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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
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Endocrine Section, Beacon Hospital, Dublin, Ireland.
School of Medicine, University College Dublin, Ireland
Endocrinology Department, St Vincent’s University Hospital, Dublin, Ireland
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). Rarely, cases of RTHβ with thyroid cancer (generally papillary microcarcinoma; one metastatic) have been reported ( 36 , 37 , 38 , 39 ) with favorable clinical outcomes despite incomplete TSH suppression following thyroid ablation ( 38
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Department of Pediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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Endocrine Unit, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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, sporadic toxic adenoma, hyperfunctioning papillary or follicular carcinoma Mild symptoms of hyperthyroidism; asymmetric thyroid gland or thyroid nodule at palpation or US Elevated (F)T4 and (F)T3 levels; suppressed TSH level; negative TSHRAb
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Department of Pathology, Haukeland University Hospital Bergen, Bergen, Norway
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Department of Medical Genetics, St. Olavs University Hospital, Trondheim, Norway
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Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway
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and lymph node capsule in node-positive papillary and medullary thyroid cancer: different biology . Eur J Surg Oncol . 2015 Jun ; 41 ( 6 ): 766 – 72 . 10.1016/j.ejso.2014.10.049 25468749 0748-7983 15 Roman S , Lin R , Sosa JA
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comorbidities at the time of DTC diagnosis, being cardiovascular disease in 28.6% (61/213) of them. Concerning primary tumour characteristics, median (Q1–Q3) size was 40 (25.0–57.0) mm. Almost 60% (125/209) of patients presented with papillary thyroid carcinoma
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University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, Basel, Switzerland
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Division of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland
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in papillary thyroid microcarcinoma . Onco Targets Ther . 2016 ; 9 : 5307 – 16 . http://dx.doi.org/10.2147/OTT.S107913 . 35 Kwak HY , Dionigi G , Liu X , Sun H , Woo SU , Son GS , . Predictive factors for longer operative
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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a series of specific nuclear features. According to the last WHO classification [ 1 ], it can be sub-classified according to the pathological features as papillary microcarcinoma, as encapsulated, follicular, diffuse sclerotizing, tall cell, columnar
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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100,000 women and 0.3 per 100,000 men) ( 1 ). In the last decades, its worldwide incidence has been continuously rising, largely driven by microcarcinomas of the papillary histotype ( 2 , 3 ), and mostly due to an improvement in diagnostic procedures
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, 28 ]. Serum Ct is a very sensitive and specific marker of MTC [ 29 ] although some rare pathological conditions can be accompanied by increased levels of serum Ct [ 28 ]. Moreover, both autoimmune thyroiditis and small papillary thyroid cancer can be