Natsuko Watanabe
Natsuko Watanabe
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Jaeduk Yoshimura Noh
Jaeduk Yoshimura Noh
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Naomi Hattori
Naomi Hattori
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Kenji Iwaku
Kenji Iwaku
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Nami Suzuki
Nami Suzuki
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Ai Yoshihara
Ai Yoshihara
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Hidemi Ohye
Hidemi Ohye
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Miho Suzuki
Miho Suzuki
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Masako Matsumoto
Masako Matsumoto
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Kei Endo
Kei Endo
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Yo Kunii
Yo Kunii
Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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Gen Takagi
Gen Takagi
Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan
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Kiminori Sugino
Kiminori Sugino
Department of Surgery, Ito Hospital, Tokyo, Japan
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Koichi Ito
Koichi Ito
Department of Surgery, Ito Hospital, Tokyo, Japan
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cardiovascular prognosis negatively [ 17 - 19 ]. Determining how thyrotoxicosis affects levels of cardiac troponin, which are indicative of minor myocardial damage, is an informative pursuit. However, a small investigation that measured cardiac troponin levels in
Annelies Tonnelier
Annelies Tonnelier
Departments of Endocrinology and General Internal Medicine, Algemeen Ziekenhuis Sint-Elisabeth Zottegem, Zottegem, Belgium
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Jeroen de Filette
Jeroen de Filette
Departments of Endocrinology and General Internal Medicine, Algemeen Ziekenhuis Sint-Elisabeth Zottegem, Zottegem, Belgium
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Ann De Becker
Ann De Becker
Departments of Hematology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel (VUB), Brussels
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Sophie Deweer
Sophie Deweer
Department of Endocrinology and Diabetology, Algemeen Ziekenhuis Sint-Elisabeth Zottegem, Zottegem, Belgium
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Brigitte Velkeniers
Brigitte Velkeniers
Departments of Endocrinology and General Internal Medicine, Algemeen Ziekenhuis Sint-Elisabeth Zottegem, Zottegem, Belgium
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intracellular thyroid hormones into the circulation, which are bound onto new binding sites provided by the plasma or albumin replacement solution, thereby effectively decreasing the total thyroid hormone concentrations. In this report, thyroid hormone levels
John H. Lazarus
John H. Lazarus
Centre for Endocrine and Diabetes Sciences, Cardiff University, Cardiff, UK
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concentration of approximately 150 µg/l [ 10 ]. Although there has been a significant increase in the use of universal salt iodisation in the last 20 years, some countries, including for example the United Kingdom [ 11 ], are still iodine-deficient. Table
Mathieu Spaas
Mathieu Spaas
Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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Brigitte Decallonne
Brigitte Decallonne
Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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Annouschka Laenen
Annouschka Laenen
Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium
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Jaak Billen
Jaak Billen
Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium
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Sandra Nuyts
Sandra Nuyts
Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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of DTC usually consists of total thyroidectomy followed by radioactive iodine (RAI) remnant ablation (RRA). Postoperative administration of RAI serves three major goals: the first is to destroy any residual microscopic disease as well as any remaining
Laura Agate
Laura Agate
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Francesca Bianchi
Francesca Bianchi
Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy
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Federica Brozzi
Federica Brozzi
Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy
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Pierina Santini
Pierina Santini
Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy
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Eleonora Molinaro
Eleonora Molinaro
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Valeria Bottici
Valeria Bottici
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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David Viola
David Viola
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Loredana Lorusso
Loredana Lorusso
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Paolo Vitti
Paolo Vitti
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Rossella Elisei
Rossella Elisei
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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for the management of high-risk patients in whom this procedure has shown a positive impact on recurrence and survival [ 15 , 16 ]. A selective use of RRA is proposed for the IR patients taking into account the level of risk of recurrence as well as
Sara Monteiro-Martins
Sara Monteiro-Martins
Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
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Rosalie B T M Sterenborg
Rosalie B T M Sterenborg
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Oleg Borisov
Oleg Borisov
Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
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Nora Scherer
Nora Scherer
Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany
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Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany
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Yurong Cheng
Yurong Cheng
Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
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Marco Medici
Marco Medici
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Anna Köttgen
Anna Köttgen
Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Alexander Teumer
Alexander Teumer
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
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DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
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required in the iodination process and H 2 O 2 production to form thyroid hormones ( 1 ). Additionally, a previous study showed that on continuous daily administration of calcium channel blockers, a gradual fall in levels of T3 and T4 with a rise in TSH
Georgios K. Markantes
Georgios K. Markantes
Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece
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Marina A. Michalaki
Marina A. Michalaki
Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece
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George A. Vagenakis
George A. Vagenakis
Department of Pediatric Cardiology and Adult Congenital Heart Disease, Onassis Cardiac Surgery Center, Athens, Greece
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Fotini N. Lamari
Fotini N. Lamari
Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece
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Efthymia Pitsi
Efthymia Pitsi
Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece
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Maria Eliopoulou
Maria Eliopoulou
Endocrinology Unit, Karamandanio Hospital, Patras, Greece
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Nicholas G. Beratis
Nicholas G. Beratis
Department of Pediatrics, University of Patras Medical School, Patras, Greece
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Kostas B. Markou
Kostas B. Markou
Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece
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concentrations and suppressed TSH levels, discrimination between AIT1 and AIT2 in order to select the appropriate treatment is often challenging. AIT1 involves excessive thyroid hormone synthesis by autonomously functioning thyroid tissue, which typically occurs
Fabián Pitoia
Fabián Pitoia
Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina
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Erika Abelleira
Erika Abelleira
Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina
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Graciela Cross
Graciela Cross
Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina
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(7th ed.) [ 37 ]. All these patients were classified as being at an intermediate or high risk of recurrence. For inclusion, patients had to present a diagnosis of papillary thyroid cancer (PTC), be older than 18 years and have an undetectable level
Laura Croce
Laura Croce
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Fausta Beneventi
Fausta Beneventi
Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy
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Federica Ripepi
Federica Ripepi
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
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Irene De Maggio
Irene De Maggio
Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy
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Alberto Malovini
Alberto Malovini
Istituti Clinici Scientifici Maugeri IRCCS, Laboratory of Informatics and Systems Engineering for Clinical Research, Pavia (PV), Italy
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Camilla Bellingeri
Camilla Bellingeri
Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy
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Francesca Coperchini
Francesca Coperchini
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
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Marsida Teliti
Marsida Teliti
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Mario Rotondi
Mario Rotondi
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Arsenio Spinillo
Arsenio Spinillo
Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia (PV), Italy
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Flavia Magri
Flavia Magri
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia (PV), Italy
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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Istituti Clinici Scientifici Maugeri IRCCS, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Pavia (PV), Italy
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offspring in these women ( 4 , 5 ), other authors did not describe any association ( 6 ). In this complicated scenario, identifying any possible cause leading to an increase in serum TSH levels during pregnancy that is not due to thyroid autoimmunity
Alessandro Brancatella
Alessandro Brancatella
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Laura Pierotti
Laura Pierotti
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Nicola Viola
Nicola Viola
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Isabella Lupi
Isabella Lupi
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Lucia Montanelli
Lucia Montanelli
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Chiara Cremolini
Chiara Cremolini
Oncology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy
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Paolo Piaggi
Paolo Piaggi
Department of Information Engineering, University of Pisa, Pisa, Italy
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Antonio Chella
Antonio Chella
Pneumology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy
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Andrea Antonuzzo
Andrea Antonuzzo
Oncology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy
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Daniele Sgrò
Daniele Sgrò
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Lucia Antonangeli
Lucia Antonangeli
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Chiara Sardella
Chiara Sardella
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Sandra Brogioni
Sandra Brogioni
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Claudio Marcocci
Claudio Marcocci
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Ferruccio Santini
Ferruccio Santini
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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Francesco Latrofa
Francesco Latrofa
Endocrinology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy
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/mL) Positive 0 0 Level TRAb (<1.5 IU/mL) Positive 0 0 Urinary iodine (100–300 μg/L) 214.2 (180–278) 218.5 (179–287) 0.11 Thyroglobulin (<30 ng/mL) 60.3 (11–480) 51 (6–550) 0
