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Ola Lindgren Department of Endocrinology, Lund University, Malmö, Sweden
Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden

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Pernilla Asp Department of Oncology, Skåne University Hospital, Lund, Sweden

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Anna Sundlöv Department of Oncology, Lund University, and Department of Clinical Sciences, Skåne University Hospital, Lund, Sweden

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Jan Tennvall Department of Oncology, Lund University, and Department of Clinical Sciences, Skåne University Hospital, Lund, Sweden

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Bushra Shahida Department of Clinical Sciences Malmö, and Diabetes and Endocrinology, Lund University, Malmö, Sweden

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Tereza Planck Department of Endocrinology, Lund University, Malmö, Sweden
Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden

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Peter Åsman Department of Clinical Sciences Malmö, Ophthalmology, Lund University, and Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden

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Mikael Lantz Department of Endocrinology, Lund University, Malmö, Sweden
Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden

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Introduction In Graves’ disease (GD), immunocompetent cells infiltrate thyroid tissue with release of TSH-receptor antibodies (TRAb), resulting in hyperthyroidism. The triggering of the autoimmune response depends on the interplay of genetic

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000495504
Volume/Issue:
Volume 8: Issue 2
Free access
Bing Han Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Chi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Ningjian Wang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Jie Yu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Jing Cheng Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yingchao Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Chunfang Zhu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yingli Lu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Background Autoimmune thyroid disease (AITD), including autoimmune hypothyroidism (Hashimoto thyroiditis) and autoimmune hyperthyroidism (Graves’ disease), affects 2–5% of the general population. Its risk factors included genetic

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000506701
Volume/Issue:
Volume 10: Issue 1
Free access
Caiyan Mo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Han Chen Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Qi Zhang Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Ying Guo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Liyong Zhong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Introduction Graves' disease (GD) is an autoimmune disease of the thyroid gland and is the most common cause of hyperthyroidism. The annual incidence is 20–50 cases per 100,000 people, with a peak incidence between the ages of 30 and 50. The

Article Type:
Review Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0223
Volume/Issue:
Volume 12: Issue 4
Open access
Eijun Nishihara Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Nobuyuki Amino Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Takumi Kudo Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Kazuyoshi Kohsaka Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Shuji Fukata Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsushige Nishikawa Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Hirotoshi Nakamura Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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, Refetoff S . Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases . Clin Endocrinol (Oxf) . 1976 Mar ; 5 ( 2 ): 115 – 25 . 10.1111/j

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000501033
Volume/Issue:
Volume 8: Issue 5
Open access
Liyuan Liu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Yang Yu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Lei Chen Department of Ultrasound, Peking University First Hospital, Beijing, People’s Republic of China

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Yang Zhang Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Guizhi Lu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Ying Gao Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Junqing Zhang Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Introduction Hashimoto’s thyroiditis (HT) is a common autoimmune thyroid disease characterized by goitre, lymphoplasmacytic infiltration of parenchyma, and positivity for serum antibodies specific to thyroid antigens (including thyroid

Article Type:
Research Article
Collections:
Thyroid autoimmunity
DOI:
https://doi.org/10.1530/ETJ-21-0144
Volume/Issue:
Volume 11: Issue 3
Open access
Alex Stagnaro-Green University of Illinois College of Medicine at Rockford, Rockford, Ill., USA

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responds adequately to the increased demands experienced during pregnancy. However, in women with decreased reserve, either due to autoimmune thyroid disease or iodine deficiency, subclinical hypothyroidism (SCH) develops during pregnancy despite the fact

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000363293
Volume/Issue:
Volume 3: Issue 2
Free access
Jan Jiskra 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jiří Horáček 4th Department of Medicine, Faculty of Medicine, Charles University, University Hospital Hradec Králové, Czech Republic

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Sylvie Špitálníková Department of Nuclear Medicine, District Hospital, Havlíčkův Brod, Czech Republic

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Jan Paleček 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Zdeňka Límanová 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Jan Krátký 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Drahomíra Springer Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Kristýna Žabková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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Hana Vítková 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic

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, history of pregnancy loss, preterm delivery, or infertility, multiple prior pregnancies, family history of autoimmune thyroid disease or thyroid dysfunction, morbid obesity (BMI ≥40 kg/m 2 ), use of amiodarone or lithium, or recent administration of

Article Type:
Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-21-0011
Volume/Issue:
Volume 11: Issue 2
Open access
Diogo Mendes Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal

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Carlos Alves Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal

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Nuno Silverio Merck S.A., Algés, Portugal

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Francisco Batel Marques Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal

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autoimmune thyroid disease by race/ethnicity in US military personnel . JAMA . 2014 Apr ; 311 ( 15 ): 1563 – 5 . 10.1001/jama.2013.285606 24737370 0098-7484 9 Mammen JS , McGready J , Ladenson PW , Simonsick EM . Unstable Thyroid

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000499751
Volume/Issue:
Volume 8: Issue 3
Free access
Silvia Turcios National Institute of Endocrinology, Cuba

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Juan J. Lence-Anta Institute of Oncology and Radiobiology, Cuba

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Jose-Luis Santana Institute of Oncology and Radiobiology, Cuba

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Celia M. Pereda Institute of Oncology and Radiobiology, Cuba

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Milagros Velasco Institute of Oncology and Radiobiology, Cuba

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Mae Chappe Institute of Oncology and Radiobiology, Cuba

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Idalmis Infante Cuban Health Public Ministry, Havana, Cuba

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Marlene Bustillo Institute of Oncology and Radiobiology, Cuba

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Anabel García Institute of Oncology and Radiobiology, Cuba

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Enora Clero Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Stephane Maillard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Regla Rodriguez Cuban Health Public Ministry, Havana, Cuba

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Constance Xhaard Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Yan Ren Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Carole Rubino Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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Rosa M. Ortiz Institute of Oncology and Radiobiology, Cuba

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Florent de Vathaire Radiation Epidemiology Group, Unit 1018-Inserm, France
The Gustave Roussy Cancer Center, France
Paris-Sud University, Villejuif, France

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family history of thyroid disease or with signs of thyroid disease. Furthermore, we excluded women during menstruation, pregnant women and women who had delivered within the last 12 months because these conditions may affect thyroid size. The study was

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000371346
Volume/Issue:
Volume 4: Issue 1
Free access
John H. Lazarus Centre for Endocrine and Diabetes Sciences, Cardiff University, Cardiff, UK

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features of Graves’ disease in the first trimester of pregnancy may occur due to stimulation of the thyroid both by human chorionic gonadotropin and thyrotropin receptor-stimulating antibodies [ 3 , 4 , 5 ]. The markedly increased thyroid hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000336102
Volume/Issue:
Volume 1: Issue 1
Free access