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Giovanni Mauri Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, Denmark

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Steven Bandula Interventional Oncology Service, University College Hospital, London, United Kingdom

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Roberto Luigi Cazzato Department of Interventional Radiology, University Hospital of Strasbourg, Strasbourg, France

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Agnieszka Czarniecka The Oncologic and Reconstructive Surgery Clinic, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

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Oliver Dudeck Center for Microtherapy, Klinik Hirslanden, Zurich, Switzerland

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Laura Fugazzola Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Romana Netea-Maier Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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Gilles Russ Thyroid and Endocrine Tumors Unit, La Pitie-Salpetriere Hospital, Sorbonne University, Paris, France

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Göran Wallin Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

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Enrico Papini Department of Endocrinology & Metabolism, Ospedale Regina Apostolorum, Albano, Italy

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follow-up in about 1.4% of patients and most of them occurred within 8 years [ 3 ]. However, the risk of recurrence or persistent structural disease rapidly increases in patients with advanced stage at diagnosis. Disease persistence or relapse are

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Yaser Jbara Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA

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Dean Bricker Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA

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What Is Known about This Topic? • The coexistence of statin therapy and hypothyroid states may synergistically increase the risk of myopathy. What Does This Case Report Add? • There are a few previously reported cases of statin

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Silvia Turcios National Institute of Endocrinology, Cuba

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Juan J. Lence-Anta Institute of Oncology and Radiobiology, Cuba

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Jose-Luis Santana Institute of Oncology and Radiobiology, Cuba

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Celia M. Pereda Institute of Oncology and Radiobiology, Cuba

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Milagros Velasco Institute of Oncology and Radiobiology, Cuba

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Mae Chappe Institute of Oncology and Radiobiology, Cuba

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Idalmis Infante Cuban Health Public Ministry, Havana, Cuba

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Marlene Bustillo Institute of Oncology and Radiobiology, Cuba

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Anabel García Institute of Oncology and Radiobiology, Cuba

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Enora Clero Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Stephane Maillard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Regla Rodriguez Cuban Health Public Ministry, Havana, Cuba

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Constance Xhaard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Yan Ren Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Carole Rubino Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Rosa M. Ortiz Institute of Oncology and Radiobiology, Cuba

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Florent de Vathaire Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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and nonmedullary differentiated thyroid cancer (DTC) risk could be due to a common correlation with thyroid volume [ 3 ]. Anthropometric and clinical determinants of thyroid volume in adults [ 1 , 4 , 5 ] and children [ 6 , 7 , 8 ] have been

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Carla Gambale Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Alessandro Prete Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Chiara Romei Department of Diagnostic Imaging, Unit of Radiology, Pisa University Hospital, Pisa, Italy

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Alessandro Celi Department of Surgery, Medicine, Molecular Biology and Critical Care, Respiratory Pathophysiology Unit, Pisa University Hospital, Pisa, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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Antonio Matrone Department of Clinical and Experimental Medicine, Unit of Endocrinology, Pisa University Hospital, Pisa, Italy

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cases previously treated with immune checkpoint inhibitors (ICI) ( 24 ). Cases of OB are usually described in adult patients (median age is about 50 years old) and in the context of specific risk factors, such as following a lung transplant with

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Stine Linding Andersen Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Aarhus, Denmark

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Jørn Olsen Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark

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Chun Sen Wu Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark

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Peter Laurberg Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Aarhus, Denmark

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in case series [ 5 , 11 , 12 , 13 ]. In the present study, we aimed to evaluate the risk of early (spontaneous abortion) and late (stillbirth) pregnancy loss in women suffering from hyperthyroidism in a population-based design. Using Danish nationwide

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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia,” Udine

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Andrea Frasoldati Division of Endocrinology, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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). Fig. 2 Level of acceptance of the 2015 American Thyroid Association (ATA) guidelines (GL). US Risk Categories When asked about providing clinical data or US risk categories in US reports, 63.8% of respondents provided descriptive

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Ziyu Wan Health Management Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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Ying Li Health Management Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China

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Xiaoqian Dong Xiangya School of Nursing, Central South University, Changsha, Hunan, China

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Yue Kang Xiangya School of Nursing, Central South University, Changsha, Hunan, China

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Juan Luo Xiangya School of Nursing, Central South University, Changsha, Hunan, China

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Jiangang Wang Health Management Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China

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Pingting Yang Health Management Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China

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Yaqin Wang Health Management Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China

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Yinglong Duan Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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Jianfei Xie Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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Andy S K Cheng Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong, China

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help clinicians identify at-risk groups, leading to early detection and treatment of TNs. Several studies have reported a positive correlation between metabolic syndrome (MetS) and the risk of TNs ( 8 , 9 , 10 ). MetS is a pathological condition

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Ho-Ryun Won Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea

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Min Gyu Kim Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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Min Soo Kim Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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Jae Won Chang Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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Bon Seok Koo Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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management protocol given the indolent characteristics of PTMC ( 11 , 12 ). Patients with the following clinically high-risk characteristics are excluded from AS: (i) cases with lymphatic metastasis or distant metastasis, (ii) cases with symptoms

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J L Reverter Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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L Ferrer-Estopiñan Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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F Vázquez Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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S Ballesta Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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S Batule Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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A Perez-Montes de Oca Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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C Puig-Jové Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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M Puig-Domingo Endocrinology and Nutrition Service, Germans Trias i Pujol Hospital and Research Institute, Badalona, Spain
Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain

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nodules has enhanced the need for endocrinologists to be able to define the risk of malignancy as accurately as possible ( 2 ). Ultrasound (US) is the first-line method to identify malignant thyroid nodules with the advantages of accessibility, cost

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Irini S. Hadjisavva Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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Roberto Dina Department of Cellular Pathology, Hammersmith Hospital, Imperial College Healthcare Trust, London, UK

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Michael A. Talias Healthcare Management Postgraduate Program, Open University of Cyprus, Nicosia, Cyprus

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Panayiotis A. Economides Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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well as the presence of autoimmune thyroid disease were evaluated as potential risk factors. Patients and Methods 322 consecutively examined patients (272 female and 50 male), aged 13-81, were included in this study. These patients underwent

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