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  • Thyroid-stimulating hormone x
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Shakeel Kautbally Divisions of Endocrinology and Nutrition, Université Catholique de Louvain, Brussels, Belgium

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Orsalia Alexopoulou Divisions of Endocrinology and Nutrition, Université Catholique de Louvain, Brussels, Belgium

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Chantal Daumerie Divisions of Endocrinology and Nutrition, Université Catholique de Louvain, Brussels, Belgium

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François Jamar Divisions of Nuclear Medicine, Université Catholique de Louvain, Brussels, Belgium

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Michel Mourad Divisions of Endocrine Surgery, St. Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium

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Dominique Maiter Divisions of Endocrinology and Nutrition, Université Catholique de Louvain, Brussels, Belgium

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Introduction Graves’ disease (GD) is a common autoimmune disorder mainly characterized by an abnormal production of antibodies binding to and activating TSH receptor, referred to as thyroid-stimulating immunoglobulins (TSI), thereby leading to

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000339473
Volume/Issue:
Volume 1: Issue 2
Free access
Nadine Johnson Departments of Obstetrics and Gynaecology, University of the West Indies, Kingston, Jamaica

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Vikash Chatrani Departments of Obstetrics and Gynaecology, University of the West Indies, Kingston, Jamaica

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Anna-Kay Taylor-Christmas Departments of Obstetrics and Gynaecology, University of the West Indies, Kingston, Jamaica

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Eric Choo-Kang Departments of Chemical Pathology, University of the West Indies, Kingston, Jamaica

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Monica Smikle Departments of Microbiology, University of the West Indies, Kingston, Jamaica

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Rosemarie Wright-Pascoe Departments of Medicine, University of the West Indies, Kingston, Jamaica

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Karen Phillips Departments of Medicine, University of the West Indies, Kingston, Jamaica

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Marvin Reid Tropical Metabolism Research Institute, University of the West Indies, Kingston, Jamaica

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Introduction Hypothyroidism is the most common disorder of thyroid function in pregnancy [ 1 ]. Subclinical hypothyroidism (SCH) is defined as serum thyroid-stimulating hormone (TSH) >97.5% and normal free thyroxine (FT 4 ), with or without

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367654
Volume/Issue:
Volume 3: Issue 4
Free access
Carla Colombo Endocrine Oncology Unit, Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Daniele Ceruti Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Massimiliano Succi Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Simone De Leo Endocrine Oncology Unit, Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Matteo Trevisan Endocrine Oncology Unit, Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Claudia Moneta Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Laura Fugazzola Endocrine Oncology Unit, Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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and 2/6 (33%) on vandetanib. No patients in SELP treatment had a reduced response after ACTH stimulation. ACTH, adrenocorticotropic hormone; p #, patient ID; L, lenvatinib; V, vandetanib; S, selpercatinib. Table 2 Results of adrenal

Article Type:
Research Article
Collections:
Thyroid cancer - basic and translational
DOI:
https://doi.org/10.1530/ETJ-23-0246
Volume/Issue:
Volume 13: Issue 3
Open access
María de los Ángeles Garayalde Gamboa Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Melina Saban Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Marina Ines Curriá Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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disease and thyroid surgery. Currently, the first-line treatment is oral levothyroxine (LT4). However, there are cases in whom the dose of oral LT4 is not sufficient to reverse the symptoms or thyroid-stimulating hormone (TSH) levels (TSH >4.5 mIU/L after

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000503324
Volume/Issue:
Volume 8: Issue 6
Free access
Sita Virakul Departments of Immunology, University Medical Center Rotterdam
Internal Medicine, Erasmus MC, University Medical Center Rotterdam

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Leendert van Steensel Departments of Immunology, University Medical Center Rotterdam

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Virgil A.S.H. Dalm Departments of Immunology, University Medical Center Rotterdam

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Dion Paridaens Rotterdam Eye Hospital, Rotterdam, The Netherlands
Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland

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P. Martin van Hagen Departments of Immunology, University Medical Center Rotterdam
Internal Medicine, Erasmus MC, University Medical Center Rotterdam
Rotterdam Eye Hospital, Rotterdam, The Netherlands

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Willem A. Dik Departments of Immunology, University Medical Center Rotterdam

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processes contribute to orbital tissue expansion in GO. Autoantibodies directed against the thyroid stimulating hormone receptor (TSHR) are considered as important contributors to GO and TSHR autoantibody titers correlate positively with disease

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000367968
Volume/Issue:
Volume 3: Issue 4
Free access
Claire L Wood Department of Paediatric Endocrinology, Great North Children’s Hospital, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK

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Niamh Morrison Department of Paediatric Endocrinology, Great North Children’s Hospital, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK

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Michael Cole Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Newcastle upon Tyne, UK

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Malcolm Donaldson Department of Child Health, University of Glasgow School of Medicine, Glasgow, UK

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David B Dunger Department of Paediatrics, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK
Wellcome Trust-MRC Institute of Metabolic Sciences, University of Cambridge, Cambridge, UK

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Ruth Wood Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK

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Simon H S Pearce Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
Department of Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK

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Timothy D Cheetham Department of Paediatric Endocrinology, Great North Children’s Hospital, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK

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on behalf of the British Society for Paediatric Endocrinology and Diabetes (BSPED)

-diagnosis. We describe the detailed baseline characteristics of the cohort including the frequency of eye signs linked to thyrotoxicosis as well as initial change in BMI on ATD. We also examined the early serum thyroid-stimulating hormone (TSH) and free

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-21-0043
Volume/Issue:
Volume 11: Issue 1
Open access
Sandrine Donadio-Andréi Siamed'Xpress, Hôtel Technologique Morandat, Gardanne

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Karim Chikh Hospices Civils de Lyon, Lyon
CARMEN-INSERM U1060, Université Claude Bernard Lyon 1, Faculté de Médecine et de Maïeutique Lyon Sud - Charles Mérieux, Oullins
Société Française de Médecine Nucléaire, Groupe de Biologie Spécialisée, Centre Antoine Béclère, Paris

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Christine Heuclin BioSIMS Technologies, Seine Biopolis II, Rouen

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Elisabetta Kuczewski Hospices Civils de Lyon, Lyon

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Anne Charrié Hospices Civils de Lyon, Lyon
CARMEN-INSERM U1060, Université Claude Bernard Lyon 1, Faculté de Médecine et de Maïeutique Lyon Sud - Charles Mérieux, Oullins
Société Française de Médecine Nucléaire, Groupe de Biologie Spécialisée, Centre Antoine Béclère, Paris

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Anne-Sophie Gauchez Société Française de Médecine Nucléaire, Groupe de Biologie Spécialisée, Centre Antoine Béclère, Paris
Laboratoire du Service de Médecine Nucléaire, Centre Hospitalier de Chambéry, Chambéry
Pôle de Biologie, Centre Hospitalier et Universitaire de Grenoble
UMR-S INSERM 1037, Grenoble, France

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Catherine Ronin Siamed'Xpress, Hôtel Technologique Morandat, Gardanne

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Introduction Over the past years substantial variability among thyroid-stimulating hormone (TSH) measurements has been extensively described, largely influencing the critical discrimination between normal and diseased TSH levels [ 1 ]. To

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000449463
Volume/Issue:
Volume 6: Issue 1
Free access
Valentina Cirello Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Marina Lugaresi Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Claudia Moneta Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Patrice Dufour Department of Clinical, Forensic and Environmental Toxicology, University hospital of Liege (CHU Liège), CHU (B35), Liege, Belgium
Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium

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Alessandro Manzo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Erika Carbone Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Carla Colombo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Laura Fugazzola Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Corinne Charlier Department of Clinical, Forensic and Environmental Toxicology, University hospital of Liege (CHU Liège), CHU (B35), Liege, Belgium
Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium

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Catherine Pirard Department of Clinical, Forensic and Environmental Toxicology, University hospital of Liege (CHU Liège), CHU (B35), Liege, Belgium
Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium

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increased thyroid-stimulating hormone (TSH) levels ( 6 ), which have been found to represent a risk factor for thyroid cancer onset ( 7 ). Of EDCs, per- and poly-fluoroalkyl substances (PFAS), poly-chlorinated biphenyls (PCBs), and

Article Type:
Research Article
Collections:
Environment and thyroid function
DOI:
https://doi.org/10.1530/ETJ-23-0192
Volume/Issue:
Volume 13: Issue 3
Open access
Érique José F. Peixoto de Miranda Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil

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Márcio Sommer Bittencourt Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil

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Itamar S. Santos Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil

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Paulo A. Lotufo Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil

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Isabela M. Benseñor Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil

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Introduction The link between subclinical hypothyroidism (SCH), which is defined as high serum thyroid-stimulating hormone (TSH) concomitant with normal serum free thyroxine levels (fT 4 ) [ 1 ], and cardiovascular disease remains

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000448683
Volume/Issue:
Volume 5: Issue 4
Free access
N. Papanikolaou Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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P. Perros Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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diffuse goiter was observed. Her proximal muscles were significantly tender. Muscle power and tendon reflexes were within the normal range. Laboratory evaluation showed a suppressed serum thyroid stimulating hormone (TSH; <0.05 mU/l, normal range 0

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000343826
Volume/Issue:
Volume 1: Issue 4
Free access