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Cláudia C.D. Nakabashi Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Teresa S. Kasamatsu Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Felipe Crispim Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Claudia A. Yamazaki Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Cléber P. Camacho Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Danielle M. Andreoni Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Rosalia P. Padovani Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Elza S. Ikejiri Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Maria C.O.M. Mamone Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Flávia C. Aldighieri Fleury Medicina e Saúde, São Paulo, Brazil

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Jairo Wagner Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Jairo T. Hidal Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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José G.H. Vieira Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicina e Saúde, São Paulo, Brazil

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Rosa P.M. Biscolla Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Rui M.B. Maciel Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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modalities used to monitor patients for residual or recurrent disease. Tg has high sensitivity and specificity in detecting thyroid cancer, especially after total thyroidectomy and remnant ablation, with the highest sensitivity noted after thyroid hormone

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Akira Miyauchi Departments of Surgery, Kuma Hospital, Kobe, Japan

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Takumi Kudo Departments of Internal Medicine, Kuma Hospital, Kobe, Japan

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Mitsuyoshi Hirokawa Departments of Pathology, Kuma Hospital, Kobe, Japan

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Yasuhiro Ito Departments of Surgery, Kuma Hospital, Kobe, Japan

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Minoru Kihara Departments of Surgery, Kuma Hospital, Kobe, Japan

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Takuya Higashiyama Departments of Surgery, Kuma Hospital, Kobe, Japan

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Tomonori Yabuta Departments of Surgery, Kuma Hospital, Kobe, Japan

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Hiroo Masuoka Departments of Surgery, Kuma Hospital, Kobe, Japan

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Hisakazu Shindo Departments of Surgery, Kuma Hospital, Kobe, Japan

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Kaoru Kobayashi Departments of Surgery, Kuma Hospital, Kobe, Japan

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Akihiro Miya Departments of Surgery, Kuma Hospital, Kobe, Japan

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in patients with papillary carcinoma and undetectable Tg antibody (TgAb) who underwent total thyroidectomy, when Tg-DT was calculated using serum Tg values measured under thyrotropin (TSH)-suppressed conditions [ 6 ]. Ki-67 is a cell proliferation

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Rosa M. García-Moreno Endocrinology and Nutrition Department, Hospital Universitario La Paz, Madrid, Spain

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Cristina Escabias Nuclear Medicine Department, Hospital Universitario La Paz, Madrid, Spain

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Cristina Utrilla Radiology Department, Hospital Universitario La Paz, Madrid, Spain

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Elena Ruiz-Bravo Pathology Department, Hospital Universitario La Paz, Madrid, Spain

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Margarita Sánchez Ophthalmology Department, Hospital Universitario La Paz, Madrid, Spain

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Beatriz Lecumberri Endocrinology and Nutrition Department, Hospital Universitario La Paz, Madrid, Spain

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PTC might also be misleadingly attributed to the presence of true distant metastases [ 2 ]. Case Report We report the case of a 62-year-old female with a history of PTC (follicular variant) treated with total thyroidectomy in 1998. She received

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María de los Ángeles Garayalde Gamboa Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Melina Saban Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Marina Ines Curriá Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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intestinal subocclusion treated in the first instance with enterectomy and then with gastric repose on several subsequent occasions. In December 2014, a total thyroidectomy was performed due to a follicular-variant papillary carcinoma. He received treatment

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Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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clinical findings and the suspicious cytological result, the patient underwent a total thyroidectomy. As a result of the fibrotic extensions to the perithyroidal soft tissues, dissection of thyroid gland proved difficult during surgery. The surgical

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Jorge Alberto Tapia-Martínez Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México
Laboratorio 6, Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados-Instituto Politécnico Nacional, Delegación Tlalpan, Ciudad de México, México

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Margarita Franco-Colín Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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Vanessa Blas-Valdivia Laboratorio de Neurobiología, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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Edgar Cano-Europa Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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°C) and maintained with food and water ad libitum. After a week of conditioning, animals were randomly divided into two mothers groups ( n = 9): (i) euthyroid and (ii) hypothyroid. Hypothyroidism was induced surgically by a thyroidectomy with

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Birte Nygaard Departments of Endocrinology, Herlev University Hospital, Herlev

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Lars Bastholt Department of Oncology, Odense University Hospital, Odense, Denmark

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Finn Noe Bennedbæk Departments of Endocrinology, Herlev University Hospital, Herlev

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Tobias Wirenfeldt Klausen Departments of Haematology, Herlev University Hospital, Herlev

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Jens Bentzen Departments of Oncology, Herlev University Hospital, Herlev

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measurement. Materials and Methods Patients Consecutive patients with DTC treated by total thyroidectomy and indication of postsurgery RI ablation therapy were included in the study. Patients with age <18 or >75 years, as well as patients not

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Massimo Giusti Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy
Department of Internal Medicine, University of Genoa, Genoa, Italy

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Stefano Gay Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy
Department of Internal Medicine, University of Genoa, Genoa, Italy

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Lucia Conte Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy
Department of Internal Medicine, University of Genoa, Genoa, Italy

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Francesca Cecoli Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy

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Lorenzo Mortara Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy

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Lara Vera Endocrine Unit, San Martino Polyclinic Hospital, Genoa, Italy

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Eleonora Monti Department of Internal Medicine, University of Genoa, Genoa, Italy

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concerned with physical appearance. Choi et al. [ 33 ] evaluated QoL in 97 patients using the Dermatology Life Quality Index. They found that scores did not differ among scar types, but that post-thyroidectomy scars on the neck did influence the life of

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Inês Damásio Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Joana Simões-Pereira Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Sara Donato Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Nova Medical School, Lisbon, Portugal

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Mariana Horta Radiology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon Portugal

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Branca Maria Cavaco Molecular Pathobiology Research Unit (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Miguel Rito Pathology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Pedro Gomes Head and Neck Surgery Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Nova Medical School, Lisbon, Portugal

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( Fig. 1D ). At this point, ATC was considered surgically resectable, and the patient underwent total thyroidectomy plus central lymphadenectomy. Histological analysis ( Fig. 2B and C ) revealed the presence of residual foci of ATC with tracheal

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Luca Damiani Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy

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Sabrina Lupo Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Roberta Rossi Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Stefania Bruni Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Mirco Bartolomei Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy

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Stefano Panareo Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy

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Paola Franceschetti Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Paolo Carcoforo Department of Morphology, Section of Surgery, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy

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Giovanni Lanza Department of Medical Sciences, Pathology Unit, University of Ferrara, Ferrara, Italy

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Stefano Pelucchi Department of Biomedical and Surgical Specialization Sciences, University of Ferrara, Ferrara, Italy

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Ettore Degli Uberti Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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Maria Chiara Zatelli Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy

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between BRAF V600E somatic mutation and PTC persistence. Materials and Methods Patients We selected 80 patients submitted to thyroidectomy for PTC with BRAF V600E somatic mutation, operated on between 2007 and 2014, for a prospective follow

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