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infiltration on histopathology evaluation ( 2 , 3 , 4 ). Debate regarding the prognosis of DSV-PTC is not closed. Several studies were published in the last years, comparing outcomes and prognosis of this variant to the outcomes of classic and high-risk
Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain
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classified as differentiated TC (DTC), including PTC and follicular thyroid carcinoma (FTC), and non-DTC, which included all other types of malignancies (medullary carcinoma, undifferentiated carcinoma, metastatic thyroid, and lymphoma). Finally, we compared
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University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, Basel, Switzerland
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Division of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland
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. Incidence of 30-Day Readmissions The overall incidence of all-cause 30-day hospital readmission was 2.2%. Male patients had a higher risk of readmission within 30 days to the index hospital than female patients (3.3 vs. 1.9%; adjusted risk ratio [RR] 1
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neuromuscular transmission as the common feature [ 6 ] and very rarely is associated with lymphoblastic malignancies. Thymic epithelial tumors can be challenging to manage because of local invasion of mediastinal structures and a high recurrence rate [ 7 ]. Non
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]. Approximately 20-30% of the patients with differentiated thyroid cancer have loco-regional recurrences [ 2 ]. To better predict the recurrence rate, ATA risk stratification of patients in low-, intermediate- and high-risk categories can be used. Persistent or
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increased risk of recurrence compared with those who underwent immediate surgery [ 14 ]. Lobectomy for the treatment of PTMC did not pose any significantly higher risk of recurrence (3.8%) than total thyroidectomy (1.6%) during 8.5 years of follow-up, after
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Epithelial cancers of the thyroid gland constitute the majority of thyroid malignancies (about 95%) and include papillary, follicular, hurtle cell, anaplastic, and medullary thyroid cancers. The nonepithelial cancers constitute less than 5% of all thyroid
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Neurofibromatosis Expert Team, Maastricht University Medical Centre, Maastricht, The Netherlands
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Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands
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, significantly higher risks have been reported for other malignancies [ 10 ]. Despite the increased risk of endocrine tumors in NF1, the current literature on thyroid cancer in this population mainly consists of case reports as summarized in Table 1 [ 11 - 20
Department of Medicine, Endocrinology Service, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil
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Department of Medicine, Endocrinology Service, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil
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bone metastases of all patients included. Likewise, 39 patients (78%) developed at least 1 SRE during the period assessed. As expected, the most common SRE was the need of EBRT in order to control pain or diminish the risk of fracture (50%). In
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IdiSNA (Instituto de investigación en la salud de Navarra), Pamplona, Spain
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sensitivity [ 12 , 13 ]. The new approaches in diagnostics based on genetic abnormalities are testing a number of genetic alterations simultaneously. Several platforms are currently marketed to improve the malignancy risk assessment in indeterminate nodules