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Maria Mavromati Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Verdiana Caironi Department of Internal Medicine, Lugano Regional Hospital, Ente Ospedaliero Cantonale, Via Tesserete Lugano, Switzerland

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Essia Saiji Department of Pathology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Maria-Isabel Vargas Department of Neuroradiology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Shahan Momjian Department of Neurosurgery, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Stephanie Andrade-Lopes Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Capucine Gubert Department of Internal Medicine, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Marco Stefano Demarchi Department of Thoracic and Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Ismini Mainta Department of Nuclear Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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François R Jornayvaz Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Kaveh Samii Department of Hematology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Grégoire Stalder Service and Central Laboratory of Hematology, Lausanne University Hospital, rue du Bugnon Lausanne, Switzerland.
Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland

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Sophie Leboulleux Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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suprasellar tumor (SUV 8.7) and slightly increased FDG avidity (SUV 4.1) of the thyroid gland described as related to the known thyroiditis ( Fig. 2B ) and of inguinal lymph nodes (SUV 3.1). Thyroid ultrasound showed increased thyroid volume (19 mL), with

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Dulani Kottahachchi Department of Endocrinology and Diabetes, The Alfred Hospital, Australia

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Duncan J. Topliss Department of Endocrinology and Diabetes, The Alfred Hospital, Australia
Department of Medicine, Monash University, Melbourne, VIC, Australia

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and it usually shows diffuse low echogenicity of the thyroid gland in IgG4-related HT, whereas non-IgG4 thyroiditis is associated with diffuse, coarse echogenicity [ 22 ]. This may be due to the higher degree of stromal fibrosis and follicular cell

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Brigitte Decallonne Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Annick Van den Bruel Department of Endocrinology, General Hospital St Jan, Bruges, Belgium

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Gilles Macq Department of Research, Belgian Cancer Registry, Brussels, Belgium

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Nathalie Elaut Department of Research, Belgian Cancer Registry, Brussels, Belgium

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Harlinde De Schutter Department of Research, Belgian Cancer Registry, Brussels, Belgium

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% CI for each proportion was calculated using a normal approximation on the logit scale. To allow comparison between the regions, z -scores and corresponding p values were computed. For the interregional comparison of the surgical thyroid gland

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Bruno Bouça Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Ana Cláudia Martins Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Paula Bogalho Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Lídia Sousa Cardiology Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Tiago Bilhim Interventional Radiology Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Filipe Veloso Gomes Interventional Radiology Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Élia Coimbra Interventional Radiology Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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Ana Agapito Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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José Silva-Nunes Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal

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occurring in a normal thyroid gland. A mixed type is also recognized. AIT can be a dangerous condition because it may exacerbate underlying cardiac abnormalities leading to increased morbidity and mortality, especially in patients with left ventricular

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Jesper Roed Sorensen Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark
OPEN, Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark

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Jeppe Faurholdt Lauridsen Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark

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Helle Døssing Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark

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Nina Nguyen Department of Radiology, Odense University Hospital, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Christian Godballe Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark

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an enlarged thyroid gland (thyroid volume >18 mL in women and >25 mL in men [ 23 ]) with 1 or more nodules. Serum levels of total thyroxine (T 4 ) and total triiodothyronine (T 3 ) had to be within the normal range (67–134 nmol/L and 1.35–2.33 nmol

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Stine Linding Andersen Departments of Endocrinology, Aalborg, Denmark
Departments of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Peter Laurberg Departments of Endocrinology, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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the activity of the NIS (sodium-iodide supporter) in the thyroid gland via thyroid autoregulation, with a compensatory increase in thyroid iodide clearance to keep thyroid absolute iodide uptake (AIU) unaltered for thyroid hormone production [ 3

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Sofia Macedo Institute for Research & Innovation in Health, University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal

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Ana Pestana Institute for Research & Innovation in Health, University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal

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Liliana Santos Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal
North Lisbon University Hospital Center, Lisbon, Portugal

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Celestino Neves Faculty of Medicine, University of Porto, Porto, Portugal
University Hospital Center of São João, Porto, Portugal

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Susana Guimarães Faculty of Medicine, University of Porto, Porto, Portugal
University Hospital Center of São João, Porto, Portugal

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Amaro Duarte-Neto Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil

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Marisa Dolhnikoff Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil

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Paulo Saldiva Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil

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Georgina Alves Institute for Research & Innovation in Health, University of Porto, Porto, Portugal

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Rute Oliveira Institute for Research & Innovation in Health, University of Porto, Porto, Portugal

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Didier Cabanes Institute for Research & Innovation in Health, University of Porto, Porto, Portugal

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Fátima Carneiro Institute for Research & Innovation in Health, University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal
University Hospital Center of São João, Porto, Portugal

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Manuel Sobrinho-Simões Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal
University Hospital Center of São João, Porto, Portugal

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Paula Soares Institute for Research & Innovation in Health, University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Faculty of Medicine, University of Porto, Porto, Portugal

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also affect endocrine organs, such as the thyroid gland ( 1 , 2 ). Angiotensin-converting enzyme 2 (ACE-2) receptor was reported as the functional receptor of the SARS-CoV virus ( 3 ). Recent studies reported that SARS-CoV-2 also employs the same

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Mahdi Kamoun Endocrinology and Metabolism Department

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Michèle d'Herbomez Department of Nuclear Medicine, Lille University Hospital, Lille

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Christine Lemaire Department of Endocrinology, Regional Hospital of Béthune, Béthune

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Armelle Fayard Endocrinology and Metabolism Department

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Rachel Desailloud Endocrinology and Metabolism Department, Amiens University Hospital, Amiens, France

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Damien Huglo Department of Nuclear Medicine, Lille University Hospital, Lille

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Jean-Louis Wemeau Endocrinology and Metabolism Department

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expression in thyrocytes. Fas antigen is functionally expressed on the surface of thyrocytes, and TSH inhibits Fas antigen-mediated apoptosis of thyrocytes resulting in the promotion of growth of the thyroid gland [ 15 ]. Intercellular adhesion molecule-1 and

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Mohamed E. Ahmed Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Mohamed A. Mahgoub Khartoum Teaching Hospital, Khartoum, Sudan

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Mohamed G. Alnedar Khartoum Teaching Hospital, Khartoum, Sudan

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Seif I. Mahadi Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Maha Alzubeir Surgery, Faculty of Medicine, Khartoum, Sudan

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Lamyaa A.M. El Hassan University of Ahfad, Khartoum, Sudan

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ElWaleed M. Elamin Alzaeim Alazhari University, Khartoum, Sudan

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Ahmed Mohammed El Hassan University of Khartoum, Khartoum, Sudan

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mediastinum. During the surgical procedure, intraoperative assessment of the mass indicated the need for a median sternotomy that was carried out and the mass macroscopically appeared different and totally separate from the thyroid gland. A review of the

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Marina Morais Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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João Capela-Costa Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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Luís Matos-Lima Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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José Costa-Maia Endocrine and Cervical Unit, General Surgery Department, São João Medical Center, Porto, Portugal

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procedure, the thyroid gland and blood vessels were exposed. As it was not possible to identify the RLN on the right side using the usual anatomical landmarks, the possibility of an NRLN was raised. In the first patient, we identified a branch of the right

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