, University Hospital Nice, Nice

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Martin Schlumberger Institut Gustave Roussy, Villejuif, France

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Jacques Orgiazzi Department of Endocrinology, Hospices Civils de Lyon, Lyon, France

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Elisabeth Adjadj U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Université Paris-Saclay, Villejuif, France

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Celia M. Pereda National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Silvia Turcios National Institute of Endocrinology, Cuba

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Milagros Velasco National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Mae Chappe National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Idalmis Infante National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Marlene Bustillo National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Anabel García National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Sirced Salazar National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Regla Rodriguez Cuban Public Health Ministry, Havana, Cuba

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Mohamed Amine Benadjaoud U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Rosa M. Ortiz National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Carole Rubino U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Florent de Vathaire U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Introduction Over the last few decades, the differentiated thyroid cancer (DTC) incidence has grown rapidly in many countries [ 1 ]. The study of DTC risk factors is therefore of great importance to understand this observed increase in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000445887
Volume/Issue:
Volume 5: Issue 2
Free access