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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia,” Udine

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Andrea Frasoldati Division of Endocrinology, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Benign Nodule For a 25-year-old patient with a nodular goiter, benign FNA, and no compressive symptoms, 54.7% suggest iodized salt, 24.4% levothyroxine treatment aiming at a low-normal thyroid-stimulating hormone, and 18.6% advise avoidance of iodine

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000453032
Volume/Issue:
Volume 6: Issue 2
Free access
Roberto Negro Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Roberto Attanasio Endocrine Unit, IRCCS Istituto Galeazzi, Milan, Italy

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Enrico Papini Department of Endocrinology and Metabolism, Ospedale Regina Apostolorum, Rome, Italy

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Kristian H. Winther Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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a number of individual specific environmental variables, iodine intake and tobacco smoking being those most studied, accounts for the final phenotype most likely unique to any individual [ 2 , 3 ]. The disease has negative socioeconomic consequences

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000494837
Volume/Issue:
Volume 8: Issue 1
Free access
Signe Buhl Gram Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jacob Høygaard Rasmussen Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Jens Bentzen Department of Oncology, Herlev Hospital, Copenhagen University, Copenhagen, Denmark

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Giedrius Lelkaitis Department of Pathology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christian von Buchwald Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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Christoffer Holst Hahn Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

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preoperative cancer diagnosis. Our aims were (1) to report the risk of malignancy in cases referred for surgery either with benign FNA or without FNA and identify possible predictive risk factors of malignancy in a population with recent moderately low iodine

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000500539
Volume/Issue:
Volume 8: Issue 5
Free access
Roberto Negro Division of Endocrinology, ‘V. Fazzi' Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria ‘S. Maria della Misericordia', Udine

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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requested by 92.1%, while 1/4 of the respondents would order a thyroid scan (technetium-99) and only a minority would use radioactive iodine uptake (RAIU; 131 I) (fig. 2 a). Fig. 2 Rates of functional and anatomic investigations requested in the

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000444482
Volume/Issue:
Volume 5: Issue 2
Free access
Emilie Brûlé Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada

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Xiang Zhou Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada

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Ying Wang Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada

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Evan R S Buddle Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada

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Luisina Ongaro Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada

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Mary Loka Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada

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Anita Boelen Endocrine Laboratory, Department of Laboratory Medicine, University of Amsterdam, Amsterdam Gastroenterology, Endocrinology & Metabolism Research Institute, Amsterdam, The Netherlands

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Daniel J Bernard Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada
Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada

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’ responses to diet-induced hypothyroidism (e.g. chow low in iodine and supplemented with propylthiouracil) were not examined. From our experience with Igsf1 knockout mice, this challenge may be needed to reveal robust impairments in TSH synthesis and

Article Type:
Research Article
Collections:
Hypothalamus-pituitary-thyroid axis
DOI:
https://doi.org/10.1530/ETJ-23-0054
Volume/Issue:
Volume 13: Issue 1
Open access
Hirotoshi Nakamura Kuma Hospital, Kobe, Japan

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Akane Ide Kuma Hospital, Kobe, Japan

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Takumi Kudo Kuma Hospital, Kobe, Japan

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Eijun Nishihara Kuma Hospital, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Kobe, Japan

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operation; KI = inorganic iodine (38 mg iodine daily); another ATD = change to MMI from PTU. * The OP patient died suddenly at home from an unknown cause just a few days before the scheduled total thyroidectomy. The remaining 9 AG patients (36

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000448586
Volume/Issue:
Volume 5: Issue 4
Open access
Meihua Jin Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine and School of Medicine, Seoul, Republic of Korea

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Ahreum Jang Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Division of Endocrinology and Metabolism, Department Internal Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea

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Chae A Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Tae Yong Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Bae Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Young Kee Shong Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Min Ji Jeon Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Gu Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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gland ( 1 , 2 ). Current treatment options for patients with Graves’ hyperthyroidism include antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, and surgery ( 1 , 3 , 4 ). Although geographical difference exists, ATD is the preferred first

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0226
Volume/Issue:
Volume 12: Issue 2
Open access
Rony Ruben Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Praveen V. Pavithran Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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V. Usha Menon Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Vasantha Nair Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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Harish Kumar Department of Endocrinology, Amrita Institute of Medical Sciences, Kochi, India

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total thyroidectomy and radioactive iodine ablation at the Thyroid Cancer Clinic of our Institute and to assess which of these most accurately predicted outcomes using clinical end points. The secondary objective was to compare the performance of the

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000500773
Volume/Issue:
Volume 8: Issue 6
Free access
Ladan Mehran Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Atieh Amouzegar Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Hengameh Abdi Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Negar Delbari Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Elham Madreseh Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

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Maryam Tohidi Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Mohammad Ali Mansournia Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

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Fereidoun Azizi Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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individuals with and without MetS as well as evaluating the incidence of TD and trend of thyroid hormones according to the MetS group, during a 10 year follow-up in an iodine sufficient population. Materials and Methods Study Design TTS is a

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1159/000512665
Volume/Issue:
Volume 10: Issue 5
Free access
Cosimo Rodia Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Francesca Menconi Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Laura Mazoni Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Liborio Torregrossa Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Michele Marinò Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Graves’ hyperthyroidism since 1988, for which he had been treated with methimazole for 8 years, and then with radioactive iodine (in 1996), with consequent hypothyroidism, for which he was on L-thyroxine 150 µg/day. He reported the appearance of bilateral

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000500297
Volume/Issue:
Volume 8: Issue 5
Free access