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F. Cecoli Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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E.M. Ceresola Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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V. Altrinetti Endocrinology and Nuclear Medicine, Galliera Hospital, Genoa

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M. Cabria Endocrinology and Nuclear Medicine, Galliera Hospital, Genoa

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M. Cappagli Endocrine Unit, Sant'Andrea Hospital, La Spezia

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A. Montepagani Endocrine Unit, Sant'Andrea Hospital, La Spezia

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C.M. Cuttica Endocrinology and Nuclear Medicine, Galliera Hospital, Genoa

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U. Filippi Evangelico Internazionale Hospital, Genoa

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D. Saverino Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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M. Raffa Endocrine-Metabolic Center, ASL 1, Imperia, Italy

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M. Caputo Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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F. Minuto Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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M. Giusti Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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M. Bagnasco Endocrinology, Nuclear Medicine and Autoimmunity Laboratory, Department of Internal Medicine, and Department of Experimental Medicine, Genoa University, and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Genoa

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14 Sugitani I, Fujimoto Y: Management of low-risk papillary thyroid carcinoma: unique conventional policy in Japan and our efforts to improve the level of evidence. Surg Today 2010;40:199-215. 10.1007/s00595-009-4034-5 20180072 15 Sugitani I

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000446746
Volume/Issue:
Volume 5: Issue 3
Free access
Ho-Ryun Won Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea

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Min Gyu Kim Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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Min Soo Kim Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea

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Jae Won Chang Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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Bon Seok Koo Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea
Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea

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among all cancers ( 1 ). The majority of thyroid cancers are differentiated thyroid carcinoma, the most common form of which is papillary thyroid carcinoma ( 2 , 3 ). Since the 1980s, thyroid cancer, particularly papillary thyroid cancer, has been

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0195
Volume/Issue:
Volume 12: Issue 6
Open access
Irini S. Hadjisavva Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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Roberto Dina Department of Cellular Pathology, Hammersmith Hospital, Imperial College Healthcare Trust, London, UK

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Michael A. Talias Healthcare Management Postgraduate Program, Open University of Cyprus, Nicosia, Cyprus

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Panayiotis A. Economides Economides Nicosia Endocrinology Center, Nicosia, Cyprus

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estimated mortality rate of 5,993 patients each year [ 12 ]. Studies have shown a true rise in the incidence of micro and larger forms of papillary thyroid carcinoma in northwestern Spain, a higher incidence of thyroid cancer in the volcanic area of Sicily

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000430438
Volume/Issue:
Volume 4: Issue 2
Free access
Junyu Tong Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Maomei Ruan Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
Department of Nuclear Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China

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Yuchen Jin Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Hao Fu Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Lin Cheng Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Qiong Luo Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China

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Zhiyan Liu Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Zhongwei Lv Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China

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Libo Chen Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China

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Introduction The incidence of thyroid cancer, the most common endocrine malignancy, has been increasing over the past decades. More than 87% of thyroid cancers are distinguished as differentiated thyroid carcinoma (DTC), including papillary

Article Type:
Review Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-22-0021
Volume/Issue:
Volume 11: Issue 2
Open access
Johannes Järhult Department of Surgery, Highland Hospital, Eksjö, Sweden
Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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Ramtin Vedad Department of Surgery, County Hospital Ryhov, Jönköping, Sweden

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malignancy (of whom 5 had carcinomas). Six patients had thyroid surgery due to thyrotoxicosis. Table 2 Main indication for thyroid surgery at re-referral in 102 patients with benign non-toxic goitre managed with expectancy at first visit

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367845
Volume/Issue:
Volume 3: Issue 4
Free access
Hyunju Park Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea

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Jung Heo Division of Endocrinology and Metabolism, Department of Internal Medicine, Myongji Hospital, Hanyang University College of Medicine, Goyang-si, Gyeonggi-do, Korea

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Hyun Jin Ryu Division of Endocrinology & Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Min-Ji Kim Statistics and Data Center, Samsung Medical Center, Research Institute for Future Medicine

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Young Lyun Oh Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Tae Hyuk Kim Division of Endocrinology & Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Sun Wook Kim Division of Endocrinology & Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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Jae Hoon Chung Division of Endocrinology & Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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. Additionally, the prevalence of the BRAFV600E mutation in papillary thyroid carcinoma (PTC) ranges from 30% to greater than 80% ( 16 , 17 ), varying by geographic region and dietary components such as iodine intake ( 18 ). Thus, we conducted this study to

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0255
Volume/Issue:
Volume 13: Issue 5
Open access
Chitra Choudhary Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Leonard Wartofsky Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Eshetu Tefera MedStar Health Research Institute, Washington, D.C., USA

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Kenneth D. Burman Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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clinically significant structural progression. Thyroid 2011;21:845-853. 10.1089/thy.2011.0011 21809914 7 Grant CS, Hay ID, Gough IR, Bergstralh EJ, Goellner JR, McConahey WM: Local recurrence in papillary thyroid carcinoma: is extent of surgical

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000431317
Volume/Issue:
Volume 4: Issue 2
Free access
Mohammad-Reza Mahmoudian-sani Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Department of Genetics and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

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Ameneh Mehri-Ghahfarrokhi Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

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Majid Asadi-Samani Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran

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Gholam-Reza Mobini Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

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are involved in apoptosis and cell cycle regulation. Targeting this subset of miRNAs can be useful in thyroid papillary carcinoma diagnosis and treatment management [ 28 ]. miRNA-375 Two separate studies examined the expression status of miRNA

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000468520
Volume/Issue:
Volume 6: Issue 4
Free access
Min Ji Jeon Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Gu Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Ki-Wook Chung Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Jung Hwan Baek Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Bae Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Young Kee Shong Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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carcinomas (PTCs) including papillary thyroid microcarcinomas (PTMCs) [ 1 , 2 ]. For the last several decades, we did not have sufficient knowledge of the biological behavior of PTMCs, and were surprised to find that many of these PTMCs have similar

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000503064
Volume/Issue:
Volume 8: Issue 6
Free access
Mario Monaco Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Gennaro Chiappetta Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Concetta Aiello Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Antonella Federico Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Romina Sepe Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Daniela Russo Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Alfredo Fusco Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy
Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil

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Pierlorenzo Pallante Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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thyroid neoplasias [ 4 ]. Indeed, its expression is slightly reduced in papillary and follicular carcinomas compared to normal thyroid tissues, whereas its expression is not detected at all in anaplastic thyroid carcinomas. Re-expression of CBX7 in thyroid

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367989
Volume/Issue:
Volume 3: Issue 4
Free access