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  • thyroglobulin x
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Anthony P. Weetman Department of Human Metabolism, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK

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, when the studies of Rose and Witebsky [ 9 ]first convincingly showed that rabbits immunized with thyroglobulin produced autoantibodies to this self-protein, accompanied by lymphocytic thyroiditis. (Incidentally, this was not the first description of

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000343834
Volume/Issue:
Volume 1: Issue 4
Free access
Furio Pacini Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy

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131 I. The aim of postsurgical ablation of the thyroid remnant with RAI is to facilitate the early detection of recurrence based on serum thyroglobulin (Tg) measurement and RAI whole body scan. In addition, RAI ablation may represent an adjuvant

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000442880
Volume/Issue:
Volume 5: Issue 1
Free access
Cosimo Rodia Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Francesca Menconi Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Laura Mazoni Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Liborio Torregrossa Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Michele Marinò Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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abundance within the thyroid and its solubility, the most suitable candidate was thyroglobulin (Tg), and a few studies showed its presence in orbital tissues from GO patients, although no pathogenetic role of Tg was demonstrated [ 6 , 8 , 9

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000500297
Volume/Issue:
Volume 8: Issue 5
Free access
Mitsuaki Tokumaru Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan

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Kenji Ohba Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Kennichi Kakudo Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Izumi, Japan

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Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Yutaka Oki Department of Family and Community Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Yoshie Goto Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan

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hospital visit. Palpation revealed a painless, firm, 2.5 × 2.0-cm nodule on the right side of her neck. Thyroid function tests revealed a euthyroid status. Anti-thyroglobulin and anti-thyroperoxidase antibodies levels were high (1,490 IU/mL [reference range

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000507826
Volume/Issue:
Volume 10: Issue 5
Free access
Denise P. Carvalho Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Corinne Dupuy Université Paris-Sud, UMR 8200 CNRS, Institute Gustave Roussy, Villejuif, France

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called thyroglobulin, and they remain covalently bound to the primary structure of this molecule until protein degradation occurs and the hormone is secreted. The first step in thyroid hormone biosynthesis corresponds to the iodination of tyrosyl residues

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000354745
Volume/Issue:
Volume 2: Issue 3
Free access
Matthieu Bosset Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Maxime Bonjour Service de Biostatistique, Hospices Civils de Lyon, Lyon, France

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Solène Castellnou Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Zakia Hafdi-Nejjari Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Claire Bournaud-Salinas Centre de Médecine Nucléaire, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Myriam Decaussin-Petrucci Service d’Anatomie-Pathologique, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France

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Jean Christophe Lifante Service de Chirurgie Endocrinienne, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France
Laboratoire Health Services and Performance Research (EA 7425 HESPER), Université Claude Bernard Lyon 1, Villeurbanne, France

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Agnès Perrin Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Jean-Louis Peix Service de Chirurgie Endocrinienne, Hospices Civils de Lyon, Groupement Hospitalier Lyon-Sud, Pierre Bénite, France

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Philippe Moulin Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
CarMeN Laboratory, Université Claude-Bernard Lyon 1, Inserm U1060, INRA U1397, INSA Lyon, IMBL, Villeurbanne, France

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Geneviève Sassolas Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Michel Pugeat Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France

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Françoise Borson-Chazot Fédération d’Endocrinologie, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
Registre des Cancers Thyroïdiens du Département du Rhône, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
Laboratoire Health Services and Performance Research (EA 7425 HESPER), Université Claude Bernard Lyon 1, Villeurbanne, France

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study period were to be followed at least each year following surgery by clinical examination and laboratory tests. Monitoring procedures changed over the study period and thyroglobulin was to be measured regularly since 1990. Ultrasounds were initially

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000510620
Volume/Issue:
Volume 10: Issue 6
Free access
Pedro Weslley Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Gabriela Franco Mourão Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Maria Regina Calsolari Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Chemiluminescent assays were used for the measurement of Tg (Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA, USA [functional sensitivity (FS) in our laboratory of 0.1 ng/ml]) and TgAb (Immulite 2000, Diagnostic Products Corporation, Los Angeles, CA, USA

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000493978
Volume/Issue:
Volume 8: Issue 1
Free access
Kaoru Kobayashi Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuyoshi Hirokawa Kuma Hospital, Kobe City, Hyogo, Japan

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Tomonori Yabuta Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuhiro Fukushima Kuma Hospital, Kobe City, Hyogo, Japan

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Minoru Kihara Kuma Hospital, Kobe City, Hyogo, Japan

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Yuuki Takamura Kuma Hospital, Kobe City, Hyogo, Japan

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Yasuhiro Ito Kuma Hospital, Kobe City, Hyogo, Japan

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Akihiro Miya Kuma Hospital, Kobe City, Hyogo, Japan

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Nobuyuki Amino Kuma Hospital, Kobe City, Hyogo, Japan

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Akira Miyauchi Kuma Hospital, Kobe City, Hyogo, Japan

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histopathological findings. All the patients presented negative anti-thyroglobulin antibody in serum, well-differentiated type of papillary thyroid carcinoma and lymph node metastasis on histopathology. Cervical lymph nodes swelling indicating metastasis were

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000353780
Volume/Issue:
Volume 2: Issue 4
Free access
Martina Tavarelli Unité Thyroïde Tumeurs Endocrines, Paris, France

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Julie Sarfati Unité Thyroïde Tumeurs Endocrines, Paris, France

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Christian De Gennes Service de Médecine Interne Immuno-clinique, Paris, France

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Julien Haroche Service de Médecine Interne 2, Paris, France

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Camille Buffet Unité Thyroïde Tumeurs Endocrines, Paris, France

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Cécile Ghander Unité Thyroïde Tumeurs Endocrines, Paris, France

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Jean Marc Simon Service de Radiothérapie, Paris, France

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Fabrice Ménégaux Service de Chirurgie Générale et Digestive, Groupe Hospitalier et Faculté de Médecine Pitié-Salpêtrière, Institut du Cancer, Université Pierre et Marie Curie, Paris, France

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Laurence Leenhardt Unité Thyroïde Tumeurs Endocrines, Paris, France

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follicular well-differentiated cancer classified as pT3NxMx. Subsequently, radioiodine therapy with 100 mCi 131 I after LT4 withdrawal was performed in October 2007, showing an intense unique cervical fixation with no distant metastases. The thyroglobulin

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000437052
Volume/Issue:
Volume 4: Issue 4
Free access
Ringo Manta Department of Nuclear Medicine, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Charlotte Martin Department of Infectious Diseases, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Vinciane Muls Department of Gastroenterology and Endoscopy, CHU Saint-Pierre, University Libre de Bruxelles (ULB), Brussels, Belgium

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Kris G Poppe Department of Endocrinology, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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late April, showing elevated levels of TRAb and thyroglobulin with normal levels of antithyroglobulin antibodies. Laboratory test results are shown in Table 1 . Table 1 Laboratory test results of the patient. Laboratory analysis

Article Type:
Case Report
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0049
Volume/Issue:
Volume 11: Issue 4
Open access