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that study ( 17 ), previous studies focused exclusively on middle-aged to elderly patients. In addition, common for these previous studies were limited statistical power due to relatively small sample sizes and/or insufficient length of follow-up, and
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Laboratory Specialized Diagnostics & Research, Department of Laboratory Medicine, Amsterdam UMC, University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
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medicine, endocrinology, oncology, biochemistry, radiology ( 24 ) France Management of thyroid dysfunctions in the elderly. French Endocrine Society consensus statement 2019 French Society of Endocrinology ? Internal medicine, endocrinology
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4189 5.7% Auer et al. ( 17 ) 2001 Austria RS 23,638 – Euthyroid 22,300 2.3% oHT 725 Elderly 13.8% RR 5.8 (2.7–8.5) Osman et al. ( 38 ) 2007 UK P
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L . Determinants and clinical implications of thyroid peroxidase antibodies in middle-aged and elderly individuals: the Rotterdam study . Thyroid 2022 32 78 – 89 . ( https://doi.org/10.1089/thy.2021.0403 ) 18 Vandevijvere S Ruttens A Wilmet
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://pubmed.ncbi.nlm.nih.gov/25905406/ ) 8 Kahaly GJ Nieswandt J Mohr-Kahaly S . Cardiac risks of hyperthyroidism in the elderly . Thyroid 1998 8 1165 – 1169 . ( https://doi.org/10.1089/thy.1998.8.1165 ) 9 Nishihara E Ohye H Amino N Takata K Arishima T Kudo T
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://doi.org/10.1111/j.1532-5415.1989.tb07279.x ) 17 Khan SR Peeters RP van Hagen PM Dalm D & Chaker L . Determinants and clinical implications of thyroid peroxidase antibodies in middle-aged and elderly individuals: the Rotterdam Study . Thyroid
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contraindicated in the elderly and in patients at high cardiovascular risk. Among the previously reported cases of TSHoma combined with GD, six cases ( 11 , 12 , 13 , 14 , 15 , 22 ) underwent TRH stimulation tests and three of them ( 13 , 15 , 22 ) also