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Lei Xu Key Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China
Xi’an Hospital of Traditional Chinese Medicine, Xi’an, China

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Junling Gao Key Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China

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Quan Wang Laboratory of Surgical Oncology, Peking University People’s Hospital, Peking University, Beijing, China

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Jichao Yin Xi’an Hospital of Traditional Chinese Medicine, Xi’an, China

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Pengfei Yu Xijing Hospital, Fourth Military Medical University, Xi’an, China

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Bin Bai Xijing Hospital, Fourth Military Medical University, Xi’an, China

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Ruixia Pei Xi’an Hospital of Traditional Chinese Medicine, Xi’an, China

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Dingzhang Chen Xijing Hospital, Fourth Military Medical University, Xi’an, China

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Guochun Yang Xi’an Hospital of Traditional Chinese Medicine, Xi’an, China

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Shiqi Wang Xijing Hospital, Fourth Military Medical University, Xi’an, China

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Mingxi Wan Key Laboratory of Biomedical Information Engineering of the Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China

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participated in the assessment, only the most experienced one was selected for the analysis. Both pathological examination of the surgical specimen and cytological examination of fine needle aspiration tissue were considered acceptable reference standards. A

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Evangelos Karvounis Department of Endocrine Surgery Center of Excellence, Euroclinic Hospital, Athens, Greece

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Ioannis Kappas Department of Endocrine Surgery Center of Excellence, Euroclinic Hospital, Athens, Greece

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Anna Angelousi First Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece

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Georgios-Marios Makris Department of Gynecology, Euroclinic Hospital, Athens, Greece

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Eva Kassi First Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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histopathological diagnosis of MALT lymphoma in the included studies, ranging from fine needle aspiration to thyroidectomy (subtotal or total). They specifically mentioned that the specimen that is obtained by means of fine needle aspiration is too small to reach

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Lucie Allard Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Jérôme Alexandre Denis Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Biochimie Endocrinienne et Oncologique, UF Oncobiologie Cellulaire et Moléculaire, Pitié Salpêtrière, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Gaëlle Godiris Petit Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Chirurgie Générale, Viscérale et Endocrinienne, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Gabrielle Deniziaut Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service d’Anatomo-Pathologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Cécile Ghander Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Elise Mathy Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Erell Guillerm Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, UF d’Onco-Angiogénétique et Génomique des Tumeurs Solides, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Charlotte Lussey-Lepoutre Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Médecine Nucléaire, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Laurence Leenhardt Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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Camille Buffet Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France

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, there were neither poorly nor undifferentiated components observed. B-Raf c.1799T>A (p.Val600Glu) ( BRAF V600E ) and telomerase reverse transcriptase C228T ( TERT C228T ) promoter mutations, identified on fine-needle aspiration (washed-out solution), are

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Furio Pacini Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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literature and expert opinion, the Guidelines come out with several recommendations dealing with standardization of the US scanning procedure, techniques and indications for US-guided fine-needle aspiration (US-FNA), classification of malignancy risk based on

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Rémy Louvel Head and Neck Surgical Oncology Department, Institut Curie, PSL University, Paris, France

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Nathalie Badois Head and Neck Surgical Oncology Department, Institut Curie, PSL University, Paris, France

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Jerzy Klijanienko Pathology Department, Institut Curie, PSL University, Paris, France

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Ségolène Hescot Medical Oncology Department, Institut Curie, PSL University, Paris, France

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Caroline Hoffmann Head and Neck Surgical Oncology Department, Institut Curie, PSL University, Paris, France

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years earlier by robot-assisted transaxillary surgery (RATS). Benign colloid and thyroid cells were found in two successive fine needle aspirations. The CT scan revealed an ill-defined infiltrative lesion in the right central compartment with muscle and

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Jan Jiskra 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jiří Horáček 4th Department of Medicine, Faculty of Medicine, Charles University, University Hospital Hradec Králové, Czech Republic

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Sylvie Špitálníková Department of Nuclear Medicine, District Hospital, Havlíčkův Brod, Czech Republic

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Jan Paleček 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Zdeňka Límanová 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jan Krátký 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Drahomíra Springer Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Kristýna Žabková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Hana Vítková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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, and/or (iii) any assisted reproduction technique used. GDM was defined as a medical record about its presence during a previous and/or current pregnancy. Thyroid ultrasound and fine-needle aspiration cytology In women included in the study, one

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Pi-Ling Chiang Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Sheng-Dean Luo Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yen-Hsiang Chang Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Chen-Kai Chou Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Shun-Yu Chi Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yi-Fan Chen Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Wei-Che Lin Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan

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practice, thyroid nodules are being discovered with increasing frequency. Thyroid fine needle aspiration cytology (FNAC) is the most accurate test for determining malignancy and is an integral part of current thyroid nodule evaluation procedures ( 2

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Simona Censi Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Elisabetta Cavedon Familial Tumor Unit, Veneto Institute of Oncology, (IOV)-IRCCS, Padua, Italy

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Sara Watutantrige-Fernando Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Susi Barollo Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Loris Bertazza Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Jacopo Manso Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Maurizio Iacobone Surgery Unit, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University of Padua, Padua, Italy

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Davide Nacamulli Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Francesca Galuppini Surgical Pathology & Cytopathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Gianmaria Pennelli Surgical Pathology & Cytopathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Caterina Mian Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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uptake, neither in the thyroid node. The patient underwent fine-needle aspiration biopsy of the mammary node, and cytology was suggestive of breast cancer cells. Ctn levels in the washout fluid from the fine-needle aspiration were 27 ng/L. We concluded

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Satoshi Koyama Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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Naritomo Miyake Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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Kazunori Fujiwara Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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Tsuyoshi Morisaki Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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Takahiro Fukuhara Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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Hiroya Kitano Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan
Center for Head and Neck Surgery, Kusatsu General Hospital, Kusatsu, Japan

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Hiromi Takeuchi Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan

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aspiration cytology. Liquid-based cytology and cell block cytology techniques were combined with the conventional technique. Only case 5 was histologically diagnosed using lymph node biopsy because of insufficient information from fine-needle aspiration

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Amruth R. Palla Division of Hematology and Oncology, Department of Internal Medicine, Ellis Fischel Cancer Center, University of Missouri Columbia, Columbia, Missouri, USA

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Craig Allen Bollig Department of Otolaryngology – Head and Neck Surgery, Ellis Fischel Cancer Center, University of Missouri Columbia, Columbia, Missouri, USA

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Jeffrey Brian Jorgensen Department of Otolaryngology – Head and Neck Surgery, Ellis Fischel Cancer Center, University of Missouri Columbia, Columbia, Missouri, USA

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visualized and appeared patent. A fine needle aspiration biopsy of the left neck mass was performed and the cytology was negative for malignant cells. Despite benign cytopathology and a relative lack of symptoms, a left thyroid lobectomy was offered to the

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