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Bengt Hallengren Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Tereza Planck Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Peter Åsman Departments of Ophthalmology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Mikael Lantz Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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grandmother had thyrotoxicosis, developed SAT in March 1998. The diagnosis was verified by fine-needle aspiration with cytological examination (fig. 1 ). She was given glucocorticoids and needed these for 1 year. In September 1998, her serum TSH level was

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Mitsuaki Tokumaru Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan

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Kenji Ohba Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Kennichi Kakudo Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Izumi, Japan

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Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Yutaka Oki Department of Family and Community Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

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Yoshie Goto Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan

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border was well defined, and its margin showed a broccoli-like growth pattern. Based on US findings (Fig.  1 a, b), we initially suspected thyroid lymphoma [ 5 ]; however, fine-needle aspiration cytology (FNAC) findings revealed the benign cytological

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C. Mari Aparici Nuclear Medicine, Radiology Department, University of California San Francisco, UCSF
Nuclear Medicine, Radiology Department, San Francisco VA Medical Center, San Francisco, Calif., USA

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T. Liu Nuclear Medicine, Radiology Department, University of California San Francisco, UCSF

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X-ray was suspicious for pulmonary nodules and this was confirmed by dedicated CT imaging of the chest, which also demonstrated a multinodular goiter. Thyroid ultrasound showed multiple nodules and a fine-needle aspiration of one of the dominant

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Pi-Ling Chiang Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Sheng-Dean Luo Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yen-Hsiang Chang Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Chen-Kai Chou Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Shun-Yu Chi Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yi-Fan Chen Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Wei-Che Lin Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan

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practice, thyroid nodules are being discovered with increasing frequency. Thyroid fine needle aspiration cytology (FNAC) is the most accurate test for determining malignancy and is an integral part of current thyroid nodule evaluation procedures ( 2

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Kristine Z Swan Department of ORL, Head- and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark

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Johnson Thomas Department of Endocrinology, Mercy Hospital, Springfield, Missouri, USA

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Viveque E Nielsen Department of ORL, Head- and Neck Surgery, Odense University Hospital, Odense, Denmark

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Marie Louise Jespersen Department of Pathology, Aarhus University Hospital, Aarhus, Denmark

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Steen J Bonnema Department of Endocrinology, Odense University Hospital, Odense, Denmark

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patients underwent fine-needle aspiration of the nodule. Bethesda categories (I–VI) were used to describe the cytopathological diagnosis ( 15 ). A histologically verified diagnosis, according to the WHO classification ( 16 ), was obtained in all patients

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Julia A Baran Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Mya Bojarsky Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Stephen Halada Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Julio C Ricarte-Filho Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Amber Isaza Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Aime T Franco Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Lea F Surrey Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Tricia Bhatti Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Zubair Baloch Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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N Scott Adzick Department of Surgery, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Sogol Mostoufi-Moab Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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Ken Kazahaya Division of Pediatric Otolaryngology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Andrew J Bauer Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

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cancer’ ( 13 ). Pre-operative assessment for surgical stratification commonly includes ultrasound (US) and fine needle aspiration (FNA), but these are highly subjective measures with wide variability in completeness and interpretation across

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Fahim U. Hassan Nuclear Medicine Department, Borough Wing, Guy's Hospital, London, UK

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Hosahalli K. Mohan Nuclear Medicine Department, Borough Wing, Guy's Hospital, London, UK

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the assessment of thyroid nodules. This, combined with fine-needle aspiration, is helpful in pre-surgical assessment of thyroid nodules and neck lymph nodes and post-surgery in the assessment for recurrent thyroid cancer in these patients. The

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Shi Hui Junice Wong Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore

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bilateral tender lymphadenopathy, worse on the left. Oral cavity and nasoendoscopy examination were unremarkable. Fine-needle aspiration of the left cervical lymph node showed a predominantly neutrophilic infiltrate compatible with acute inflammation

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Darshan Patil Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Abhay Kumaraswamy Kattepur Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Srinivas Kodaganur Gopinath Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Shivanand Swamy Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Amarendra Shankarappa Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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Gopinath Kodaganur Srinivasachar Department of Surgical Oncology, HCG-Bangalore Institute of Oncology, Bangalore, India

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in both the lobes. She was clinically euthyroid. X-ray of the left digit showed multiple lytic lesions in the terminal phalanx. Fine-needle aspiration cytology (FNAC) of the thyroid revealed follicular carcinoma. Biopsy from the growth in the little

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Laura Agate Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Francesca Bianchi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Federica Brozzi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Pierina Santini Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Eleonora Molinaro Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Valeria Bottici Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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David Viola Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Loredana Lorusso Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Paolo Vitti Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Rossella Elisei Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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supraclavear node compartments were evaluated for the presence of suspicious disease recurrence or persistence. In suspicious lymph node metastases, a fine-needle aspiration biopsy with Tg measurement in the needle washout was performed. 131 I

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